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Cited by 311

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ELECTRON MICROSCOPIC OBSERVATIONS ON THE ACCUMULATION OF DIVALENT CATIONS IN INTRAMITOCHONDRIAL GRANULES

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Peachey, Lee D.·1964·The Journal of Cell Biology

Abstract

Electron microscopic evidence is presented, from mitochondria in whole cells of toad urinary bladder and from isolated rat kidney mitochondria, indicating that the divalent cations calcium, strontium, and barium are accumulated in granules localized in the mitochondrial matrix. This accumulation occurs under conditions in which divalent ions are present in the medium bathing either whole cells or isolated mitochondria. The evidence indicates that the divalent ions are deposited on, or in a pre-existing granule, possibly in exchange for other ions. It suggests a possible role of the intramitochondrial granules in the regulation of the internal ionic environment of the mitochondrion. Certain biochemical and physiological implications of this phenomenon are discussed.

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Metadata

Authors
Peachey, L. D.
Venue
The Journal of Cell Biology
Published
1964-01-01
Volume
20
Issue
1
Pages
95-111
ISSN
  • 0021-9525 (ISSN-L)
  • 1540-8140
OpenAlex
W2128774469
Cited by
311
References
1
FWCI
17.98
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: ELECTRON MICROSCOPIC OBSERVATIONS ON THE ACCUMULATION OF DIVALENT CATIONS IN INTRAMITOCHONDRIAL GRANULES. https://app.cochat.ai/papers/10.1083/jcb.20.1.95
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Peachey, L. D. (1964). ELECTRON MICROSCOPIC OBSERVATIONS ON THE ACCUMULATION OF DIVALENT CATIONS IN INTRAMITOCHONDRIAL GRANULES. The Journal of Cell Biology. https://doi.org/10.1083/jcb.20.1.95

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