The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
A Notch updated
Open accessAbstract
Cell–cell signaling mediated by the Notch receptor is iteratively involved in numerous developmental contexts, and its dysregulation has been associated with inherited genetic disorders and cancers. The core components of the signaling pathway have been identified for some time, but the study of the modulation of the pathway in different cellular contexts has revealed many layers of regulation. These include complex sugar modifications in the extracellular domain as well as transit of Notch through defined cellular compartments, including specific endosomes.
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Cites
Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
Joutel, A., Corpechot, C., Ducros, A., Vahedi, K., Chabriat, H., Mouton, P., Alamowitch, S., Domenga, V., Cécillion, M., Maréchal, E., et al. (1996) · Nature · doi:10.1038/383707a0 · Cited by 2,068
Wurmser, A. E., Sato, T. K., & Emr, S. D. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.3.551 · Cited by 425
Protein O -fucosyltransferase 1 is an essential component of Notch signaling pathways
Shi, S., & Stanley, P. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0831126100 · Cited by 381
Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling
Acar, M., Jafar-Nejad, H., Takeuchi, H., Rajan, A., Ibrani, D., Rana, N. A., Pan, H., Haltiwanger, R. S., & Bellen, H. J. (2008) · Cell · doi:10.1016/j.cell.2007.12.016 · Cited by 306
Self-citationEndogenous Presenilin-1 Targets to Endocytic Rather Than Biosynthetic Compartments
Lah, J. J., & Levey, A. I. (2000) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2000.0861 · Cited by 84
Two Japanese CADASIL families exhibiting Notch3 mutation R75P not involving cysteine residue
Mizuno, T., Muranishi, M., Torugun, T., Tango, H., Nagakane, Y., Kudeken, T., Kawase, Y., Kawabe, K., Oshima, F., Yaoi, T., et al. (2008) · Internal Medicine · doi:10.2169/internalmedicine.47.1391 · Cited by 49 · cited 1×
“However recent studies have uncovered rare NOTCH3 mutations that do not seem to involve cysteine residues in patients with CADASIL-like symptoms ( Mizuno et al., 2008 ).”
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Cited by
When NRF2 Talks, Who's Listening?
Wakabayashi, N., Slocum, S. L., Skoko, J. J., Shin, S., & Kensler, T. W. (2010) · Antioxidants & Redox Signaling · doi:10.1089/ars.2010.3216 · Cited by 595
Ezratty, E. J., Stokes, N., Chai, S., Shah, A. S., Williams, S. E., & Fuchs, E. (2011) · Cell · doi:10.1016/j.cell.2011.05.030 · Cited by 317
Cohen, M., Georgiou, M., Stevenson, N. L., Miodownik, M., & Baum, B. (2010) · Developmental Cell · doi:10.1016/j.devcel.2010.06.006 · Cited by 272
Whole exome sequencing reveals the major genetic contributors to nonsyndromic tetralogy of Fallot
Page, D. J., Miossec, M. J., Williams, S. G., Monaghan, R. M., Fotiou, E., Cordell, H. J., Sutcliffe, L., Topf, A., Bourgey, M., Bourque, G., et al. (2019) · Circulation Research · doi:10.1161/circresaha.118.313250 · Cited by 189
Endocytic internalization routes required for delta/notch signaling
Windler, S. L., & Bilder, D. (2010) · Current Biology · doi:10.1016/j.cub.2010.01.049 · Cited by 113
Metadata
- Authors
- Tien, A.-C., Rajan, A., & Bellen, H. J.
- Venue
- Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 2009-03-02
- Volume
- 184
- Issue
- 5
- Pages
- 621-629
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2017423460
- Cited by
- 170
- References
- 6
- FWCI
- 10.56
- Type
- journal article
- Language
- en
- Open access
- green
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- Tien, A.-C., Rajan, A., & Bellen, H. J. (2009). A Notch updated. Journal of Cell Biology. https://doi.org/10.1083/jcb.200811141
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
