The DOI matches its Crossref record; 92 of the 92 references it cites were found in a registry or an index.
The intracellular dynamic of protein palmitoylation
Open accessAbstract
S-palmitoylation describes the reversible attachment of fatty acids (predominantly palmitate) onto cysteine residues via a labile thioester bond. This posttranslational modification impacts protein functionality by regulating membrane interactions, intracellular sorting, stability, and membrane micropatterning. Several recent findings have provided a tantalizing insight into the regulation and spatiotemporal dynamics of protein palmitoylation. In mammalian cells, the Golgi has emerged as a possible super-reaction center for the palmitoylation of peripheral membrane proteins, whereas palmitoylation reactions on post-Golgi compartments contribute to the regulation of specific substrates. In addition to palmitoylating and depalmitoylating enzymes, intracellular palmitoylation dynamics may also be controlled through interplay with distinct posttranslational modifications, such as phosphorylation and nitrosylation.
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Cited by
Local palmitoylation cycles define activity-regulated postsynaptic subdomains
Fukata, Y., Dimitrov, A., Boncompain, G., Vielemeyer, O., Perez, F., & Fukata, M. (2013) · Journal of Cell Biology · doi:10.1083/jcb.201302071 · Cited by 262
Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy
Schapansky, J., Nardozzi, J. D., Felizia, F., & LaVoie, M. J. (2014) · Human Molecular Genetics · doi:10.1093/hmg/ddu138 · Cited by 226
Toll-like receptor mediated inflammation requires FASN-dependent MYD88 palmitoylation
Kim, Y.-C., Lee, S. E., Kim, S. K., Jang, H.-D., Hwang, I., Jin, S., Hong, E.-B., Jang, K.-S., & Kim, H.-S. (2019) · Nature Chemical Biology · doi:10.1038/s41589-019-0344-0 · Cited by 184
CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes
Dimas, P., Montani, L., Pereira, J. A., Moreno, D., Trötzmüller, M., Gerber, J., Semenkovich, C. F., Köfeler, H. C., & Suter, U. (2019) · eLife · doi:10.7554/elife.44702 · Cited by 178
Metadata
- Authors
- Salaun, C., Greaves, J., & Chamberlain, L. H.
- Venue
- Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 2010-12-27
- Volume
- 191
- Issue
- 7
- Pages
- 1229-1238
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2120774566
- Cited by
- 355
- References
- 92
- FWCI
- 7.80
- Type
- journal article
- Language
- en
- Open access
- hybrid
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