The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

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Items 101–200 of 232

1. Bone and morphogenetic protein signalling and muscle mass
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2. FAPs orchestrate homeostasis of muscle physiology and pathophysiology
   Kai Yin, Chengmin Zhang, Zihan Deng, Xiaoyu Wei, Tingwen Xiang, Chuan He Yang, Can Chen, Yueqi Chen, Fei Luo · 2024 · The FASEB Journal
3. Mechanisms and Countermeasures for Muscle Atrophy in Microgravity
   Yizhou Liu, Xiaojian Cao, Qiuzhi Zhou, Chunchu Deng, Yujie Yang, Danxia Huang, Hongmei Luo, Song Zhang, Yajie Li, Jia Xu et al. · 2024 · Cells
4. Drosophila Activin signaling promotes muscle growth through InR/dTORC1 dependent and independent processes
   Myung-Jun Kim, Michael B. O’Connor · 2020 · Development
5. Clinical Relevance and Mechanisms of Antagonism Between the BMP and Activin/TGF-β Signaling Pathways
   Aaron M. Hudnall, Jon W. Arthur, Jonathan Wayne Lowery · 2016 · Journal of Osteopathic Medicine
6. Transcriptional Pathways Associated with Skeletal Muscle Changes after Spinal Cord Injury and Treadmill Locomotor Training
   Céline Baligand, Yiwen Chen, Fan Ye, Sachchida Nand Pandey, San-Huei Lai Polo, Min Liu, Krista Vandenborne · 2015 · BioMed Research International
7. Transcriptional programming of translation by BCL6 controls skeletal muscle proteostasis
   Krithika Ramachandran, Christopher R. Futtner, Meredith A. Sommars, Mattia Quattrocelli, Yasuhiro Omura, Ellen Fruzyna, Janice C. Wang, Nathan J. Waldeck, Madhavi D. Senagolage, Carmen G. Telles et al. · 2024 · Nature Metabolism
8. Bone Morphogenetic Protein 7 Gene Delivery Improves Cardiac Structure and Function in a Murine Model of Diabetic Cardiomyopathy
   Mitchel Tate, Nimna Perera, Darnel Prakoso, Andrew M. Willis, Minh Deo, Osezua Oseghale, Hongwei Qian, Daniel G. Donner, Helen Kiriazis, Miles J. De Blasio et al. · 2021 · Frontiers in Pharmacology
9. Long Non-Coding RNA Myoparr Regulates GDF5 Expression in Denervated Mouse Skeletal Muscle
   Hitachi, Keisuke, Nakatani, Masashi, Tsuchida, Kunihiro · 2019 · Non-Coding RNA
10. Local versus systemic control of bone and skeletal muscle mass by components of the transforming growth factor-β signaling pathway
    Yewei Liu, Adam Lehar, Renata Rydzik, Harshpreet Chandok, Yun‐Sil Lee, Daniel W. Youngstrom, Joshy George, Martin Matthew Matzuk, Emily L. Germain‐Lee, Se‐Jin Lee · 2021 · Proceedings of the National Academy of Sciences
11. The 2022 On-site Padua Days on Muscle and Mobility Medicine hosts the University of Florida Institute of Myology and the Wellstone Center, March 30 - April 3, 2022 at the University of Padua and Thermae of Euganean Hills, Padua, Italy: The collection of abstracts
    Hugh Lee Sweeney, Stefano Masiero, Ugo Carraro · 2022 · European Journal of Translational Myology
12. Cancer Cachexia: Signaling and Transcriptional Regulation of Muscle Catabolic Genes
    Vinay Kumar Rao, Dipanwita Das, Reshma Taneja · 2022 · Cancers
13. Gonad-related factors promote muscle performance gain during postnatal development in male and female mice
    Vanessa Ueberschlag-Pitiot, Amalia Stantzou, Julien Messéant, Mégane Lemaître, Daniel J. Owens, Philippe Noirez, Pauline Roy, Onnik Agbulut, Daniel METZGER, Arnaud Ferry · 2017 · American Journal of Physiology-Endocrinology and Metabolism
14. Interval running training improves age‐related skeletal muscle wasting and bone loss: Experiments with ovariectomized rats
    Jeong‐Seok Kim, Jin Jeon, Jin‐Jeong An, Ho‐Keun Yi · 2019 · Experimental Physiology
15. The MuSK-BMP pathway maintains myofiber size in slow muscle through regulation of Akt-mTOR signaling
    Diego Jaime, Lauren A. Fish, Laura A. Madigan, Chengjie Xi, Giorgia Piccoli, Madison D. Ewing, Bert Blaauw, Justin R. Fallon · 2024 · Skeletal Muscle
16. Signaling networks governing skeletal muscle growth, atrophy, and cachexia
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17. Decreased expression of H19/miR-675 ameliorates muscle atrophy by regulating the IGF1R/Akt/FoxO signaling pathway
    He Zhang, Fei Wang, Xiangsheng Pang, Yue Zhou, Shiming Li, Wenjiong Li, Peng Zhang, Xiaoping Chen · 2023 · Molecular Medicine
18. Skeletal muscle Ca2+ mishandling: Another effect of bone-to-muscle signaling
    Jenna N. Regan, David L. Waning, Theresa A. Guise · 2015 · Seminars in Cell and Developmental Biology
19. Bone morphogenetic protein signaling in rotator cuff muscle atrophy and fatty infiltration
    Xinke Liu, Shivali Joshi, Bharat Ravishankar, Dominique Laron, H.T. Kim, Brian Thomas Feeley · 2019 · Muscles Ligaments and Tendons Journal
20. The MyoGravity project to study real microgravity effects on human muscle precursor cells and tissue
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21. Identification of satellite cells from anole lizard skeletal muscle and demonstration of expanded musculoskeletal potential
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22. Pharmacology of doping agents—mechanisms promoting muscle hypertrophy
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23. Effects of maternal gestational diet, with or without methionine, on muscle transcriptome of Bos indicus-influenced beef calves following a vaccine-induced immunological challenge
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24. Myostatin propeptide mutation of the hypermuscularCompactmice decreases the formation of myostatin and improves insulin sensitivity
    Tamás Kocsis, György Trencsényi, Kitti Szabó, Júlia Aliz Baán, Géza Müller, Luca Mendler, Ildiko Garai, H. Reinauer, Ferenc Deak, A László et al. · 2016 · American Journal of Physiology-Endocrinology and Metabolism
25. Review of the health-promoting effects of exercise and the involvement of myokines.
    Kazuhiro Nishii, Naoki Aizu, Kouji Yamada · 2023 · PubMed Central
26. Heat stress decreased hair follicle population in rex rabbits
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27. SMAD4 contributes to chondrocyte and osteocyte development
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28. Smad8 Is Increased in Duchenne Muscular Dystrophy and Suppresses miR-1, miR-133a, and miR-133b
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29. GDF5 as a rejuvenating treatment for age-related neuromuscular failure
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30. Maternal supplementation with mulberry-leaf flavonoids improves the development of skeletal muscle in the offspring of chickens
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31. Decorin, an exercise-induced secretory protein, is associated with improved prognosis in breast cancer patients but does not mediate anti-tumorigenic tissue crosstalk in mice
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32. Bone morphogenetic protein-induced heterotopic bone formation: What have we learned from the history of a half century?
    Takenobu Katagiri, Kenji Osawa, Sho Tsukamoto, Mai Fujimoto, Arei Miyamoto, Takato Mizuta · 2014 · Japanese Dental Science Review
33. AR cooperates with SMAD4 to maintain skeletal muscle homeostasis
    Mitra Forouhan, Wooi Fang Lim, Laura C. Zanetti-Domingues, Christopher J. Tynan, Thomas C. Roberts, Bilal Ahmad Malik, Raquel Manzano, Alfina A. Speciale, Ruth Ellerington, Antonio Garcia-Guerra et al. · 2022 · Acta Neuropathologica
34. Associations between allelic polymorphism of the BMP Binding Endothelial Regulator and phenotypic variation of cattle
    Chunping Zhao, Linsheng Gui, Yaokun Li, Martin Wolfgang Plath, Linsen Zan · 2015 · Molecular and Cellular Probes
35. Bone morphogenetic protein signaling in rotator cuff muscle atrophy and fatty infiltration
    Xuhui Liu · 2015 · Muscles Ligaments and Tendons Journal
36. FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy
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37. The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass
    Catherine E. Winbanks, Justin L. Chen, Hongwei Qian, Yingying Liu, Bianca C. Bernardo, Claudia Beyer, Kevin I. Watt, Rachel E. Thomson, Timothy Connor, Bradley J. Turner et al. · 2013 · The Journal of Experimental Medicine
38. Pharmacology of manipulating lean body mass
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39. Actions from head to toe: An update on Bone/Body Morphogenetic Proteins in health and disease
    Christian Hiepen, David Yadin, Paul Rikeit, Gina Dörpholz, Petra I. Knaus · 2016 · Cytokine & Growth Factor Reviews
40. Bone morphogenetic protein signaling in vertebrate motor neurons and neuromuscular communication
    Nelson Osses, Juan Pablo Henríquez · 2015 · Frontiers in Cellular Neuroscience
41. Association of growth performance and body conformational traits with BMP4 gene variation in Barki lambs
    Adel H. M. Ibrahim · 2019 · Growth Factors
42. Exploration of the core gene signatures and mechanisms between NAFLD and sarcopenia through transcriptomic level
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43. Network model of skeletal muscle cell signalling predicts differential responses to endurance and resistance exercise training
    Annabelle Fowler, Katherine R. Knaus, Stephanie Khuu, Ali Khalilimeybodi, Simon Schenk, Samuel R. Ward, Andrew C. Fry, Padmini Rangamani, Andrew D. McCulloch · 2024 · Experimental Physiology
44. Building Haplotype‐Resolved 3D Genome Maps of Chicken Skeletal Muscle
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45. Therapeutic strategies to modulate gut microbial health: Approaches for sarcopenia management.
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46. Self-Assembling Injectable Hydrogel for Controlled Drug Delivery of Antimuscular Atrophy Drug Tilorone
    Mohamed M. Abdelghafour, Ágota Deák, T. Kiss, Mária Budai-Szűcs, Gábor Katona, Rita Ambrus, Bálint Lőrinczi, Anikó Keller-Pintér, István Szatmári, Diána Szabó et al. · 2022 · Pharmaceutics
47. BMP9 functions as a negative regulator in the myogenic differentiation of primary mouse myoblasts
    Xiya Lu, Liang Li, Nanhui Wu, Wenjuan Chen, Hong Sheng, Mingyuan Xu, Yangfeng Ding, Yunlu Gao · 2023 · Bioscience Biotechnology and Biochemistry
48. The miR-567/RPL15/TGF-β/Smad axis inhibits the stem-like properties and chemo-resistance of gastric cancer cells
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49. Emerging role of TAK1 in the regulation of skeletal muscle mass
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50. An observational human study investigating the effect of anabolic androgenic steroid use on the transcriptome of skeletal muscle and whole blood using RNA-Seq
    Alexander Kolliari-Turner, Giscard Humberto Oliveira Lima, Guan Wang, Fernanda Rossell Malinsky, Antonia Karanikolou, Gregor Eichhorn, Kumpei Tanisawa, Jonathan A. Ospina Betancurt, Blair Hamilton, Paulette Y. O. Kumi et al. · 2023 · BMC Medical Genomics
51. ActRII or BMPR ligands inhibit skeletal myoblast differentiation, and BMPs promote heterotopic ossification in skeletal muscles in mice
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52. Immunosenescence in skeletal muscle: The role-play in cancer cachexia chessboard
    Matteo Giovarelli, Emanuele Mocciaro, Carla Carnovale, Davide Cervia, Cristiana Perrotta, Emilio Clementi · 2025 · Seminars in Cancer Biology
53. The quasi-parallel lives of satellite cells and atrophying muscle
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54. Impact of long‐lasting spontaneous physical activity on bone morphogenetic protein 4 in the heart and tibia in murine model of heart failure
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55. Insights into the bone morphogenetic protein signaling in musculoskeletal disorders: Mechanisms and crosstalk
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56. RNA signaling in skeletal muscle: the central role of microRNAs and exosomal microRNAs
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57. SMAD6 overexpression leads to accelerated myogenic differentiation of LMNA mutated cells
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58. The peripheral tumor neuro-microenvironment: Deciphering neural landscape and mechanistic insights for therapeutic innovation
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59. Molecular communication from bone to skeletal muscle: an overview
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60. Therapeutic targeting of GDF11 in muscle atrophy: Insights and strategies
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61. Induction of ATF4-Regulated Atrogenes Is Uncoupled from Muscle Atrophy during Disuse in Halofuginone-Treated Mice and in Hibernating Brown Bears
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62. Genetic variants of the BMP2 and GDF9 genes and their associations with reproductive performance traits in Barki ewes
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63. Pancreatic cancer cachexia: A systemic consequence of multi-organ interactions
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64. Identification of novel macrophages and bone morphogenetic protein signals causing ectopic calcification and impairing muscle regeneration
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65. Skeletal muscle memory: implications for sports, aging and nutrition
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66. Unresolved intramuscular inflammation, not diminished skeletal muscle regenerative capacity, is at the root of rheumatoid cachexia: insights from a rat CIA model
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67. Targeting activins and inhibins to treat reproductive disorders and cancer cachexia
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68. Skeletal Muscle in Spinal Muscular Atrophy As an Opportunity for Therapeutic Intervention
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69. Cellular mechanisms promoting cachexia and how they are opposed by sirtuins
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70. Metabolic adaptation and fragility in healthy 3D in vitro skeletal muscle tissues exposed to chronic fatigue syndrome and Long COVID-19 sera
    Sheeza Mughal, Félix Andújar-Sánchez, María Sabater-Arcis, Glòria Garrabou, Joaquim Fernández‐Solà, José Alegre, Ramon Sanmartin Sentañes, Jesús Castro‐Marrero, Anna Esteve‐Codina, Eloi Casals et al. · 2025 · Biofabrication
71. Molecular Characterization and Function of Bone Morphogenetic Protein 7 (BMP7) in the Pacific Abalone, Haliotis discus hannai
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72. A molecular systems architecture of neuromuscular junction in amyotrophic lateral sclerosis
    V. A. Shiva Ayyadurai, Prabhakar Deonikar, Roger Dale Kamm · 2025 · npj Systems Biology and Applications
73. Tumours block protective muscle and nerve signals to cause cachexia
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74. mTORC1 and BMP-Smad1/5 regulation of serum-stimulated myotube hypertrophy: a role for autophagy
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75. BMP10 positively regulates myogenic differentiation in C2C12 myoblasts via the Smad 1/5/8 signaling pathway
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76. Single‐nucleus transcriptomics reveals subsets of degenerative myonuclei after rotator cuff tear‐induced muscle atrophy
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77. Nutritional strategies against skeletal muscle wasting in cancer-associated cachexia: the role of β-hydroxybutyrate and polyunsaturated fatty acids
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78. BMP Signaling Is a Prognostic Marker in Patients With Colorectal Cancer and Associates With Frailty
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79. Petri net-based prediction of therapeutic targets that recover abnormally phosphorylated proteins in muscle atrophy
    Jin‐Myung Jung, Mijin Kwon, Sunghwa Bae, Soorin Yim, Doheon Lee · 2018 · BMC Systems Biology
80. p21-Activated Kinase 1 Is Permissive for the Skeletal Muscle Hypertrophy Induced by Myostatin Inhibition
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81. Effect of genetic variants in the SMAD1 and SMAD5 genes promoter on growth and beef quality traits in cattle
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82. Motoneuron-derived Activinβ regulates Drosophila body size and tissue-scaling during larval growth and adult development
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83. Integrated transcriptome and metabolome analysis of E17 embryonic pectoral muscle development regulated by 1 % CO2 during the first 10 days of incubation
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84. Altered H19/miR‐675 expression in skeletal muscle is associated with low muscle mass in community‐dwelling older adults
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85. Role of circadian clock system in the mitochondrial trans-sulfuration pathway and tissue remodeling
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86. Loss of BMPR2 leads to high bone mass due to increased osteoblast activity
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87. The Effect of Uphill and Downhill Exercise Training on Myogenic Mechanism of Wnt/BMP Signaling in the Skeletal Muscle of Aged Rats
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88. Therapeutic Benefit in Rheumatoid Cachexia Illustrated Using a Novel Primary Human Triple Cell Coculture Model
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89. Identification of dysregulated canonical pathways associated with pathogenesis and progression of Amyotrophic Lateral Sclerosis—An integrated bioinformatics approach
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90. GDF5
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91. Exploring lncRNA-Mediated Mechanisms in Muscle Regulation and Their Implications for Duchenne Muscular Dystrophy
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92. GDF5 modulation of MuSC pool as a potential therapeutic benefit for DMD
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93. Weighted Single-Step Genome-Wide Association Study Identifies Candidate Genes for Carcass Traits and Primal Cut Yields in Hanwoo Cattle
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94. A single‐nucleus chromatin accessibility atlas reveals epigenetic dynamics in aging mouse skeletal muscle
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95. Stimulation of Adult Muscle Stem Cells with BMPs Results in Direct Activation of Notch Pathway Genes
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96. Hyperactivation of Transforming Growth Factor-β–Activated Kinase 1 Causes Skeletal Muscle Pathology Reminiscent of Inflammatory Myopathies
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97. The Bioengineering of Exogenic Organs and/or Cells for Use in Regenerative Medicine
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98. Glia-neuron signaling mediated by two different BMP ligands impacts synaptic growth
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99. The function of TGF-beta1 in ICUAW and the characterization of Sfrp2, a TGF-beta1 target, in skeletal muscle atrophy
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100. TNF-like weak inducer of apoptosis (TWEAK) : not so weak after all.
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