A PP2A-B55 recognition signal controls substrate dephosphorylation kinetics during mitotic exit

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Items 101–193 of 193

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3. Protein Phosphatases in G1 Regulation
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4. The role of serine/threonine phosphatases in human development: Evidence from congenital disorders
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6. Phosphatase specificity influences phosphorylation timing of CDK substrates during the cell cycle
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7. Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae
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8. The diverging role of CDC14B: from mitotic exit in yeast to cell fate control in humans
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9. CDK1-PP2A-B55 interplay ensures cell cycle oscillation via Apc1-loop300
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10. Clinical Potential of Misshapen/NIKs-Related Kinase (MINK) 1—A Many-Sided Element of Cell Physiology and Pathology
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11. Requirement of PP2A-B56Par1 for the Stabilization of the CDK Inhibitor Rum1 and Activation of APC/CSte9 during Pre-Start G1 in S. pombe
    Vilte Stonyte, Ruth Martín, Dario Segura-Peña, Nikolina Sekulić, Sandra López‐Avilés · 2020 · iScience
12. Molecular mechanism of PP2A/B55α phosphatase inhibition by IER5
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13. Biochemical characterization of the Eya and PP2A-B55α interaction
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14. Ppp2r1a haploinsufficiency increases excitatory synaptic transmission and decreases spatial learning by impairing endocannabinoid signaling
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15. Roles of constitutive and signal-dependent protein phosphatase 2A docking motifs in burst attenuation of the cyclic AMP response element-binding protein
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16. PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling
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17. Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae.
    Jasmin Philip, Mihkel Örd, Andriele Silva, Shaneen M Singh, John F.X. Diffley, Dirk Remus, Mart Loog, Amy E. Ikui · 2022 · CUNY Academic Works (City University of New York)
18. Mitotic exit: Determining the PP2A dephosphorylation program
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19. Differential Expression of Genes for Ubiquitin Ligases in Medulloblastoma Subtypes
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20. Spatiotemporal coordination of Greatwall-Endos-PP2A promotes mitotic progression
    Myreille Larouche, David Kachaner, Peng Wang, Karine Normandin, Damien Garrido, Changfu Yao, Maxime Cormier, Kristen M. Johansen, Jørgen Johansen, Vincent Archambault · 2021 · The Journal of Cell Biology
21. Induction of a Spindle-Assembly-Competent M Phase in Xenopus Egg Extracts
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22. Defining the Protein Phosphatase 2A (PP2A) Subcomplexes That Regulate FoxO Transcription Factor Localization
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23. Decoding Cdk1 control: from mitotic thresholds to meiotic specificity
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24. SILAC kinase screen identifies potential MASTL substrates
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25. Protein Phosphatase 2A as a Therapeutic Target in Pulmonary Diseases
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26. The cell cycle oscillator and spindle length set the speed of chromosome separation in Drosophila embryos
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27. Nucleo-cytoplasmic trafficking regulates nuclear surface area during nuclear organogenesis
    Vincent Boudreau, James W. Hazel, Jake Sellinger, Pan Chen, Kathryn Manakova, Rochelle Radzyminski, Hernán G. García, Jun F. Allard, Jesse C. Gatlin, Paul S. Maddox · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
28. Kinases/Phosphatases | Serine/Threonine Protein Phosphatases
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29. PP2A-B55 phosphatase counteracts Ki-67-dependent chromosome individualization during mitosis
    María Sanz‐Flores, Miguel Ruiz‐Torres, Cristina Aguirre‐Portolés, Aicha El Bakkali, Beatriz Salvador-Barberó, Carolina Villarroya‐Beltri, Sagrario Ortega, Diego Megı́as, Daniel W. Gerlich, Mónica Álvarez‐Fernández et al. · 2024 · Cell Reports
30. The balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells
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31. Roles of phosphatases in eukaryotic DNA replication initiation control
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32. Cell Cycle–Specific Protein Phosphatase 1 (PP1) Substrates Identification Using Genetically Modified Cell Lines
    Dorothee C Kommer, Konstantinos Stamatiou, Paola Vagnarelli · 2024 · Methods in molecular biology
33. PP2A-B55SUR-6 promotes nuclear envelope breakdown in C. elegans embryos
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34. Transitions in the proteome and phospho-proteome during Xenopus laevis development
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35. Spindle checkpoint signalling in anaphase is prevented by KNL1 release from kinetochores
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36. The silent players: Atypical BCR‑ABL isoforms as biomarkers and therapeutic hurdles in CML pathogenesis (Review)
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37. Transitions in the proteome and phospho-proteome during Xenopus laevis development
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38. Houge-Janssens syndrome
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39. Cell Cycle: Abrogating Interphase/M Phase Bistability
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40. Gradual Compaction of the Central Spindle Decreases its Dynamicity as Revealed in PRC1 and EB1 Gene-Edited Human Cells
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41. PP2A-B56 regulates Mid1 protein levels for proper cytokinesis in fission yeast
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42. CDK1-dependent N-terminal NuMA phosphorylation promotes dynein-dynactin-NuMA assembly for accurate chromosome segregation
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43. Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption
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44. Site-specific phosphorylation of ZYG-1 regulates ZYG-1 stability and centrosome number
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45. Global substrate identification and high throughput in vitro dephosphorylation reactions uncover PP1 and PP2A-B55 specificity principles
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46. Phosphatase and Kinase Substrate Specificity Profiling with Pooled Synthetic Peptides and Mass Spectrometry
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47. Proteome-wide forced interactions reveal a functional map of cell-cycle phospho-regulation in S. cerevisiae
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48. Combination of in vivo and in vitro phosphoproteomics determines the PP2A target repertoire on proteome scale
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49. Protein phosphatase 2A subunit B55 alpha is required for angiotensin type 2 receptor elicited natriuresis
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50. FAM122A inhibition of PP2A-B55 through a bipartite binding mechanism
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51. TBX1 suppresses colorectal cancer cells via PPP2R2B-mediated inhibition of MAPK/ERK and PI3K/AKT pathways
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52. CDK1-Cyclin B mediated phosphorylation of PP2A-B56 on B56Par1.T73T75 controls mitotic entry timing and Schizosaccharomyces pombe cell size
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53. Protocol to assess substrate dephosphorylation by serine/threonine phosphoprotein phosphatases in vitro
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54. GPSD: a hybrid learning framework for the prediction of phosphatase-specific dephosphorylation sites
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55. Multi-omic analyses reveal a differential contribution of chromatin-associated PP1 holoenzymes to mitotic exit and G1 re-establishment
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56. The regulatory subunit phr2AB of Dictyostelium discoideum phosphatase PP2A interacts with the centrosomal protein CEP161, a CDK5RAP2 ortholog
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57. Use of Mitotic Protein Kinase Inhibitors and Phospho-Specific Antibodies to Monitor Protein Phosphorylation During the Cell Cycle
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58. Transitions in the Proteome and Phospho-Proteome During Xenopus laevis Development
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59. Serine/Threonine-Protein Phosphatase 2A
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60. Analisis funcional de PP2AB55 en ciclo celular, autofagia y transcripcion
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61. In Cellulo Kinase Screen Identifies Potential MASTL Substrates
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62. The Greatwall-Endosulfine-PP2A/B55 pathway in Schizosaccharomyces pombe: regulatory mechanisms and roles in cell differentiation and ageing
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63. A PP4 foszfatáz kölcsönható partnereinek azonosítása és szubsztrátum-felismerő mechanizmusának feltárása
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64. Faculty Opinions recommendation of Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits.
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65. Faculty Opinions recommendation of MAD1-dependent recruitment of CDK1-CCNB1 to kinetochores promotes spindle checkpoint signaling.
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66. Serine/Threonine-Protein Phosphatase 2A
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67. TBX1 functions as a tumor suppressor in colorectal cancer by PPP2R2B-mediated the inhibition of MAPK/ERK and PI3K/AKT signaling pathways
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70. PP2A-B55α,δ phosphatase counteracts Ki67-dependent chromosome individualization during mitosis
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74. PP2A-Tws dephosphorylates Map205, is required for Polo localization to microtubules and promotes cytokinesis in Drosophila
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75. PP2A-B56α is a key determinant of cardiac protein phosphorylation and functional responses to β-adrenergic signalling
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79. Loss of T73T75 phosphorylation on PP2A-B56 Par1 advances mitotic entry and reduces S. pombe cell size
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81. Switching of the c-Myc protein degradation pathway depending on the PP2A-B55α complex levels
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84. Contrôle de l’entrée en division méiotique par les enzymes PKA et PP2A, et leur substrat Arpp19
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86. Exploring the phosphoproteome landscape at the transition from the first to the second meiotic division
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87. Mechanistic insights into macromolecular recognition at the PP2A-B55α regulatory groove from structure-based modeling and molecular dynamics
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88. A case report of a novel de novo variant in PPP2CA causing a neurodevelopmental disorder and epilepsy
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89. Set mediates chromosome alignment and Cohesin cleavage independently of direct PP2A-B56-binding in oocyte meiosis
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