The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
CARTILAGE RESORPTION IN THE TIBIAL EPIPHYSEAL PLATE OF GROWING RATS
Open accessAbstract
An electron microscopic study of the tibial epiphyseal plates of growing rats reveals that the resorption of unmineralized and mineralized cartilage occurs by two different mechanisms. During resorption the unmineralized transverse cartilaginous walls between chondrocytes are invaded by capillary sprouts. At the resorption zone, numerous cytoplasmic processes derived primarily from the perivascular cells and, to a lesser extent, from the endothelial cells of the sprouts penetrate and appear to lyse the unmineralized transverse cartilaginous walls. Hydrolases released from the degenerating chondrocytes and/or capillary sprouts may also participate in this process. The second resorption mechanism involves the mineralized longitudinal cartilaginous septa. Resorption of these septa is mediated by chondroclasts whose fine structure is identical with that of osteoclasts. The active surface of the chondroclasts has a ruffled border. The surface membrane of the chondroclasts is relatively smooth on either side of the ruffled border and lies in direct apposition with the underlying mineralized cartilage. This observation suggests that the microenvironment in the zone of resorption may be maintained by the neighboring unruffled surfaces of the chondroclasts, which thus seal off and segregate the active portions of these cells.
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Cites
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Self-citationElectron microscopy of the epiphyseal apparatus
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Cited by
VESICLES ASSOCIATED WITH CALCIFICATION IN THE MATRIX OF EPIPHYSEAL CARTILAGE
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Metadata
- Authors
- Schenk, R. K., Spiro, D., & Wiener, J.
- Venue
- The Journal of Cell Biology
- Publisher
- Rockefeller University Press
- Published
- 1967-07-01
- Volume
- 34
- Issue
- 1
- Pages
- 275-291
- ISSN
- 0021-9525 (ISSN-L)
- 1540-8140
- OpenAlex
- W2058844752
- Cited by
- 268
- References
- 22
- FWCI
- 10.65
- Type
- journal article
- Language
- en
- Open access
- green
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- Schenk, R. K., Spiro, D., & Wiener, J. (1967). CARTILAGE RESORPTION IN THE TIBIAL EPIPHYSEAL PLATE OF GROWING RATS. The Journal of Cell Biology. https://doi.org/10.1083/jcb.34.1.275
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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