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Cited by 353

The DOI matches its Crossref record.

The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor.

Open access
Postlethwaite, A E, Snyderman, R, Kang, A H·1976·The Journal of experimental medicine
DOI 10.1084/jem.144.5.1188
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Abstract

A quantitative assay that measures fibroblast chemotaxis in vitro is described. Application of this technique has revealed that peripheral blood lymphocytes stimulated by antigen or mitogen in vitro produce a factor that is chemotactic for human dermal fibroblasts. This lymphocyte-derived chemotactic factor for fibroblasts (LDCF-F) is different from the lymphokine that is chemotactic for monocytes or macrophages. Macrophages are required for the generation of LDCF-F by T lymphocytes stimulated by phytohemagglutinin. The fibroblast chemotactic factor is heat stable (56 degrees C for 30 min), trypsin sensitive, and neuraminidase resistant. LDCF-F could function to attact connective tissue fibroblasts to sites at which cell-mediated immune reactions are occurring in vivo.

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Metadata

Authors
Postlethwaite, A. E., Snyderman, R., & Kang, A. H.
Venue
The Journal of experimental medicine
Publisher
Rockefeller University Press
Published
1976-11-01
Volume
144
Issue
5
Pages
1188-1203
ISSN
  • 0022-1007 (ISSN-L)
  • 1540-9538
DOI
10.1084/jem.144.5.1188
OpenAlex
W2121844839
Cited by
353
References
0
FWCI
5.73
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor. https://app.cochat.ai/papers/10.1084/jem.144.5.1188
The paper
Postlethwaite, A. E., Snyderman, R., & Kang, A. H. (1976). The chemotactic attraction of human fibroblasts to a lymphocyte-derived factor. The Journal of experimental medicine. https://doi.org/10.1084/jem.144.5.1188

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.