Correction of the Iron Overload Defect in β-2-Microglobulin Knockout Mice by Lactoferrin Abolishes Their Increased Susceptibility to Tuberculosis
Schaible, Ulrich E., Collins, Helen L., Priem, Friedrich, Kaufmann, Stefan H.E.·2002·The Journal of Experimental Medicine
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- Mycobacterium tuberculosisand His ComradesUlrich Emil Schaible · 2009 · Wiley eBooks
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- Tuberculosis susceptibility – implications for drug development and therapyNoel J C Snell · 2003 · Expert Opinion on Pharmacotherapy
- 3. Iron and Inflammation.Hideo Harigae · 2010 · Nihon Naika Gakkai Zasshi
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- Comparison of DNA delivery systems for vaccination against intracellular bacteriaKim, Nayoung · 2004
- Benefits of safety belt use well proven.H A Muller · 1988 · PubMed
- Structural Biology of Chronic Inflammation-Associated Signalling Pathways: Toward Structure-Guided Drug DevelopmentReiya Taniguchi, Osamu Nureki · 2016 · Springer eBooks
- Is Iron Overload a Risk Factor for Mycobacterium Tuberculosis and a Potential Target of Therapy?Kamal Shemisa · 2017 · Journal of Microbiology & Experimentation
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- Genomic Approaches to Characterization of the Innate Immune Response of Catfish to Bacterial InfectionEric Peatman · 2007
- Role of Innate Immunity in Bacterial InfectionPeter J. Seiler, Ulrich Steinhoff, Stefan H. E. Kaufmann · 2014 · ASM Press eBooks
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