The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo
Open accessAbstract
Regulatory T (T reg) cells exert powerful down-modulatory effects on immune responses, but it is not known how they act in vivo. Using intravital two-photon laser scanning microscopy we determined that, in the absence of T reg cells, the locomotion of autoantigen-specific T cells inside lymph nodes is decreased, and the contacts between T cells and antigen-loaded dendritic cells (DCs) are of longer duration. Thus, T reg cells can exert an early effect on immune responses by attenuating the establishment of stable contacts during priming of naive T cells by DCs.
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Cites
Sakaguchi, S. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141122 · Cited by 3,306
T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
Mempel, T. R., Henrickson, S. E., & von Andrian, U. H. (2004) · Nature · doi:10.1038/nature02238 · Cited by 1,714
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
Thornton, A. M., & Shevach, E. M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.164.1.183 · Cited by 1,229
Visualizing dendritic cell networks in vivo
Lindquist, R. L., Shakhar, G., Dudziak, D., Wardemann, H., Eisenreich, T., Dustin, M. L., & Nussenzweig, M. C. (2004) · Nature Immunology · doi:10.1038/ni1139 · Cited by 808
Self-citationVisualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
Tang, Q., Adams, J. Y., Tooley, A. J., Bi, M., Fife, B. T., Serra, P., Santamaria, P., Locksley, R. M., Krummel, M. F., & Bluestone, J. A. (2006) · Nature Immunology · doi:10.1038/ni1289 · Cited by 774
Dynamic Imaging of T Cell-Dendritic Cell Interactions in Lymph Nodes
Stoll, S., Delon, J., Brotz, T. M., & Germain, R. N. (2002) · Science · doi:10.1126/science.1071065 · Cited by 718
Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes
Bousso, P., & Robey, E. (2003) · Nature Immunology · doi:10.1038/ni928 · Cited by 625
Interleukin 2 Signaling Is Required for CD4+ Regulatory T Cell Function
Furtado, G. C., de Lafaille, M. A. C., Kutchukhidze, N., & Lafaille, J. J. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020190 · Cited by 625
Self-citationImaging the Single Cell Dynamics of CD4+ T Cell Activation by Dendritic Cells in Lymph Nodes
Miller, M. J., Safrina, O., Parker, I., & Cahalan, M. D. (2004) · The Journal of Experimental Medicine · doi:10.1084/jem.20041236 · Cited by 545
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Cited by
Vignali, D. A. A., Collison, L. W., & Workman, C. J. (2008) · Nature Reviews Immunology · doi:10.1038/nri2343 · Cited by 3,463
Regulatory T cells: mechanisms of differentiation and function
Josefowicz, S. Z., Lu, L.-F., & Rudensky, A. Y. (2012) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141623 · Cited by 2,866
The PD‐1 pathway in tolerance and autoimmunity
Francisco, L. M., Sage, P. T., & Sharpe, A. H. (2010) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00923.x · Cited by 2,300
Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity
Griffith, J. W., Sokol, C. L., & Luster, A. D. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120145 · Cited by 2,059
Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression
Shevach, E. M. (2009) · Immunity · doi:10.1016/j.immuni.2009.04.010 · Cited by 1,754
Metadata
- Authors
- Tadokoro, C. E., Shakhar, G., Shen, S., Ding, Y., Lino, A. C., Maraver, A., Lafaille, J. J., & Dustin, M. L.
- Venue
- The Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 2006-03-13
- Volume
- 203
- Issue
- 3
- Pages
- 505-511
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2125921975
- Cited by
- 527
- References
- 26
- FWCI
- 18.85
- Type
- journal article
- Language
- en
- Open access
- green
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- Tadokoro, C. E., Shakhar, G., Shen, S., Ding, Y., Lino, A. C., Maraver, A., Lafaille, J. J., & Dustin, M. L. (2006). Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo. The Journal of Experimental Medicine. https://doi.org/10.1084/jem.20050783
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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