Human monocytes and macrophages regulate immune tolerance via integrin αvβ8–mediated TGFβ activation
Kelly, Aoife, Gunaltay, Sezin, McEntee, Craig P., Shuttleworth, Elinor E., Smedley, Catherine, Houston, Stephanie A., Fenton, Thomas M., Levison, Scott +2 more·2018·Journal of Experimental Medicine
Cited by (124)
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- A subset of CD4+ effector memory T cells limit immunity to pulmonary viral infection and prevent tissue pathology via activation of latent TGFβCraig P. McEntee, Stephanie A. Houston, Conor M. Finlay, S Rossi, Guangyan Liu, Tovah N. Shaw, Joshua Casulli, Mark E. Fife, Catherine Smedley, TS Griffith et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
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- La citocina TGF-β y su papel en la comunicación intercelular en el microambiente tumoral: Mecanismos de síntesis, secreción, activación y acciónChristian Daniel Meza-Juárez, Víctor Manuel Color-Aparicio, Ángeles C. Tecalco-Cruz, Marina Macías‐Silva · 2025 · TIP Revista Especializada en Ciencias Químico-Biológicas
- Time-dependent changes in monocyte subsets and gene expression patterns are associated with long-term recovery in patients with ischemic strokeJuliane Tampé, Emanuela Monni, Yu-Ping Shen, Sara Palma-Tortosa, Emil Brogårdh, Arne G. Lindgren, Zaal Kokaia · 2026 · Research Square
- Control of adaptive immune responses by the TGFβ-activating avb8 integrins - implications for mucosal immune homeostasis and humoral immunitySébastien This · 2020 · theses.fr (ABES)
- Etude de l’influence du TGF-β sur les sous-populations de fibroblastes associés au cancer et leur implication pronostique dans les cancers du pancréasAngélique Vienot · 2021 · theses.fr (ABES)
- Exploring the interplay between chronic thrombo-inflammation and megakaryopoiesis in the development of microvascular lesions during vasculitis-associated glomerulonephritisMélodie Douté · 2023
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- Circumventing Ewing sarcoma tumor microenvironment resistance by IL1RAP CAR-modified TGFβ1-imprinted natural killer cells in combination with IL-15 agonist and anti-GD2 antibodyWen Luo, Haitao Zhang, W Li, Changxin Xu, Hongwen Zhu, Marcelo de Souza Fernandes Pereira, Justin M. Lyberger, Shiori Eguchi, Yanling Liao, Jeremy Rosenblum et al. · 2026 · Journal for ImmunoTherapy of Cancer
- Inhibition of integrin αvβ8-mediated TGFβ activation and active-TGFβ blockade promote anti-tumor immunity through distinct biological mechanismsKate Williams, Stephanie Mittman, Natalie S. Firmino, Jasmine W. Larrick, Zhe Zhang, Caroline Whitty, Hsiao‐Yen Ma, Xin Ren, Cecilia Chiu, Yagai Yang et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Multifunctional nucleic acid-based therapy in fibrosis-related diseasesJunxin Cheng, Mi Zhou, Yalei Guo, Yiyan Yang, Weitong Lv, Renzeng YANG, Yuting Xie, Yueying Jiang, Lan Yao, Cai Qi et al. · 2026 · Science China Chemistry
- Inflammation identity crisis: pathogenic nature of platelet-derived transforming growth factor β in chronic inflammatory conditionsKarli R. Sutton, Rachel C. Eisenhart, Meera Vir Singh · 2026 · Frontiers in Immunology
- An MMP-14/STAT3 feedback loop upregulates PD-L1 to drive immunosuppression and tumorigenesis in bladder cancerShuai Zhu, Lisa Köhler, Bettina Ergün, David Meierhofer, Jonas Felix Busch, Anja Rabien · 2026 · iScience