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Cited by 236

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CARBOHYDRATE HISTOCHEMISTRY STUDIED BY ACETYLATION TECHNIQUES

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McManus, J. F. A., Cason, Jane E.·1950·Journal of Experimental Medicine

Abstract

An acetic anhydride pyridine mixture acetylates hydroxyl groups in tissue sections. The acetyl groups can be removed from tissue sections by weak alkali. Sections acetylated by acetic anhydride pyridine no longer produce aldehydes after oxidation by periodic acid. Acetylated sections subjected to weak alkali regain the ability to produce aldehydes after oxidation by periodic acid. Acetylation of tissue sections and the removal of acetyl groups by weak alkali can be used as histochemical confirmation of the carbohydrate nature of materials coloring with Schiff's reagent after periodic acid.

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Metadata

Authors
McManus, J. F. A., & Cason, J. E.
Venue
Journal of Experimental Medicine
Published
1950-06-01
Volume
91
Issue
6
Pages
651-654
ISSN
  • 0022-1007 (ISSN-L)
  • 1540-9538
OpenAlex
W2053543375
Cited by
236
References
0
FWCI
18.35
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: CARBOHYDRATE HISTOCHEMISTRY STUDIED BY ACETYLATION TECHNIQUES. https://app.cochat.ai/papers/10.1084/jem.91.6.651
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McManus, J. F. A., & Cason, J. E. (1950). CARBOHYDRATE HISTOCHEMISTRY STUDIED BY ACETYLATION TECHNIQUES. Journal of Experimental Medicine. https://doi.org/10.1084/jem.91.6.651

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.