The DOI matches its Crossref record.
Human Immunodeficiency Virus Load in Breast Milk, Mastitis, and Mother‐to‐Child Transmission of Human Immunodeficiency Virus Type 1
Abstract
Human immunodeficiency virus (HIV) type 1 load in breast milk and mastitis were examined as risk factors for vertical transmission of HIV-1. Six weeks after delivery, HIV-1 load and sodium (an indicator of mastitis) were measured in breast milk from 334 HIV-1-infected women in Malawi. Median breast milk HIV-1 load was 700 copies/mL among women with HIV-1-infected infants versus undetectable (<200 copies/mL) among those with uninfected infants, respectively (P<. 0001). Elevated breast milk sodium levels consistent with mastitis occurred in 16.4% of HIV-1-infected women and were associated with increased vertical transmission of HIV-1 (P<.0001). Median breast milk HIV-1 load was 920 copies/mL among women with versus undetectable among those without elevated breast milk sodium levels, respectively (P<.0001). Mastitis and breast milk HIV-1 load may increase the risk of vertical transmission of HIV-1 through breast-feeding.
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Citations
Cited by
Iliff, P. J., Piwoz, E. G., Tavengwa, N. V., Zunguza, C. D., Marinda, E. T., Nathoo, K. J., Moulton, L. H., Ward, B. J., & Humphrey, J. H. (2005) · AIDS · doi:10.1097/01.aids.0000166093.16446.c9 · Cited by 573
Transmission of Macrophage‐Tropic HIV‐1 by Breast‐Milk Macrophages via DC‐SIGN
Satomi, M., Shimizu, M., Shinya, E., Watari, E., Owaki, A., Hidaka, C., Ichikawa, M., Takeshita, T., & Takahashi, H. (2005) · The Journal of Infectious Diseases · doi:10.1086/426829 · Cited by 54
Metadata
- Authors
- Semba, R. D., Kumwenda, N., Hoover, D. R., Taha, T. E., Quinn, T. C., Mtimavalye, L., Biggar, R. J., Broadhead, R., Miotti, P. G., Sokoll, L. J., van der Hoeven, L., & Chiphangwi, J. D.
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-07
- Volume
- 180
- Issue
- 1
- Pages
- 93-98
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2166583938
- Cited by
- 383
- References
- 0
- FWCI
- 23.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Human Immunodeficiency Virus Load in Breast Milk, Mastitis, and Mother‐to‐Child Transmission of Human Immunodeficiency Virus Type 1. https://app.cochat.ai/papers/10.1086/314854
- The paper
- Semba, R. D., Kumwenda, N., Hoover, D. R., Taha, T. E., Quinn, T. C., Mtimavalye, L., Biggar, R. J., Broadhead, R., Miotti, P. G., Sokoll, L. J., van der Hoeven, L., & Chiphangwi, J. D. (1999). Human Immunodeficiency Virus Load in Breast Milk, Mastitis, and Mother‐to‐Child Transmission of Human Immunodeficiency Virus Type 1. The Journal of Infectious Diseases. https://doi.org/10.1086/314854
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
