The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Background and Current Knowledge of Chlamydia pneumoniae and Atherosclerosis
Abstract
Attributes of Chlamydia pneumoniae of potential importance to a relationship with atherosclerosis are described. Among these are that C. pneumoniae is not new. It is unique. It is a pathogen with which everyone is infected, and it is difficult to treat. It causes immunopathology, myocarditis, and endocarditis and chronicity is a hallmark of Chlamydia infection. Current knowledge of the relation of C. pneumoniae and atherosclerosis comes from observational (e.g., seroepidemiology and tissue studies) and experimental studies. The limitations of the serologic studies of chronic infection are noted as is the conclusive demonstration of an association of C. pneumoniae and atherosclerosis by the repeated and frequent finding of the organism in atherosclerotic tissue. Experimental studies are needed to determine if the association is causal. Such studies should include animal models, basic mechanisms, and secondary prevention antibiotic treatment trials.
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Citations
Cites
Atherosclerosis--an inflammatory disease
Ross, R. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901143400207 · Cited by 21,725
Cited by
Myeloperoxidase: friend and foe
Klebanoff, S. J. (2005) · Journal of Leukocyte Biology · doi:10.1189/jlb.1204697 · Cited by 2,282
Age-related inflammatory cytokines and disease
Brüünsgaard, H., & Pedersen, B. K. (2003) · Immunology and Allergy Clinics of North America · doi:10.1016/s0889-8561(02)00056-5 · Cited by 608
Immunity to Murine Chlamydial Genital Infection
Morrison, R. P., & Caldwell, H. D. (2002) · Infection and Immunity · doi:10.1128/iai.70.6.2741-2751.2002 · Cited by 411
Azithromycin for the Secondary Prevention of Coronary Events
Grayston, J. T., Kronmal, R. A., Jackson, L. A., Parisi, A. F., Muhlestein, J. B., Cohen, J. D., Rogers, W. J., Crouse, J. R., Borrowdale, S. L., Schron, E., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043526 · Cited by 375
Self-citationChlamydia pneumoniae — an infectious risk factor for atherosclerosis?
Campbell, L. A., & Kuo, C.-C. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro796 · Cited by 277
Metadata
- Authors
- Grayston, J. T.
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2000-06
- Volume
- 181
- Issue
- s3
- Pages
- S402-S410
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2105635036
- Cited by
- 281
- References
- 1
- FWCI
- 8.33
- Type
- journal article
- Language
- en
- Open access
- closed
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- Grayston, J. T. (2000). Background and Current Knowledge of Chlamydia pneumoniae and Atherosclerosis. The Journal of Infectious Diseases. https://doi.org/10.1086/315596
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
