The DOI matches its Crossref record.
Failure of Mebendazole in the Treatment of Humans with Trichinella spiralis Infection at the Stage of Encapsulating Larvae
Abstract
Trichinella spiralis larvae infective for laboratory mice were collected from muscle biopsies performed at different times (from 1 day to 16 months) following the end of treatment, indicating the failure of mebendazole to kill Trichinella parasites when they are encapsulating in muscles.
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“However, the effect of mebendazole was limited in human trichinosis because it was effective only on newborn larvae in lymph and blood vessels but not on encapsulating larvae in muscle cells [107].”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [107]
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No references could be resolved yet.
Research works printed but not linked: 13
- Moorhead, 1999, The American Journal of Tropical Medicine and Hygiene, 60, 66, 10.4269/ajtmh.1999.60.66 · DOI
- Pozio, 1998, Parasitology today (Personal ed.), 14, 35, 10.1016/S0169-4758(97)01165-4 · DOI
- Campbell, 1964, The Journal of Parasitology, 50, 481, 10.2307/3275605 · DOI
- Campbell, 1974, Experimental parasitology, 35, 304, 10.1016/0014-4894(74)90037-X · DOI
- Lopez-Garcia, 1997, International journal for parasitology, 27, 781, 10.1016/S0020-7519(97)00052-0 · DOI
- 1998, EUROSURVEILLANCE, 3, 85, 10.2807/esm.03.08.00119-en · DOI
- Pozio, 1993, The American Journal of Tropical Medicine and Hygiene, 48, 568, 10.4269/ajtmh.1993.48.568 · DOI
- Zarlenga, 1999, International journal for parasitology, 29, 1859, 10.1016/S0020-7519(99)00107-1 · DOI
- Polvere, 1997, Experimental parasitology, 86, 191, 10.1006/expr.1997.4180 · DOI
- Pozio, 1992, The Journal of Parasitology, 78, 647, 10.2307/3283539 · DOI
- 1989, BULL SOC FRANC PARASITOL, 7, 201
- Latif, 1993, Japanese journal of medical science & biology, 46, 203, 10.7883/yoken1952.46.203 · DOI
- Fr scher, 1988, European neurology, 28, 221, 10.1159/000116271 · DOI
Cited by
Sorted by citations
Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Chai, J.-Y., Jung, B.-K., & Hong, S.-J. (2021) · The Korean Journal of Parasitology · doi:10.3347/kjp.2021.59.3.189 · Cited by 286
Metadata
- Authors
- Pozio, E., Sacchini, D., Sacchi, L., Tamburrini, A., & Alberici, F.
- Affiliations
- Istituto Superiore di Sanità (IT)
- Azienda Unità Sanitaria Locale Piacenza (IT)
- University of Pavia (IT)
- Corresponding author
- Pozio, E.
- ORCID
- Sacchi, L.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-02-15
- Volume
- 32
- Issue
- 4
- Pages
- 638-642
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2138204644
- Cited by
- 101
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 8 · 2023: 12 · 2022: 7 · 2021: 7 · 2020: 7 · 2019: 4 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 8 · 2014: 4 · 2013: 3 · 2012: 1
- FWCI
- 2.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministero della Salute
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Research on Leishmaniasis Studies
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Keywords
- Trichinella spiralis, trichinellosis, mebendazole, muscle larvae
- MeSH terms
- Animals, Antinematodal Agents, Biopsy, Humans, Larva, Mebendazole, Muscles, Trichinellosis, Trichinella spiralis, Treatment Failure
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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