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Population‐Based Incidence of Pertussis among Adolescents and Adults, Minnesota, 1995–1996

Open access
Strebel, Peter, Nordin, James, Edwards, Kathryn, Hunt, John, Besser, John, Burns, Sheila, Amundson, Gerald, Baughman, Andrew, Wattigney, Wendy·2001·The Journal of Infectious Diseases

Abstract

To estimate the incidence of pertussis, a prospective study was done among members of a managed care organization in Minneapolis/St. Paul, Minnesota. Of 212 patients 10-49 years old enrolled from January 1995 through December 1996, 8 were found to be culture positive, 10 were found to be positive by polymerase chain reaction assay, 13 had a > or =2-fold increase in IgG or IgA to pertussis toxin (PT), and 18 had IgG to PT in a single serum specimen > or =3 SD above the mean of an age-matched control group. At least 1 positive laboratory test result for pertussis infection was found in 27 (13%) patients, among whom the duration of cough illness was a median of 42 days (range, 27-66 days). On the basis of any positive laboratory result, the estimated annual incidence of pertussis was 507 cases per 100,000 person-years (95% confidence interval, 307-706 cases). Bordetella pertussis infection may be a more common cause of cough illness among adolescents and adults than was recognized previously.

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Metadata

Authors
Strebel, P., Nordin, J., Edwards, K., Hunt, J., Besser, J., Burns, S., Amundson, G., Baughman, A., & Wattigney, W.
Venue
The Journal of Infectious Diseases
Published
2001-05
Volume
183
Issue
9
Pages
1353-1359
ISSN
  • 0022-1899 (ISSN-L)
  • 1537-6613
OpenAlex
W2116317422
Cited by
223
References
0
FWCI
8.56
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Population‐Based Incidence of Pertussis among Adolescents and Adults, Minnesota, 1995–1996. https://app.cochat.ai/papers/10.1086/319853
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Strebel, P., Nordin, J., Edwards, K., Hunt, J., Besser, J., Burns, S., Amundson, G., Baughman, A., & Wattigney, W. (2001). Population‐Based Incidence of Pertussis among Adolescents and Adults, Minnesota, 1995–1996. The Journal of Infectious Diseases. https://doi.org/10.1086/319853

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.