The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Risks Factors and Prevention of Q Fever Endocarditis
Abstract
Coxiella burnetii causes acute and chronic Q fever. To evaluate the risk factors of development of chronic endocarditis following Q fever and to assess the best preventive therapy, a retrospective study of patients diagnosed as having Q fever during 1985-2000 was conducted. Twelve patients with acute Q fever who developed endocarditis and 102 patients with Q fever endocarditis were included in the study. When compared to 200 control patients with acute Q fever, preexisting valvular disease (P<10(-7)), especially a prosthetic valve (P=.01), were encountered more often among patients with endocarditis. Among patients with valvular defects, we estimate the risk of developing endocarditis to be 39%. A combination of doxycycline plus hydroxychloroquine was better at preventing the development of endocarditis than doxycycline alone (P=.009). Our results should encourage physicians to detect valvular lesions in patients with acute Q fever and to search for acute Q fever in patients with a valvulopathy and unexplained fever. A proper treatment for such patients and a scheduled follow-up should reduce the risk of developing endocarditis.
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Fournier, P. E., Casalta, J. P., Habib, G., Messana, T., & Raoult, D. (1996) · The American Journal of Medicine · doi:10.1016/s0002-9343(96)00040-x · Cited by 220
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Cited by
Natural history and pathophysiology of Q fever
Raoult, D., Marrie, T., & Mege, J. (2005) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(05)70052-9 · Cited by 767
Self-citationFournier, P., Thuny, F., Richet, H., Lepidi, H., Casalta, J., Arzouni, J., Maurin, M., Célard, M., Mainardi, J., Caus, T., et al. (2010) · Clinical Infectious Diseases · doi:10.1086/653675 · Cited by 506
Self-citationRolain, J.-M., Colson, P., & Raoult, D. (2007) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.05.015 · Cited by 401
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Metadata
- Authors
- Fenollar, F., Fournier, P., Carrieri, M. P., Habib, G., Messana, T., & Raoult, D.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-08
- Volume
- 33
- Issue
- 3
- Pages
- 312-316
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W1981174792
- Cited by
- 304
- References
- 1
- FWCI
- 4.04
- Type
- journal article
- Language
- en
- Open access
- closed
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- Fenollar, F., Fournier, P., Carrieri, M. P., Habib, G., Messana, T., & Raoult, D. (2001). Risks Factors and Prevention of Q Fever Endocarditis. Clinical Infectious Diseases. https://doi.org/10.1086/321889
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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