Cited by 65Antifungal resistance and susceptibilityReproductive tract infections researchOcular Infections and Treatments

Prevalence of Vaginal Colonization by Drug‐Resistant Candida Species in College‐Age Women with Previous Exposure to Over‐the‐Counter Azole Antifungals

Mathema, Barun, Cross, Emily, Dun, Erica, Park, Steven, Bedell, Jane, Slade, Brenda, Williams, Martha, Riley, Lee +2 more·2001·Clinical Infectious Diseases

Abstract

We enrolled 382 college-age women in a cross-sectional survey to investigate the relationship between use of over-the-counter (OTC) azole-based antifungal drugs and vaginal colonization by drug-resistant Candida. This study showed no correlation (P=.506) between previous OTC exposure and colonization of drug-resistant Candida in vaginal flora. However, a small number of resistant Candida species isolates were obtained from women with a history of multiple exposures to OTC antifungals; given the widespread use of these products, this may be an emerging concern.

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Crossref · 10.1086/322600

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References 30 · Cited by 65

Authors
Mathema, B., Cross, E., Dun, E., Park, S., Bedell, J., Slade, B., Williams, M., Riley, L., Chaturvedi, V., & Perlin, D. S.
Affiliations
  • Columbia University (US)
  • Cornell University (US)
  • University of California, Berkeley (US)
  • New York State Department of Health (US)
Venue
Clinical Infectious Diseases
Published
2001-09
Volume
33
Issue
5
Pages
e23-e27
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2073104265
Cited by
65
References
30
Citations by year
2026: 2 · 2025: 1 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 5 · 2016: 2 · 2015: 6 · 2014: 7 · 2013: 2 · 2012: 4
FWCI
1.28
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Infectious Diseases (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
  • Health Sciences › Medicine › Ophthalmology › Ocular Infections and Treatments
Keywords
vaginal colonization, azole antifungals, candidiasis, college-age women, vaginal microbiota, antifungal resistance
MeSH terms
Adult, Antifungal Agents, Azoles, Candidiasis, Vulvovaginal, Cross-Sectional Studies, Drug Resistance, Microbial, Nonprescription Drugs, Female, Humans, Middle Aged, Students, United States, Fluconazole, Prevalence

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