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Cited by 451

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Group B Streptococcal Disease in Nonpregnant Adults

Farley, Monica M.·2001·Clinical Infectious Diseases

Abstract

Group B streptococcal (GBS) disease in nonpregnant adults is increasing, particularly in elderly persons and those with significant underlying diseases. Diabetes, neurological impairment, and cirrhosis increase risk for invasive GBS disease. Skin, soft-tissue, and osteoarticular infections, pneumonia, and urosepsis are common presentations. Meningitis and endocarditis are less common but associated with serious morbidity and mortality. Disease is frequently nosocomial and may be related to the placement of an iv catheter. Recurrent infection occurs in 4.3% of survivors. Capsular serotypes Ia, III, and V account for the majority of disease in nonpregnant adults. Although group B streptococci are susceptible to penicillin, minimum inhibitory concentrations are 4-fold to 8-fold higher than for group A streptococci. Resistance to erythromycin and clindamycin is increasing. The role of antibodies in protection against GBS disease in nonpregnant adults is unresolved. However, the immunogenicity of GBS vaccines being developed for prevention of neonatal disease should be assessed for adults who are at risk.

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Metadata

Authors
Farley, M. M.
Venue
Clinical Infectious Diseases
Published
2001-08-15
Volume
33
Issue
4
Pages
556-561
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2005900554
Cited by
451
References
19
FWCI
16.61
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Group B Streptococcal Disease in Nonpregnant Adults. https://app.cochat.ai/papers/10.1086/322696
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Farley, M. M. (2001). Group B Streptococcal Disease in Nonpregnant Adults. Clinical Infectious Diseases. https://doi.org/10.1086/322696

Data sources

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.