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Cited by 179Malaria Research and ControlPhytochemical compounds biological activitiesPharmaceutical Quality and Counterfeiting

The DOI matches its Crossref record; 18 of the 19 references it cites were found in a registry or an index.

Artemisinin Antimalarials in Pregnancy: A Prospective Treatment Study of 539 Episodes of Multidrug‐Resistant Plasmodium falciparum

McGready, Rose, Cho, Thein, Keo, Napaporn Khan, Thwai, Kyaw Lay, Villegas, Leopoldo, Looareesuwan, Sornchai, White, Nicholas J., Nosten, François·2001·Clinical Infectious Diseases
DOI 10.1086/324349
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Abstract

The emergence and spread of multidrug-resistant Plasmodium falciparum compromises the treatment of malaria, especially during pregnancy, where the choice of antimalarials is already limited. Artesunate (n=528) or artemether (n=11) was used to treat 539 episodes of acute P. falciparum malaria in 461 pregnant women, including 44 first-trimester episodes. Most patients (310 [57.5%]) received re-treatments after earlier treatment with quinine or mefloquine. By use of survival analysis, the cumulative artemisinin failure rate for primary infections was 6.6% (95% confidence interval, 1.0-12.3), compared with the re-treatment failure rate of 21.7% (95% confidence interval, 15.4-28.0; P=.004). The artemisinins were well tolerated with no evidence of adverse effects. Birth outcomes did not differ significantly to community rates for abortion, stillbirth, congenital abnormality, and mean gestation at delivery. These results are reassuring, but further information about the safety of these valuable antimalarials in pregnancy is needed.

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Crossref · 10.1086/324349

Cites

18 of 18 references verified0 citation errors · 0 not checkable

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1 of the 19 references couldn’t be matched to a known paper.

Research works printed but not linked: 6

  1. Brabin B, 1993, Parassitologia, 35, 9
  2. Wickramasuriya GAW. Clinical features of malaria in pregnancy. In: Wickramasuriya GAW, ed. Malaria and ankylostomiasis in the pregnant woman. Oxford: Oxford University Press, 1937:5-90.
  3. Li GQ, 1990, Sanya Tropical Medicine Institute, 1
  4. Wang TY, 1989, J Tradit Chin Med, 9, 28
  5. 10.1080/00034989859104 · DOI
  6. 10.1016/0035-9203(91)90205-D · DOI · Paper page

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Metadata

Authors
McGready, R., Cho, T., Keo, N. K., Thwai, K. L., Villegas, L., Looareesuwan, S., White, N. J., & Nosten, F.
Affiliations
  • Mahidol University (TH)
  • Shoklo Malaria Research Unit (TH)
ORCID
Venue
Clinical Infectious Diseases
Publisher
Oxford University Press (OUP)
Published
2001-12-15
Volume
33
Issue
12
Pages
2009-2016
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
DOI
10.1086/324349
OpenAlex
W2170827091
Cited by
178
References
19
Citations by year
2026: 2 · 2023: 10 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 5 · 2017: 3 · 2016: 6 · 2015: 6 · 2014: 5 · 2013: 6 · 2012: 9
FWCI
9.64
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Infectious Diseases (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Drug Discovery › Phytochemical compounds biological activities
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pharmaceutical Quality and Counterfeiting
Keywords
artemether, artesunate, Plasmodium falciparum, multidrug resistance, malaria in pregnancy, antimalarial treatment failure, birth outcomes, drug safety in pregnancy
MeSH terms
Animals, Antimalarials, Female, Humans, Plasmodium falciparum, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Prospective Studies, Sesquiterpenes, Malaria, Falciparum, Treatment Outcome, Drug Resistance, Multiple, Artemisinins

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