The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Multiple Mechanisms of Antimicrobial Resistance in Pseudomonas aeruginosa: Our Worst Nightmare?
Abstract
Pseudomonas aeruginosa carries multiresistance plasmids less often than does Klebsiella pneumoniae, develops mutational resistance to cephalosporins less readily than Enterobacter species, and has less inherent resistance than Stenotrophomonas maltophilia. What nevertheless makes P. aeruginosa uniquely problematic is a combination of the following: the species' inherent resistance to many drug classes; its ability to acquire resistance, via mutations, to all relevant treatments; its high and increasing rates of resistance locally; and its frequent role in serious infections. A few isolates of P. aeruginosa are resistant to all reliable antibiotics, and this problem seems likely to grow with the emergence of integrins that carry gene cassettes encoding both carbapenemases and amikacin acetyltransferases.
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Cites
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Self-citationHigh Frequency of Hypermutable Pseudomonas aeruginosa in Cystic Fibrosis Lung Infection
Oliver, A., Cantón, R., Campo, P., Baquero, F., & Blázquez, J. (2000) · Science · doi:10.1126/science.288.5469.1251 · Cited by 1,465
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Masuda, N., Sakagawa, E., Ohya, S., Gotoh, N., Tsujimoto, H., & Nishino, T. (2000) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.44.12.3322-3327.2000 · Cited by 722
Lauretti, L., Riccio, M. L., Mazzariol, A., Cornaglia, G., Amicosante, G., Fontana, R., & Rossolini, G. M. (1999) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.43.7.1584 · Cited by 677
Levin, A. S., Barone, A. A., Penço, J., Santos, M. V., Marinho, I. S., Arruda, E. A. G., Manrique, E. I., & Costa, S. F. (1999) · Clinical Infectious Diseases · doi:10.1086/514732 · Cited by 612
Multidrug efflux pumps and antimicrobial resistance in Pseudomonas aeruginosa and related organisms.
Poole, K. (2001) · PubMed · Cited by 456
Of Pseudomonas, porins, pumps and carbapenems
Livermore, D. M. (2001) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/47.3.247 · Cited by 391
Self-citationJournal of Molecular Microbiology and Biotechnology
(2015) · Journal of Molecular Microbiology and Biotechnology · doi:10.1159/issn.1464-1801 · Cited by 381
Carbapenemases: a problem in waiting?
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Self-citation
Cited by
Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens
Santajit, S., & Indrawattana, N. (2016) · BioMed Research International · doi:10.1155/2016/2475067 · Cited by 1,641
Pseudomonas aeruginosa : new insights into pathogenesis and host defenses
Gellatly, S. L., & Hancock, R. E. W. (2013) · Pathogens and Disease · doi:10.1111/2049-632x.12033 · Cited by 1,295
Combination Therapy for Treatment of Infections with Gram-Negative Bacteria
Tamma, P. D., Cosgrove, S. E., & Maragakis, L. L. (2012) · Clinical Microbiology Reviews · doi:10.1128/cmr.05041-11 · Cited by 836
Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands
Cecioni, S., Imberty, A., & Vidal, S. (2015) · Chemical Reviews · doi:10.1021/cr500303t · Cited by 544
Aminoglycoside Resistance in Pseudomonas aeruginosa
Poole, K. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.2.479-487.2005 · Cited by 470
Metadata
- Authors
- Livermore, D. M.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-03-01
- Volume
- 34
- Issue
- 5
- Pages
- 634-640
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2097293600
- Cited by
- 1,453
- References
- 24
- FWCI
- 22.72
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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