The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A Novel Methicillin‐Resistance Cassette in Community‐Acquired Methicillin‐Resistant Staphylococcus aureus Isolates of Diverse Genetic Backgrounds
Open accessAbstract
Until recently, it has been unclear whether community-acquired (CA) methicillin-resistant Staphylococcus aureus (MRSA) isolates represent the spread of hospital MRSA isolates into the community. In 2 CA-MRSA isolates, a novel genetic element, designated staphylococcal cassette chromosome mec (SCCmec) type IV, was found; it differs from SCCmec types I-III in its small size and absence of non-beta-lactam genetic-resistance determinants. To study the prevalence of type IV SCCmec, polymerase chain reaction characterization of SCCmec was performed on DNA from 12 CA-MRSA isolates. The 12 CA-MRSA isolates were from diverse genetic backgrounds, as evidenced by their stratification into 5 pulsed-field gel electrophoresis types, 4 coagulase types, and 2 ribotypes. Eleven of the 12 isolates contained the novel SCCmec type IV element. Ten were resistant only to beta-lactam antibiotics. SCCmec type IV is present on the genome of CA-MRSA isolates. Its relatively small size and presence in isolates of diverse genetic backgrounds suggest that it may spread among S. aureus isolates.
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Cites
Lindenmayer, J. M., Schoenfeld, S., O'Grady, R., & Carney, J. K. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.8.895 · Cited by 298
Cited by
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David, M. Z., & Daum, R. S. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00081-09 · Cited by 1,972
Self-citationCommunity-acquired meticillin-resistant Staphylococcus aureus: an emerging threat
Zetola, N., Francis, J. S., Nuermberger, E. L., & Bishai, W. R. (2005) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(05)70112-2 · Cited by 791
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Schmidt, H., & Hensel, M. (2004) · Clinical Microbiology Reviews · doi:10.1128/cmr.17.1.14-56.2004 · Cited by 776
The molecular evolution of methicillin-resistant Staphylococcus aureus
Deurenberg, R. H., Vink, C., Kalenic, S., Friedrich, A. W., Bruggeman, C. A., & Stobberingh, E. E. (2007) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2006.01573.x · Cited by 597
Metadata
- Authors
- Daum, R. S., Ito, T., Hiramatsu, K., Hussain, F., Mongkolrattanothai, K., Jamklang, M., & Boyle‐Vavra, S.
- Venue
- The Journal of Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2002-11
- Volume
- 186
- Issue
- 9
- Pages
- 1344-1347
- ISSN
- 0022-1899 (ISSN-L)
- 1537-6613
- OpenAlex
- W2155169247
- Cited by
- 295
- References
- 1
- FWCI
- 18.95
- Type
- journal article
- Language
- en
- Open access
- bronze
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- The paper
- Daum, R. S., Ito, T., Hiramatsu, K., Hussain, F., Mongkolrattanothai, K., Jamklang, M., & Boyle‐Vavra, S. (2002). A Novel Methicillin‐Resistance Cassette in Community‐Acquired Methicillin‐Resistant Staphylococcus aureus Isolates of Diverse Genetic Backgrounds. The Journal of Infectious Diseases. https://doi.org/10.1086/344326
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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