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Cited by 361

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Oral Human Papillomavirus Infection in Adults Is Associated with Sexual Behavior and HIV Serostatus

Kreimer, Aimee R., Alberg, Anthony J., Daniel, Richard, Gravitt, Patti E., Viscidi, Rapheal, Garrett, Elizabeth S., Shah, Keerti V., Gillison, Maura L.·2004·The Journal of Infectious Diseases

Abstract

The prevalence and risk factors for oral human papillomavirus (HPV) infection are unknown, despite evidence for an etiological role for HPV in oral cancers. Oral samples from human immunodeficiency virus (HIV)-seronegative (n=396) and HIV-seropositive (n=190) adults were tested for HPV DNA. High-risk HPV infections were present in 2.1% of tonsil and 6.3% of oral-rinse specimens. The prevalence of oral high-risk HPV infection was greater in HIV-seropositive individuals (13.7% vs. 4.5%; P<.001). In multiple logistic regression, odds of oral HPV infection increased with age, male sex, and herpes simplex virus (HSV)-2 seropositivity in HIV-seronegative individuals and with CD4 cell count <200 cells/mL, HSV-2 seropositivity, oral mucosal abnormalities, and >1 oral sex partner during the previous year (odds ratio, 12.8; 95% confidence interval, 3.1-52.7) among HIV-seropositive individuals. HPV type 16, which is present in most HPV-associated tonsillar cancers, was the most prevalent high-risk oral HPV infection.

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Metadata

Authors
Kreimer, A. R., Alberg, A. J., Daniel, R., Gravitt, P. E., Viscidi, R., Garrett, E. S., Shah, K. V., & Gillison, M. L.
Venue
The Journal of Infectious Diseases
Published
2004-02-15
Volume
189
Issue
4
Pages
686-698
ISSN
  • 0022-1899 (ISSN-L)
  • 1537-6613
OpenAlex
W2129645590
Cited by
361
References
1
FWCI
9.90
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Oral Human Papillomavirus Infection in Adults Is Associated with Sexual Behavior and HIV Serostatus. https://app.cochat.ai/papers/10.1086/381504
The paper
Kreimer, A. R., Alberg, A. J., Daniel, R., Gravitt, P. E., Viscidi, R., Garrett, E. S., Shah, K. V., & Gillison, M. L. (2004). Oral Human Papillomavirus Infection in Adults Is Associated with Sexual Behavior and HIV Serostatus. The Journal of Infectious Diseases. https://doi.org/10.1086/381504

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.