The DOI matches its Crossref record.
Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the Western Australian HIV Cohort Study
Open accessAbstract
Abacavir therapy is associated with significant drug hypersensitivity in approximately 8% of recipients, with retrospective studies indicating a strong genetic association with the HLA-B*5701 allele. In this prospective study, involving 260 abacavir-naive individuals (7.7% of whom were positive for HLA-B*5701), we confirm the usefulness of genetic risk stratification, with no cases of abacavir hypersensitivity among 148 HLA-B*5701-negative recipients.
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Cited by
Saag, M., Balu, R., Phillips, E., Brachman, P., Martorell, C., Burman, W., Stancil, B., Mosteller, M., Brothers, C., Wannamaker, P., et al. (2008) · Clinical Infectious Diseases · doi:10.1086/529382 · Cited by 425
Self-citationPerceptions of genetic testing and genomic medicine among drug users
Perlman, D. C., Gelpí-Acosta, C., Friedman, S. R., Jordan, A. E., & Hagan, H. (2015) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2014.06.013 · Cited by 12
Metadata
- Authors
- Rauch, A., Nolan, D., Martin, A., McKinnon, E., Almeida, C., & Mallal, S.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-07
- Volume
- 43
- Issue
- 1
- Pages
- 99-102
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2135068975
- Cited by
- 296
- References
- 0
- FWCI
- 22.26
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the Western Australian HIV Cohort Study. https://app.cochat.ai/papers/10.1086/504874
- The paper
- Rauch, A., Nolan, D., Martin, A., McKinnon, E., Almeida, C., & Mallal, S. (2006). Prospective Genetic Screening Decreases the Incidence of Abacavir Hypersensitivity Reactions in the Western Australian HIV Cohort Study. Clinical Infectious Diseases. https://doi.org/10.1086/504874
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
