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Risk Factors for Prosthetic Joint Infection: Case‐Control Study
Open accessAbstract
We conducted a matched case-control study to determine risk factors for the development of prosthetic joint infection. Cases were patients with prosthetic hip or knee joint infection. Controls were patients who underwent total hip or knee arthroplasty and did not develop prosthetic joint infection. A multiple logistic regression model indicated that risk factors for prosthetic joint infection were the development of a surgical site infection not involving the prosthesis (odds ratio [OR], 35.9; 95% confidence interval [CI], 8.3-154.6), a National Nosocomial Infections Surveillance (NNIS) System surgical patient risk index score of 1 (OR, 1.7; 95% CI, 1.2-2.3) or 2 (OR, 3.9; 95% CI, 2.0-7.5), the presence of a malignancy (OR, 3.1; 95% CI, 1.3-7.2), and a history of joint arthroplasty (OR, 2.0; 95% CI, 1.4-3.0). Our findings suggest that a surgical site infection not involving the joint prosthesis, an NNIS System surgical patient risk index score of 1 or 2, the presence of a malignancy, and a history of a joint arthroplasty are associated with an increased risk of prosthetic joint infection.
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Citations
Cited by
Tong, S. Y. C., Davis, J. S., Eichenberger, E., Holland, T. L., & Fowler, V. G. (2015) · Clinical Microbiology Reviews · doi:10.1128/cmr.00134-14 · Cited by 5,192
Candida Infections of Medical Devices
Kojic, E. M., & Darouiche, R. O. (2004) · Clinical Microbiology Reviews · doi:10.1128/cmr.17.2.255-267.2004 · Cited by 1,055
Synovial fluid leukocyte count and differential for the diagnosis of prosthetic knee infection
Trampuz, A., Hanssen, A. D., Osmon, D. R., Mandrekar, J., Steckelberg, J. M., & Patel, R. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2004.06.022 · Cited by 555
Self-citationBackgrounds of antibiotic-loaded bone cement and prosthesis-related infection
Hendriks, J. G. E., van Horn, J. R., van der Mei, H. C., & Busscher, H. J. (2004) · Biomaterials · doi:10.1016/s0142-9612(03)00554-4 · Cited by 291
Zhu, Y., Zhang, F., Chen, W., Liu, S., Zhang, Q., & Zhang, Y. (2015) · Journal of Hospital Infection · doi:10.1016/j.jhin.2014.10.008 · Cited by 217
Metadata
- Authors
- Berbari, E. F., Hanssen, A. D., Duffy, M. C., Steckelberg, J. M., Ilstrup, D. M., Harmsen, W. S., & Osmon, D. R.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 1998-11
- Volume
- 27
- Issue
- 5
- Pages
- 1247-1254
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2111293729
- Cited by
- 840
- References
- 0
- FWCI
- 6.66
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Berbari, E. F., Hanssen, A. D., Duffy, M. C., Steckelberg, J. M., Ilstrup, D. M., Harmsen, W. S., & Osmon, D. R. (1998). Risk Factors for Prosthetic Joint Infection: Case‐Control Study. Clinical Infectious Diseases. https://doi.org/10.1086/514991
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