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Cited by 2,442

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The Global Burden of Nontyphoidal Salmonella Gastroenteritis

Majowicz, Shannon E., Musto, Jennie, Scallan, Elaine, Angulo, Frederick J., Kirk, Martyn, O’Brien, Sarah J., Jones, Timothy F., Fazil, Aamir, Hoekstra, Robert M.·2010·Clinical Infectious Diseases

Abstract

To estimate the global burden of nontyphoidal Salmonella gastroenteritis, we synthesized existing data from laboratory-based surveillance and special studies, with a hierarchical preference to (1) prospective population-based studies, (2) "multiplier studies," (3) disease notifications, (4) returning traveler data, and (5) extrapolation. We applied incidence estimates to population projections for the 21 Global Burden of Disease regions to calculate regional numbers of cases, which were summed to provide a global number of cases. Uncertainty calculations were performed using Monte Carlo simulation. We estimated that 93.8 million cases (5th to 95th percentile, 61.8-131.6 million) of gastroenteritis due to Salmonella species occur globally each year, with 155,000 deaths (5th to 95th percentile, 39,000-303,000 deaths). Of these, we estimated 80.3 million cases were foodborne. Salmonella infection represents a considerable burden in both developing and developed countries. Efforts to reduce transmission of salmonellae by food and other routes must be implemented on a global scale.

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Metadata

Authors
Majowicz, S. E., Musto, J., Scallan, E., Angulo, F. J., Kirk, M., O’Brien, S. J., Jones, T. F., Fazil, A., & Hoekstra, R. M.
Venue
Clinical Infectious Diseases
Published
2010-03-15
Volume
50
Issue
6
Pages
882-889
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2101997581
Cited by
2,442
References
2
FWCI
96.98
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Global Burden of Nontyphoidal Salmonella Gastroenteritis. https://app.cochat.ai/papers/10.1086/650733
The paper
Majowicz, S. E., Musto, J., Scallan, E., Angulo, F. J., Kirk, M., O’Brien, S. J., Jones, T. F., Fazil, A., & Hoekstra, R. M. (2010). The Global Burden of Nontyphoidal Salmonella Gastroenteritis. Clinical Infectious Diseases. https://doi.org/10.1086/650733

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.