The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Statement on Pregnancy in Pulmonary Hypertension from the Pulmonary Vascular Research Institute
Open accessAbstract
Pregnancy outcomes in patients with pulmonary hypertension remain poor despite advanced therapies. Although consensus guidelines recommend against pregnancy in pulmonary hypertension, it may nonetheless occasionally occur. This guideline document sought to discuss the state of knowledge of pregnancy effects on pulmonary vascular disease and to define usual practice in avoidance of pregnancy and pregnancy management. This guideline is based on systematic review of peer‐reviewed, published literature identified with MEDLINE. The strength of the literature was graded, and when it was inadequate to support high‐level recommendations, consensus‐based recommendations were formed according to prespecified criteria. There was no literature that met standards for high‐level recommendations for pregnancy management in pulmonary hypertension. We drafted 38 consensus‐based recommendations on pregnancy avoidance and management. Further, we identified the current state of knowledge on the effects of sex hormones during pregnancy on the pulmonary vasculature and right heart and suggested areas for future study. There is currently limited evidence‐based knowledge about both the basic molecular effects of sex hormones and pregnancy on the pulmonary vasculature and the best practices in contraception and pregnancy management in pulmonary hypertension. We have drafted 38 consensus‐based recommendations to guide clinicians in these challenging topics, but further research is needed in this area to define best practices and improve patient outcomes.
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Cites
Updated clinical classification of pulmonary hypertension
Simonneau, G., Gatzoulis, M. A., Adatia, I., Celermajer, D., Denton, C., Ghofrani, A., Gomez Sanchez, M. A., Krishna Kumar, R., Landzberg, M., Machado, R. F., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.10.029 · Cited by 4,191
Benza, R. L., Miller, D. P., Gomberg-Maitland, M., Frantz, R. P., Foreman, A. J., Coffey, C. S., Frost, A., Barst, R. J., Badesch, D. B., Elliott, C. G., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.898122 · Cited by 1,547
Hemostasis during normal pregnancy and puerperium
Hellgren, M. (2003) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-2003-38897 · Cited by 492
Incidence of arrhythmias in normal pregnancy and relation to palpitations, dizziness, and syncope
Shotan, A., Ostrzega, E., Mehra, A., Johnson, J. V., & Elkayam, U. (1997) · The American Journal of Cardiology · doi:10.1016/s0002-9149(97)00047-7 · Cited by 267 · cited 1×
“These shifts in cardiac axis and anatomy, in combination with hemodynamic, hormonal, and autonomic changes, represent the major causes of the frequently observed benign supraventricular arrhythmias during pregnancy.(47) Similarly, increases in heart rate by 15–20 beats per minute are common.”
BackgroundCleland, K., Zhu, H., Goldstuck, N., Cheng, L., & Trussell, J. (2012) · Human Reproduction · doi:10.1093/humrep/des140 · Cited by 265
Mantha, S., Karp, R., Raghavan, V., Terrin, N., Bauer, K. A., & Zwicker, J. I. (2012) · BMJ · doi:10.1136/bmj.e4944 · Cited by 258
Isoherranen, N., & Thummel, K. E. (2013) · Drug Metabolism and Disposition · doi:10.1124/dmd.112.050245 · Cited by 239
Cited by
2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy
Regitz-Zagrosek, V., Roos-Hesselink, J. W., Bauersachs, J., Blomström-Lundqvist, C., Cífková, R., De Bonis, M., Iung, B., Johnson, M. R., Kintscher, U., Kranke, P., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy340 · Cited by 2,292
Metadata
- Authors
- Hemnes, A. R., Kiely, D. G., Cockrill, B. A., Safdar, Z., Wilson, V. J., Hazmi, M. A., Preston, I. R., MacLean, M. R., & Lahm, T.
- Venue
- Pulmonary Circulation
- Publisher
- Wiley
- Published
- 2015-09
- Volume
- 5
- Issue
- 3
- Pages
- 435-465
- ISSN
- 2045-8932 (ISSN-L)
- 2045-8940
- OpenAlex
- W2310788539
- Cited by
- 334
- References
- 7
- FWCI
- 22.98
- Type
- journal article
- Language
- en
- Open access
- bronze
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