The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Magnetic resonance imaging of radiation dose distributions using a polymer-gel dosimeter
Open accessAbstract
A new formulation of a tissue-equivalent polymer-gel dosimeter for the measurement of three-dimensional dose distributions of ionizing radiation has been developed. It is composed of aqueous gelatin infused with acrylamide and N, N'-methylene-bisacrylamide monomers, and made hypoxic by nitrogen saturation. Irradiation of the gel, referred to as BANG, causes localized polymerization of the monomers, which, in turn, reduces the transverse NMR relaxation times of water protons. The dose dependence of the NMR transverse relaxation rate, R2, is reproducible (less than 2% variation) and is linear up to about 8 Gy, with a slope of 0.25 s(-1)Gy(-1) at 1.5 T. Magnetic resonance imaging may be used to obtain accurate three-dimensional dose distributions with high spatial resolution. Since the radiation-induced polymers do not diffuse through the gelatin matrix, the dose distributions recorded by BANG gels are stable for long periods of time, and may be used to measure low-activity radioactive sources. Since the light-scattering properties of the polymerized regions are different from those of the clear, non-irradiated regions, the dose distributions are visible, and their optical densities are dependent on dose.
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Citations
Cites
An Algorithm for Least-Squares Estimation of Nonlinear Parameters
Marquardt, D. W. (1963) · Journal of the Society for Industrial and Applied Mathematics · doi:10.1137/0111030 · Cited by 30,728
Introduction to radiation chemistry
(1991) · Environment International · doi:10.1016/0160-4120(91)90298-5 · Cited by 1,735
Measurement of radiation dose distributions by nuclear magnetic resonance (NMR) imaging
Gore, J. C., & Kang, Y. S. (1984) · Physics in Medicine and Biology · doi:10.1088/0031-9155/29/10/002 · Cited by 518
Self-citationFactors Affecting the Oxygen Tension around Cells Growing in Plastic Petri Dishes
Chapman, J. D., Sturrock, J. E., Boag, J. W., & Crookall, J. O. (1970) · International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine · doi:10.1080/09553007014550381 · Cited by 93
Zhong, J., Gore, J. C., & Armitage, I. M. (1989) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910110304 · Cited by 79
Self-citationRadiation induced polymerization
CHAPIRO, A. (1979) · Radiation Physics and Chemistry (1977) · doi:10.1016/0146-5724(79)90015-3 · Cited by 62
Metadata
- Authors
- Maryanski, M. J., Schulz, R. J., Ibbott, G. S., Gatenby, J. C., Xie, J., Horton, D., & Gore, J. C.
- Venue
- Physics in Medicine and Biology
- Publisher
- IOP Publishing
- Published
- 1994-09-01
- Volume
- 39
- Issue
- 9
- Pages
- 1437-1455
- ISSN
- 0031-9155 (ISSN-L)
- 1361-6560
- OpenAlex
- W1998828795
- Cited by
- 451
- References
- 6
- FWCI
- 8.50
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Maryanski, M. J., Schulz, R. J., Ibbott, G. S., Gatenby, J. C., Xie, J., Horton, D., & Gore, J. C. (1994). Magnetic resonance imaging of radiation dose distributions using a polymer-gel dosimeter. Physics in Medicine and Biology. https://doi.org/10.1088/0031-9155/39/9/010
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