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The DOI matches its OpenAlex record; 45 of the 45 references it cites were found in a registry or an index.

A review of methods for spike sorting: the detection and classification of neural action potentials

Michael S. Lewicki·1998·Network Computation in Neural Systems

Abstract

The detection of neural spike activity is a technical challenge that is a prerequisite for studying many types of brain function. Measuring the activity of individual neurons accurately can be difficult due to large amounts of background noise and the difficulty in distinguishing the action potentials of one neuron from those of others in the local area. This article reviews algorithms and methods for detecting and classifying action potentials, a problem commonly referred to as spike sorting. The article first discusses the challenges of measuring neural activity and the basic issues of signal detection and classification. It reviews and illustrates algorithms and techniques that have been applied to many of the problems in spike sorting and discusses the advantages and limitations of each and the applicability of these methods for different types of experimental demands. The article is written both for the physiologist wanting to use simple methods that will improve experimental yield and minimize the selection biases of traditional techniques and for those who want to apply or extend more sophisticated algorithms to meet new experimental challenges.

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Citations

Cites

Show all 45 references

Research works printed but not linked: 14

  1. Sahani, M and Pezaris, J and Andersen, R. (1997) Extracellular recording from adjacent neurons. I: a maximum-likelihood solution to the spike separation problem Soc. Neurosci. Abstr., 23, pp. 1546.
  2. Simon, W. (1965) The real-time sorting of neuro-electric action potentials in multiple unit studies Electroenceph. Clin. Neurophysiol., 18, pp. 192 - 5. · doi:10.1016/0013-4694(65)90029-5
  3. Stein, R and Andreassen, S and Oguztoreli, M. (1979) Mathematical analysis of optimal multichannel filtering for nerve signals Biol. Cybern., 32, pp. 19 - 24. · doi:10.1007/bf00337447
  4. Zhang, K-C and Sejnowski, T and McNaughton, B. (1997) Automatic separation of spike parameter clusters from tetrode recordings Soc. Neurosci. Abstr., 23, pp. 504.
  5. Millecchia, R and McIntyre, R. (1978) Automatic nerve impulse identification and separation Comput. Biomed. Res., 11, pp. 459 - 68. · doi:10.1016/0010-4809(78)90003-4
  6. Prochazka, V and Conrad, B and Sindermann, F. (1972) A neuroelectric signal recognition system Electroenceph. Clin. Neurophysiol., 32, pp. 95 - 7. · doi:10.1016/0013-4694(72)90234-9
  7. Recce, M and O'Keefe, J. (1989) The tetrode: a new technique for multi-unit extracellular recording Soc. Neurosci. Abstr., 15, pp. 1250.
  8. Brown, G and Yamada, S and Luebben, H and Sejnowski, T. (1998) Spike sorting and artifact rejection by independent component analysis of optical recordings from tritonia Soc. Neurosci. Abstr., 24, pp. 1670. no 655.3
  9. Capowski, J.(1976) The spike program: a computer system for analysis of neurophysiological action potentials. In Computer Technology in Neuroscience. ( pp. 237 - 51 ). Washington DC: Hemisphere.
  10. D'Hollander, E and Orban, G. (1979) Spike recognition and on-line classification by an unsupervised learning system IEEE Trans. Biomed. Eng., 26, pp. 279 - 84. · doi:10.1109/tbme.1979.326403
  11. Dinning, G. (1981) Real-time classification of multiunit neural signals using reduced feature sets IEEE Trans. Biomed. Eng., 28, pp. 804 - 12. · doi:10.1109/tbme.1981.324679
  12. Feldman, J and Roberge, F. (1971) Computer detection and analysis of neuronal spike sequences Inform., 9, pp. 185 - 97.
  13. Gozani, S and Miller, J. (1994) Optimal discrimination and classification of neuronal action-potential wave-forms from multiunit, multichannel recordings using software-based linear filters IEEE Trans. Biomed. Eng., 41, pp. 358 - 72. · doi:10.1109/10.284964
  14. Keehn, D. (1966) An iterative spike separation technique IEEE Trans. Biomed. Eng., 13, pp. 19 - 28. · doi:10.1109/tbme.1966.4502395

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Metadata

Authors
Lewicki, M. S.
Venue
Network Computation in Neural Systems
Published
1998-11-01
Volume
9
Issue
4
Pages
R53-R78
ISSN
  • 0954-898X (ISSN-L)
  • 1361-6536
OpenAlex
W2171406132
Cited by
1,370
References
45
FWCI
2.35
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A review of methods for spike sorting: the detection and classification of neural action potentials. https://app.cochat.ai/papers/10.1088/0954-898x/9/4/001
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Lewicki, M. S. (1998). A review of methods for spike sorting: the detection and classification of neural action potentials. Network Computation in Neural Systems. https://doi.org/10.1088/0954-898x/9/4/001

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