The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Dying Trajectory in the Last Year of Life: Does Cancer Trajectory Fit Other Diseases?
Abstract
PURPOSE: To examine differences in the pattern of functional decline among persons dying of cancer and other leading noncancer causes of death. DESIGN: Mortality followback survey of next of kin listed on death certificate. SETTING: Probability sample of all deaths in the United States. PARTICIPANTS: Next of kin for 3,614 decedents that represented 914,335 deaths. MEASUREMENTS: Days of difficulty with activities of daily living and mobility in the last year of life. RESULTS: Relative to other decedents, patients with cancer experienced an increased rate of functional impairment beginning as late as 5 months prior to death. For example, only 13.9% of patients with cancer had difficulty getting out of bed or a chair 1-year prior to death. This increased from 22.2% to 63.0% in the last five months of life. In contrast, decedents from other diseases had higher rates of functional impairment 1 year prior to death (approximately 35% had difficulty getting out of bed or chair) and they manifested a more gradual increase in the level of functional decline (approximately 50% had difficulty getting out of bed). Precipitous functional decline was associated with hospice involvement and dying at home. CONCLUSION: Persons dying of cancer experienced sharp functional decline in the last months of life whereas other decedents' have a more gradual decline. The more precipitous functional decline was associated with hospice involvement and dying at home.
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“When controlling for potential covariates, subjective sleep quality (assessed by the PSQI) and insomnia status were predictive of the influenza antibody response”
From The Sleep-Immune Crosstalk in Health and Disease (2019) · cites this paper as [536]
In the citing paper
“the vaccination response to influenza did not differ between 133 healthy college students with or without insomnia (based on DSM-V criteria), although the insomnia group had overall lower antibody amounts pre- and post-vaccination”
From The Sleep-Immune Crosstalk in Health and Disease (2019) · cites this paper as [536]
In the citing paper
“Such abnormalities reported for basal immune and inflammatory markers in insomnia disorder may underlie inadequate influenza vaccine responses as recently reported”
From The Sleep-Immune Crosstalk in Health and Disease (2019) · cites this paper as [536]
In the citing paper
“which led the authors to suggest that both may attenuate immunity to the influenza virus”
From The Sleep-Immune Crosstalk in Health and Disease (2019) · cites this paper as [536]
Citations
Cites
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Longer Life but Worsening Health? Trends in Health and Mortality of Middle-Aged and Older Persons
Verbrugge, L. M. (1984) · The Milbank Memorial Fund Quarterly Health and Society · doi:10.2307/3349861 · Cited by 522
American Medical Association Council on Scientific Affairs
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Will to live in the terminally ill
Chochinov, H. M. (1999) · The Lancet · doi:10.1016/s0140-6736(98)11448-4 · Cited by 243
Last days: A study of the quality of life of terminally ill cancer patients
Morris, J. N., Suissa, S., Sherwood, S., Wright, S. M., & Greer, D. S. (1986) · Journal of Chronic Diseases · doi:10.1016/0021-9681(86)90106-2 · Cited by 226
Good Care of the Dying Patient
Davis, R. M. (1996) · JAMA · doi:10.1001/jama.1996.03530300058041 · Cited by 223
Are bereaved family members a valid proxy for a patient's assessment of dying?
Higginson, I. J., Priest, P. C., & McCarthy, M. I. (1994) · Social Science & Medicine · doi:10.1016/0277-9536(94)90251-8 · Cited by 197
Preferences for cardiopulmonary resuscitation
the SUPPORT Investigators, Teno, J. M., Hakim, R. B., Knaus, W. A., Wenger, N. S., Phillips, R. S., Wu, A. W., Layde, P. M., Connors, A. F., Dawson, N. V., et al. (1995) · Journal of General Internal Medicine · doi:10.1007/bf02600252 · Cited by 135
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The Sleep-Immune Crosstalk in Health and Disease
Besedovsky, L., Lange, T., & Haack, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00010.2018 · Cited by 1,479
Patterns of Functional Decline at the End of Life
Lunney, J. R. (2003) · JAMA · doi:10.1001/jama.289.18.2387 · Cited by 1,418
Factors influencing death at home in terminally ill patients with cancer: systematic review
Gomes, B., & Higginson, I. J. (2006) · BMJ · doi:10.1136/bmj.38740.614954.55 · Cited by 976
End-of-Life Care Preferences and Needs
Davison, S. N. (2010) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.05960809 · Cited by 630
Evidence for Improving Palliative Care at the End of Life: A Systematic Review
Lorenz, K., Lynn, J., Dy, S. M., Shugarman, L. R., Wilkinson, A., Mularski, R. A., Morton, S. C., Hughes, R. G., Hilton, L. K., Maglione, M., et al. (2008) · Annals of Internal Medicine · doi:10.7326/0003-4819-148-2-200801150-00010 · Cited by 590
Metadata
- Authors
- Teno, J. M., Weitzen, S., Fennell, M. L., & Mor, V.
- Affiliations
- Brown University (US)
- Venue
- Journal of Palliative Medicine
- Publisher
- SAGE Publications
- Published
- 2001-12
- Volume
- 4
- Issue
- 4
- Pages
- 457-464
- ISSN
- 1096-6218 (ISSN-L)
- 1557-7740
- OpenAlex
- W2046867396
- Cited by
- 290
- References
- 22
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 5 · 2023: 11 · 2022: 9 · 2021: 11 · 2020: 7 · 2019: 18 · 2018: 14 · 2017: 14 · 2016: 16 · 2015: 10 · 2014: 12 · 2013: 10 · 2012: 18
- FWCI
- 8.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Palliative Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Robert Wood Johnson Foundation
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- functional decline, last year of life, cancer mortality, activities of daily living, mobility impairment, hospice care, home death, next of kin
- MeSH terms
- Activities of Daily Living, Data Collection, Death, Death Certificates, Diabetes Mellitus, Heart Failure, Humans, Neoplasms, Prognosis, United States, Hospice Care, Disease Progression, Stroke, Pulmonary Disease, Chronic Obstructive
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