The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
MINMOD Millennium: A Computer Program to Calculate Glucose Effectiveness and Insulin Sensitivity from the Frequently Sampled Intravenous Glucose Tolerance Test
Abstract
The Bergman Minimal Model enables estimation of two key indices of glucose/insulin dynamics: glucose effectiveness and insulin sensitivity. In this paper we describe MINMOD Millennium, the latest Windows-based version of minimal model software. Extensive beta testing of MINMOD Millennium has shown that it is user-friendly, fully automatic, fast, accurate, reproducible, repeatable, and highly concordant with past versions of MINMOD. It has a simple interface, a comprehensive help system, an input file editor, a file converter, an intelligent processing kernel, and a file exporter. It provides publication-quality charts of glucose and insulin and a table of all minimal model parameters and their error estimates. In contrast to earlier versions of MINMOD and some other minimal model programs, Millennium provides identified estimates of insulin sensitivity and glucose effectiveness for almost every subject.
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Cites
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Global and societal implications of the diabetes epidemic
Zimmet, P., Alberti, K. G. M. M., & Shaw, J. (2001) · Nature · doi:10.1038/414782a · Cited by 5,883
Quantitative estimation of insulin sensitivity.
Bergman, R. N., Ider, Y. Z., Bowden, C. R., & Cobelli, C. (1979) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1979.236.6.e667 · Cited by 1,874
Self-citationBuchanan, T. A., Xiang, A. H., Peters, R. K., Kjos, S. L., Marroquin, A., Goico, J., Ochoa, C., Tan, S., Berkowitz, K., Hodis, H. N., et al. (2002) · Diabetes · doi:10.2337/diabetes.51.9.2796 · Cited by 1,339
Rudic, R. D., McNamara, P., Curtis, A.-M., Boston, R. C., Panda, S., Hogenesch, J. B., & FitzGerald, G. A. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020377 · Cited by 1,059
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Rudic, R. D., McNamara, P., Curtis, A.-M., Boston, R. C., Panda, S., Hogenesch, J. B., & FitzGerald, G. A. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020377 · Cited by 1,059
Self-citationSunny, N. E., Parks, E. J., Browning, J. D., & Burgess, S. C. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.11.004 · Cited by 672
Leproult, R., Holmbäck, U., & Van Cauter, E. (2014) · Diabetes · doi:10.2337/db13-1546 · Cited by 607
“Minimal model analyses (21) were performed using the Minmod Millennium software (22) and provided SI, the acute insulin response to glucose (AIRg), a measure of b-cell response, and the disposition index (DI = AIRg 3 SI), a marker of diabetes risk.”
MethodLarson-Meyer, D. E., Heilbronn, L. K., Redman, L. M., Newcomer, B. R., Frisard, M. I., Anton, S., Smith, S. R., Alfonso, A., Ravussin, E., & the Pennington CALERIE Team (2006) · Diabetes Care · doi:10.2337/dc05-2565 · Cited by 504
Spencer, M., Yao-Borengasser, A., Unal, R., Rasouli, N., Gurley, C. M., Zhu, B., Peterson, C. A., & Kern, P. A. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00329.2010 · Cited by 439
Metadata
- Authors
- Boston, R. C., Stefanovski, D., Moate, P. J., Sumner, A. E., Watanabe, R. M., & Bergman, R. N.
- Venue
- Diabetes Technology & Therapeutics
- Publisher
- SAGE Publications
- Published
- 2003-12
- Volume
- 5
- Issue
- 6
- Pages
- 1003-1015
- ISSN
- 1520-9156 (ISSN-L)
- 1557-8593
- OpenAlex
- W2176172321
- Cited by
- 431
- References
- 6
- FWCI
- 7.74
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: MINMOD Millennium: A Computer Program to Calculate Glucose Effectiveness and Insulin Sensitivity from the Frequently Sampled Intravenous Glucose Tolerance Test. https://app.cochat.ai/papers/10.1089/152091503322641060
- The paper
- Boston, R. C., Stefanovski, D., Moate, P. J., Sumner, A. E., Watanabe, R. M., & Bergman, R. N. (2003). MINMOD Millennium: A Computer Program to Calculate Glucose Effectiveness and Insulin Sensitivity from the Frequently Sampled Intravenous Glucose Tolerance Test. Diabetes Technology & Therapeutics. https://doi.org/10.1089/152091503322641060
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