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Cited by 334

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

The Complete Nucleotide Sequence of a Pathogenic Molecular Clone of Simian Immunodeficiency Virus

REGIER, DEAN A., DESROSIERS, RONALD C.·1990·AIDS Research and Human Retroviruses

Abstract

The complete nucleotide sequence of an infectious clone of simian immunodeficiency virus of macaques, SIVmac239, has been determined. Virus produced from this molecular clone causes AIDS in rhesus monkeys in a time frame suitable for laboratory investigation. The proviral genome including both long terminal repeats is 10,279 base pairs in length and contains open reading frames for gag, pol, vif, vpr, vpx, tat, rev, and env. The nef gene contains an in-frame premature stop after the 92nd codon. At the nucleotide level, SIVmac239 is closely related to SIVmac251 (98%) and SIVmac142 (96%). It will not be possible to test which features of the viral sequence are critical molecular determinants for the pathogenesis of AIDS.

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Crossref · 10.1089/aid.1990.6.1221

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Metadata

Authors
REGIER, D. A., & DESROSIERS, R. C.
Venue
AIDS Research and Human Retroviruses
Published
1990-11
Volume
6
Issue
11
Pages
1221-1231
ISSN
  • 0889-2229 (ISSN-L)
  • 1931-8405
OpenAlex
W1576742764
Cited by
334
References
2
FWCI
4.30
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Complete Nucleotide Sequence of a Pathogenic Molecular Clone of Simian Immunodeficiency Virus. https://app.cochat.ai/papers/10.1089/aid.1990.6.1221
The paper
REGIER, D. A., & DESROSIERS, R. C. (1990). The Complete Nucleotide Sequence of a Pathogenic Molecular Clone of Simian Immunodeficiency Virus. AIDS Research and Human Retroviruses. https://doi.org/10.1089/aid.1990.6.1221

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.