Genetic Modification of the Lung Directed Toward Treatment of Human Disease

Cites (609)

Items 201–400 of 609

1. Current Strategies and Future Directions for Eluding Adenoviral Vector Immunity
   Dinesh S. Bangari, Suresh K. Mittal · 2006 · Current Gene Therapy
2. The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery
   Anson, Donald S · 2004 · Genetic Vaccines and Therapy
3. Phase III Study of Gemcitabine and Cisplatin With or Without Aprinocarsen, a Protein Kinase C-Alpha Antisense Oligonucleotide, in Patients With Advanced-Stage Non–Small-Cell Lung Cancer
   Luis G Paz-Ares, Jean‐Yves Douillard, P. Koralewski, Christian Manegold, Egbert Frederik Smit, José Miguel Reyes, Gee‐Chen Chang, William J. John, Patrick M. Peterson, Coleman K. Obasaju et al. · 2006 · Journal of Clinical Oncology
4. Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors
   Sihong Song, Jennifer E. Embury, PJ Laipis, KI Berns, JM Crawford, Terence R. Flotte · 2001 · Gene Therapy
5. Adeno-associated virus–targeted disruption of the CFTR gene in cloned ferrets
   Xingshen Sun, Ziying Yan, Yaling Yi, Ziyi Li, Diana Lei, Christopher S. Rogers, Juan Chen, Yulong Zhang, Michael J. Welsh, Gregory H. Leno et al. · 2008 · Journal of Clinical Investigation
6. Inhibition of invasion, angiogenesis, tumor growth, and metastasis by adenovirus-mediated transfer of antisense uPAR and MMP-9 in non–small cell lung cancer cells
   Jasti Sambasiva Rao, Christopher S. Gondi, Chandramu Chetty, Subramanyam Chittivelu, Pushpa A. Joseph, Sajani S. Lakka · 2005 · Molecular Cancer Therapeutics
7. Pneumonic Plague: The Darker Side of Yersinia pestis
   Roger D. Pechous, Vijay Sivaraman, Nikolas M. Stasulli, William E. Goldman · 2015 · Trends in Microbiology
8. Phase II trial of Belagenpumatucel-L, a TGF-β2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients
   Nemunaitis, J, Nemunaitis, M, Senzer, N, Snitz, P, Bedell, C, Kumar, P, Pappen, B, Maples, P B, Shawler, D, Fakhrai, H · 2009 · Cancer Gene Therapy
9. Development of Sendai virus vectors and their potential applications in gene therapy and regenerative medicine
   Nakanishi, Mahito, Otsu, Makoto · 2012 · Current Gene Therapy
10. Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension
    Ann M. Reynolds, Wei Xia, Mark Holmes, Sandra J. Hodge, Sergei M. Danilov, David T. Curiel, Nicholas W. Morrell, Paul N. Reynolds · 2007 · American Journal of Physiology-Lung Cellular and Molecular Physiology
11. Intranasal Gene Transfer by Chitosan–DNA Nanospheres Protects BALB/c Mice Against Acute Respiratory Syncytial Virus Infection
    Mukesh Kumar, Aruna K. Behera, Richard F. Lockey, Jian Zhang, Guraman Bhullar, Cristina Perez de la Cruz, Li‐Chen Chen, Kam W. Leong, Shau-Ku Huang, Shyam S. Mohapatra · 2002 · Human Gene Therapy
12. Baculovirus Vectors for Gene Therapy
    Yu‐Chen Hu · 2006 · Advances in virus research
13. RNA Interference-Mediated Silencing of the Respiratory Syncytial Virus Nucleocapsid Defines a Potent Antiviral Strategy
    Rene Alvarez, Sayda M. Elbashir, Todd D. Borland, Ivanka Toudjarska, Philipp Hadwiger, Mathias John, Ingo Roehl, Svetlana Shulga‐Morskaya, Rick Martinello, Jeffrey S. Kahn et al. · 2009 · Antimicrobial Agents and Chemotherapy
14. Increasing Epithelial Junction Permeability Enhances Gene Transfer to Airway Epithelia In Vivo
    Guoshun Wang, Joseph Zabner, Camille Deering, Jan L. Launspach, Jianqiang Shao, Mordechai Bodner, Doug J. Jolly, Beverly L. Davidson, Paul B. McCray · 2000 · American Journal of Respiratory Cell and Molecular Biology
15. Acute Responses of Non-Human Primates to Airway Delivery of an Adenovirus Vector Containing the Human Cystic Fibrosis Transmembrane Conductance Regulator cDNA
    Steven L. Brody, Mark E. Metzger, Claire J. Danel, Melissa A. Rosenfeld, Ronald G. Crystal · 1994 · Human Gene Therapy
16. Long-term Follow-up of Patients with Malignant Pleural Mesothelioma Receiving High-Dose Adenovirus Herpes Simplex Thymidine Kinase/Ganciclovir Suicide Gene Therapy
    Daniel H. Sterman, Adriana Recio, Anil Vachani, Jing Sun, Lumei Cheung, Peter A. DeLong, Kunjlata M. Amin, Leslie A. Litzky, James M. Wilson, Larry R. Kaiser et al. · 2005 · Clinical Cancer Research
17. Adenovirus-mediated transfer of heme oxygenase-1 cDNA attenuates severe lung injury induced by the influenza virus in mice
    Tomonori Hashiba, Motoyoshi Suzuki, Yoji Nagashima, Shunsuke Suzuki, S Inoue, Takahiro Tsuburai, Takeshi Matsuse, Y Ishigatubo · 2001 · Gene Therapy
18. In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency
    Mahiny, Azita J, Dewerth, Alexander, Mays, Lauren E, Alkhaled, Mohammed, Mothes, Benedikt, Malaeksefat, Emad, Loretz, Brigitta, Rottenberger, Jennifer, Brosch, Darina M, Reautschnig, Philipp et al. · 2015 · Nature Biotechnology
19. Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium
    Nicole Ali McNeer, Kavitha K. Anandalingam, Rachel J. Fields, Christina R. Caputo, Sascha Kopic, Anisha Gupta, Elias Quijano, Lee A. Polikoff, Yong Kong, Raman Bahal et al. · 2015 · Nature Communications
20. Retroviral integration and human gene therapy
    Bushman, Frederic D. · 2007 · Journal of Clinical Investigation
21. Gene therapy for lung cancer: Enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer
    Dao M. Nguyen, Francis R. Spitz, Nancy Yen, Richard J. Cristiano, Jack A. Roth · 1996 · Journal of Thoracic and Cardiovascular Surgery
22. Recovery of Airway Cystic Fibrosis Transmembrane Conductance Regulator Function in Mice with Cystic Fibrosis After Single-Dose Lentivirus-Mediated Gene Transfer
    Maria P. Limberis, Donald S. Anson, Maria Fuller, David Parsons · 2002 · Human Gene Therapy
23. Toward Gene Therapy for Cystic Fibrosis Using a Lentivirus Pseudotyped With Sendai Virus Envelopes
    Katsuyuki Mitomo, Uta Griesenbach D, Makoto Inoue, Lucinda Somerton, Cuixiang Meng, Eiji Akiba, Toshiaki Tabata, Yasuji Ueda, Gad M Frankel, Raymond Farley et al. · 2010 · Molecular Therapy
24. Role of Alveolar Macrophages in Rapid Elimination of Adenovirus Vectors Administered to the Epithelial Surface of the Respiratory Tract
    Stefan Worgall, Philip L. Leopold, G. Wolff, Barbara Ferris, Nico van Roijen, Ronald G. Crystal · 1997 · Human Gene Therapy
25. Lung disease in the cystic fibrosis mouse exposed to bacterial pathogens
    Donald J. Davidson, Julia R. Dorin, Gerry McLachlan, Vincent Ranaldi, D Lamb, Catherine J. Doherty, John R. W. Govan, David John Porteous · 1995 · Nature Genetics
26. Clonal Gene Therapy: Transplanted Mouse Fibroblast Clones Express Human α1-Antitrypsin Gene in Vivo
    Robert I. Garver, Anna M. Chytil, Michael Courtney, Ronald G. Crystal · 1987 · Science
27. Modification of Nasal Epithelial Potential Differences of Individuals with Cystic Fibrosis Consequent to Local Administration of a Normal CFTR cDNA Adenovirus Gene Transfer Vector
    John G. Hay, Noel Gerard McElvaney, Juan Herena, Ronald G. Crystal · 1995 · Human Gene Therapy
28. A Phase I Trial of Repeated Intrapleural Adenoviral-mediated Interferon-β Gene Transfer for Mesothelioma and Metastatic Pleural Effusions
    Daniel H. Sterman, Adri Recio, Andrew R. Haas, Anil Vachani, Sharyn I. Katz, Colin T. Gillespie, Guanjun Cheng, Jing Sun, Edmund K. Moon, Luana Pereira et al. · 2010 · Molecular Therapy
29. Transfer of Heme Oxygenase 1 cDNA by a Replication-Deficient Adenovirus Enhances Interleukin 10 Production from Alveolar Macrophages That Attenuates Lipopolysaccharide-Induced Acute Lung Injury in Mice
    Satoshi Inoue, Motoyoshi Suzuki, Yoji Nagashima, Shunsuke Suzuki, Tomonori Hashiba, Takahiro Tsuburai, Kunihiko Ikehara, Takeshi Matsuse, Yoshiaki Ishigatsubo · 2001 · Human Gene Therapy
30. Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study
    Richard L. Mackman, Michael Sangi, David Sperandio, Jay P. Parrish, Eugene J. Eisenberg, Michel J. Perron, Hon C. Hui, Lijun Zhang, Dustin S. Siegel, Hai Yang et al. · 2015 · Journal of Medicinal Chemistry
31. Epidemiology of allergic rhinitis
    James “Whit” Mims · 2014 · International Forum of Allergy & Rhinology
32. Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma
    W. Roy Smythe, Larry R. Kaiser, Harry C. Hwang, Kunjlata M. Amin, Joseph M. Pilewski, Stephen Eck, James M. Wilson, Steven Μ. Albelda · 1994 · The Annals of Thoracic Surgery
33. Safety of Local Delivery of Low- and Intermediate-Dose Adenovirus Gene Transfer Vectors to Individuals with a Spectrum of Morbid Conditions
    Ben‐Gary Harvey, Jaman M. Maroni, Kelley A. O'Donoghue, Karen W Chu, Jolene C. Muscat, Allison L. Pippo, Connie E. Wright, Charleen Hollmann, Juan Pablo Wisnivesky, Paul Kessler et al. · 2002 · Human Gene Therapy
34. High levels of persistent expression of α1-antitrypsin mediated by the nonhuman primate serotype rh. 10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses
    De, Bishnu P., Heguy, Adriana, Hackett, Neil R., Ferris, Barbara, Leopold, Philip L., Lee, John, Pierre, Lorraine, Gao, Guangping, Wilson, James M., Crystal, Ronald G. · 2006 · Molecular Therapy
35. Phase I Clinical/Pharmacokinetic and Pharmacodynamic Trial of the c-raf-1 Antisense Oligonucleotide ISIS 5132 (CGP 69846A)
    James P. Stevenson, Kang-Shen Yao, Maryann Gallagher, David P. Friedland, Edith Peterson Mitchell, Amy Cassella, Brett P. Monia, T. Jesse Kwoh, Rosie Z. Yu, Jon Holmlund et al. · 1999 · Journal of Clinical Oncology
36. Broad protection against influenza infection by vectored immunoprophylaxis in mice
    Alejandro Benjamin Balazs, Jesse D. Bloom, Christin M. Hong, Dinesh S. Rao, David Baltimore · 2013 · Nature Biotechnology
37. Cystic fibrosis mice carrying the missense mutation G551D replicate human genotype‐phenotype correlations.
    Stephen J. Delaney, Eric W.F.W. Alton, S.N. Smith, Dominic P Lunn, R Farley, Paul K. Lovelock, S. A. Thomson, David Arthur Hume, D Lamb, David John Porteous et al. · 1996 · The EMBO Journal
38. A severe phenotype in mice with a duplication of exon 3 in the cystic fibrosis locus
    Wanda K. O’Neal, Paul Hasty, Paul B. McCray, Brett M. Casey, Jaime A. Rivera‐Pérez, Michael J. Welsh, Arthur L. Beaudet, Allan Bradley · 1993 · Human Molecular Genetics
39. A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer.
    Casey C. Cunningham, Jon Holmlund, Joan H. Schiller, Richard S. Geary, T. Jesse Kwoh, Andrew Dorr, John J. Nemunaitis · 2000 · PubMed
40. The suppression of lung tumorigenesis by aerosol-delivered folate–chitosan-graft-polyethylenimine/Akt1 shRNA complexes through the Akt signaling pathway
    Hu‐Lin Jiang, Cheng‐Xiong Xu, You-Kyoung Kim, Rohidas B. Arote, Dhananjay Jere, Hwang-Tae Lim, Myung‐Haing Cho, Chong‐Su Cho · 2009 · Biomaterials
41. Inhibition of Allergic Inflammation in the Airways Using Aerosolized Antisense to Syk Kinase
    Grant R. Stenton, Marina Ulanova, René E. Déry, Shaheed Merani, Moo-Kyung Kim, Mark Gilchrist, Lakshmi Puttagunta, Sorin Musat‐Marcu, Deborah James, Alan D. Schreiber et al. · 2002 · The Journal of Immunology
42. The effect of mucolytic agents on gene transfer across a CF sputum barrier in vitro
    Marc Stern, Natasha J. Caplen, J. A. Browning, Uta Griesenbach D, F Sorgi, Leaf Huang, Dieter C. Gruenert, C Marriot, RG Crystal, Duncan M Geddes et al. · 1998 · Gene Therapy
43. Enhanced Gene Expression in Mouse Lung after PEI–DNA Aerosol Delivery
    Ajay Kumar Gautam, Charles L. Densmore, Bo Xu, J. Clifford Waldrep · 2000 · Molecular Therapy
44. Therapeutic Efficacy of AAV1.SERCA2a in Monocrotaline-Induced Pulmonary Arterial Hypertension
    Lahouaria Hadri, Razmig Garo Kratlian, Ludovic Bénard, Bradley A. Maron, Peter Dorfmüller, Dennis Ladage, Christophe Guignabert, Kiyotake Ishikawa, Jaume Agüero, Borja Ibáñez et al. · 2013 · Circulation
45. Barriers to inhaled gene therapy of obstructive lung diseases: A review
    Nam‐Ho Kim, Gregg A. Duncan, Justin S. Hanes, Jung Soo Suk · 2016 · Journal of Controlled Release
46. Lentivirus Vectors Pseudotyped with Filoviral Envelope Glycoproteins Transduce Airway Epithelia from the Apical Surface Independently of Folate Receptor Alpha
    Patrick L. Sinn, Melissa A. Hickey, Patrick D. Staber, Douglas E. Dylla, Scott A. Jeffers, Beverly L. Davidson, David Avram Sanders, Paul B. McCray · 2003 · Journal of Virology
47. Ex Vivo Adenoviral Vector Gene Delivery Results in Decreased Vector-associated Inflammation Pre- and Post–lung Transplantation in the Pig
    Jonathan C. Yeung, Dirk Wagnetz, Marcelo Cypel, Matthew Rubacha, Terumoto Koike, Yi-Min Chun, Jim Hu, Thomas K. Waddell, David M. Hwang, Mingyao Liu et al. · 2012 · Molecular Therapy
48. Phase I Trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer.
    Charles M. Rudin, John T Holmlund, Gini F. Fleming, Sridhar Mani, Walter Michael Stadler, L. Philip Schumm, Brett P. Monia, Joseph F. Johnston, Richard S. Geary, Rosie Z. Yu et al. · 2001 · PubMed
49. Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism
    Mays, Lauren E., Ammon-Treiber, Susanne, Mothes, Benedikt, Alkhaled, Mohammed, Rottenberger, Jennifer, Müller-Hermelink, Eva Sophie, Grimm, Melanie, Mezger, Markus, Beer-Hammer, Sandra, von Stebut, Esther et al. · 2013 · Journal of Clinical Investigation
50. Persistent Gene Expression in Mouse Nasal Epithelia following Feline Immunodeficiency Virus-Based Vector Gene Transfer
    Patrick L. Sinn, Erin R. Burnight, Melissa A. Hickey, Gary W. Blissard, Paul B. McCray · 2005 · Journal of Virology
51. Intranasal Antibody Gene Transfer in Mice and Ferrets Elicits Broad Protection Against Pandemic Influenza
    Maria P. Limberis, Virginie S. Adam, Gary Wong, Jason Gren, Darwyn Kobasa, Ted M. Ross, Gary P. Kobinger, Anna P. Tretiakova, James M. Wilson · 2013 · Science Translational Medicine
52. Replication-restricted vaccinia as a cytokine gene therapy vector in cancer: Persistent transgene expression despite antibody generation
    Sutapa Mukherjee, Thomas Haenel, Robyn P. Himbeck, Bernadette Scott, Ian A. Ramshaw, Richard Lake, Gerry B. Harnett, Peter A. Phillips, Sue Morey, David W. Smith et al. · 2000 · Cancer Gene Therapy
53. Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model
    Andrea Mohr, Mark J. Lyons, Laura Deedigan, Tina Harte, Georgina Shaw, Linda Howard, Frank Barry, Timothy O’Brien, Ralf Michael Zwacka · 2008 · Journal of Cellular and Molecular Medicine
54. Eradication of intraperitoneal and distant tumor by adenovirus-mediated interferon-beta gene therapy is attributable to induction of systemic immunity.
    Makoto Odaka, Daniel H. Sterman, Rainer Gerhard Wiewrodt, Yi Zhang, M Kiefer, Kunjlata M. Amin, Guanping Gao, James M. Wilson, James Barsoum, Larry R. Kaiser et al. · 2001 · PubMed
55. Alpha-1-antitrypsin augmentation therapy for alpha-1-antitrypsin deficiency
    Richard C. Hubbard, Ronald G. Crystal · 1988 · The American Journal of Medicine
56. Treatment of Experimental Human Mesothelioma Using Adenovirus Transfer of the Herpes Simplex Thymidine Kinase Gene
    William Roy Smythe, Harry C. Hwang, Ashraf A. Elshami, Kunjlata M. Amin, Stephen L. Eck, Beverly L. Davidson, James M. Wilson, Larry R. Kaiser, S M Albeida · 1995 · Annals of Surgery
57. Insights into the Pathogenesis of Asthma Utilizing Murine Models
    Christian Taube, Azzeddine Dakhama, Erwin W. Gelfand · 2004 · International Archives of Allergy and Immunology
58. Assessment of F/HN-Pseudotyped Lentivirus as a Clinically Relevant Vector for Lung Gene Therapy
    Uta Griesenbach D, Makoto Inoue, Cuixiang Meng, Raymond Farley, Mario Chan, Nikki K. Newman, Andrea M. Brum, Jun You, Angela Kerton, Amelia Shoemark et al. · 2012 · American Journal of Respiratory and Critical Care Medicine
59. Therapeutic serum concentrations of human alpha-1-antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes
    Mark A. Kay, Frank L. Graham, Frances E. Leland, Savio L.C. Woo · 1995 · Hepatology
60. Effective prevention and therapy of experimental allergic asthma using a GATA-3–specific DNAzyme
    Serdar Sel, Michael Wegmann, Tanja Dicke, S. Sel, Wolfgang Henke, Ali Önder Yildirim, Harald Renz, Holger Garn · 2008 · Journal of Allergy and Clinical Immunology
61. Protection against P. aeruginosa with an adenovirus vector containing an OprF epitope in the capsid
    Stefan Worgall, Anja Krause, Michael Rivara, Kyung-Kim Hee, Enrico V. Vintayen, Neil R. Hackett, Peter W. Roelvink, Joseph T. Bruder, Thomas J. Wickham, Imre Kovesdi et al. · 2005 · Journal of Clinical Investigation
62. Pseudomonas aeruginosa infection in cystic fibrosis lung disease and new perspectives of treatment: a review
    Marisa Costa Gaspar, William R. Couet, Jean‐Christophe Olivier, Alberto A. C. C. Pais, João Sousa · 2013 · European Journal of Clinical Microbiology & Infectious Diseases
63. Human lung cancer and p53 : The interplay between mutagenesis and selection
    Sergei N. Rodin, Andrew S. Rodin · 2000 · Proceedings of the National Academy of Sciences
64. Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung
    Gerry McLachlan, Heidi M. Davidson, Emma L. Holder, L A Davies, Ian A. Pringle, Stephanie Jones, A Baker, Peter A. Tennant, C Gordon, C Vrettou et al. · 2011 · Gene Therapy
65. Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences
    Gillian Lavelle, Michelle M. White, Niall Browne, Noel Gerard McElvaney, Emer P. Reeves · 2016 · BioMed Research International
66. Allogeneic Vaccination With a B7.1 HLA-A Gene-Modified Adenocarcinoma Cell Line in Patients With Advanced Non–Small-Cell Lung Cancer
    Luis Estuardo Raez, Peter A. Cassileth, James J. Schlesselman, Kasi S. Sridhar, Swaminathan Padmanabhan, Eva Fisher, Paulette Baldie, Eckhard R. Podack · 2004 · Journal of Clinical Oncology
67. No lung toxicity after repeated aerosol or intravenous delivery of plasmid-cationic liposome complexes
    Angelo E. Canonico, J. D. Plitman, J T Conary, Barbara O. Meyrick, Kenneth L. Brigham · 1994 · Journal of Applied Physiology
68. Aerosol and Lobar Administration of a Recombinant Adenovirus to Individuals with Cystic Fibrosis. I. Methods, Safety, and Clinical Implications
    Patricia M. Joseph, Brian P. O'Sullivan, Allen Lapey, Henry L. Dorkin, Joseph Oren, Rosemary Balfour, Michael A. Perricone, Mireille Rosenberg, Samuel C. Wadsworth, Alan E. Smith et al. · 2001 · Human Gene Therapy
69. Adenovirus-mediated mda-7 (IL24) gene therapy suppresses angiogenesis and sensitizes NSCLC xenograft tumors to radiation
    Takashi Nishikawa, Rajagopal Ramesh, Anupama Munshi, Sunil Chada, Raymond E. Meyn · 2004 · Molecular Therapy
70. Gene Therapy for Oxidant Injury-Related Diseases: Adenovirus-Mediated Transfer of Superoxide Dismutase and Catalase cDNAs Protects against Hyperoxia but Not Against Ischemia–Reperfusion Lung Injury
    Claire J. Danel, SERPIL CEM ERZURUM, Paule Prayssac, N. Tony Eissa, Ronald G. Crystal, Philippe Hervé, Bruno Baudet, Michel G. Mazmanian, Patricia Lemarchand · 1998 · Human Gene Therapy
71. Hepatocyte Growth Factor Gene-Modified Mesenchymal Stem Cells Reduce Radiation-Induced Lung Injury
    Hua Wang, Yuefeng Yang, Li Zhao, Fengjun Xiao, Qunwei Zhang, Mingling Wen, Chu-Tse Wu, RuiYun PENG, Lisheng Wang · 2013 · Human Gene Therapy
72. Pilot and Feasibility Trial Evaluating Immuno-Gene Therapy of Malignant Mesothelioma Using Intrapleural Delivery of Adenovirus-IFNα Combined with Chemotherapy
    Daniel H. Sterman, Evan W. Alley, James P. Stevenson, Joseph S. Friedberg, Susan T Metzger, Adri Recio, Edmund K. Moon, Andrew R. Haas, Anil Vachani, Sharyn I. Katz et al. · 2016 · Clinical Cancer Research
73. Transfection of Nasal Mucosa with a Normal alpha 1 -Antitrypsin Gene in alpha 1 -Antitrypsin-Deficient Subjects: Comparison with Protein Therapy
    Kenneth L. Brigham, K B Lane, Barbara O. Meyrick, Arlene A. Stecenko, Stefan Strack, Dermot Cannon, Michelle Caudill, Angelo E. Canonico · 2000 · Human Gene Therapy
74. Aerosol delivery of urocanic acid–modified chitosan/programmed cell death 4 complex regulated apoptosis, cell cycle, and angiogenesis in lungs of K-ras null mice
    Hua Jin, Tae Hee Kim, Soon‐Kyung Hwang, Seung-Hee Chang, Hyun‐Woo Kim, Hanjo K. Anderson, Han-Woong Lee, Kee-Ho Lee, Nancy H. Colburn, Hsin‐Sheng Yang et al. · 2006 · Molecular Cancer Therapeutics
75. Gene Therapy using Adenovirus Carrying the Herpes Simplex-Thymidine Kinase Gene to Treat In Vivo Models of Human Malignant Mesothelioma and Lung Cancer
    Harry C. Hwang, William Roy Smythe, Ashraf A. Elshami, John C. Kucharczuk, K M Amin, J P Williams, Leslie A. Litzky, Larry R. Kaiser, Steven Μ. Albelda · 1995 · American Journal of Respiratory Cell and Molecular Biology
76. Phase I Study of a Recombinant Adenovirus-Mediated Gene Transfer in Lung Cancer Patients
    Thomas Tursz, Axel Le Cesne, Pierre Baldeyrou, E. Gautier, Paule Opolon, C. Schatz, Andréa Pavirani, M. Courtney, D. Lamy, Thierry Ragot et al. · 1996 · JNCI Journal of the National Cancer Institute
77. Allergic sensitization can be induced via multiple physiologic routes in an adjuvant-dependent manner
    David Dunkin, M. Cecilia Berin, Lloyd Mayer · 2011 · Journal of Allergy and Clinical Immunology
78. Anti-Inflammatory Activity of Inhaled IL-4 Receptor-α Antisense Oligonucleotide in Mice
    James G. Karras, Jeffrey R. Crosby, Mausumee Guha, David Tung, Doreen A. Miller, William A. Gaarde, Richard S. Geary, Brett P. Monia, Susan A. Gregory · 2006 · American Journal of Respiratory Cell and Molecular Biology
79. Pulmonary cytokine responses associated with PEI–DNA aerosol gene therapy
    Ajay Kumar Gautam, Charles L. Densmore, J. Clifford Waldrep · 2001 · Gene Therapy
80. Cystic Fibrosis Gene Therapy in the UK and Elsewhere
    Uta Griesenbach D, Kamila M Pytel, Eric W.F.W. Alton · 2015 · Human Gene Therapy
81. Enhanced In Vivo Airway Gene Transfer via Transient Modification of Host Barrier Properties with a Surface-Active Agent
    David Parsons, Barbara R. Grubb, Larry G. Johnson, Richard C. Boucher · 1998 · Human Gene Therapy
82. Lentivirus Vector Can Be Readministered to Nasal Epithelia without Blocking Immune Responses
    Patrick L. Sinn, Ariadna C. Arias, Kim Alan Brogden, Paul B. McCray · 2008 · Journal of Virology
83. Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors
    Tristan R. McKay, Manij Patel, Raymond John Pickles, Larry G. Johnson, John C. Olsen · 2006 · Gene Therapy
84. RNAi Therapeutic Platforms for Lung Diseases
    Yu Fujita, Fumitaka Takeshita, Kazuyoshi Kuwano, Takahiro Ochiya · 2013 · Pharmaceuticals
85. CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes
    Benjamin R. Steines, David D. Dickey, Jamie Bergen, Katherine J. D. A. Excoffon, John R. Weinstein, Xiaopeng Li, Ziying Yan, Mahmoud H. Abou Alaiwa, Viral S. Shah, Drake C. Bouzek et al. · 2016 · JCI Insight
86. Effective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization
    Anushi E Rajapaksa, Jenny J Ho, Aisha Qi, Robert J. Bischof, Tri‐Hung Nguyen, Michelle D. Tate, David M. Piedrafita, Michelle P. McIntosh, Leslie Y. Yeo, Els N.T. Meeusen et al. · 2014 · Respiratory Research
87. Aerosol and Lobar Administration of a Recombinant Adenovirus to Individuals with Cystic Fibrosis. II. Transfection Efficiency in Airway Epithelium
    Michael A. Perricone, James E. Morris, Karen L. Pavelka, Malinda S. Plog, Brian P. O'Sullivan, Patricia M. Joseph, Henry L. Dorkin, Allen Lapey, Rosemary Balfour, David P. Meeker et al. · 2001 · Human Gene Therapy
88. Adeno-Associated Virus Types 5 and 6 Use Distinct Receptors for Cell Entry
    Michael P. Seiler, A. Dusty Miller, Joseph Zabner, Christine L. Halbert · 2006 · Human Gene Therapy
89. Cationic lipids for reporter gene and CFTR transfer to rat pulmonary epithelium.
    James J Logan, Zsuzsa Bebők, Lynn Walker, Sydney Peng, Philip Louis Felgner, Gene P. Siegal, R. A. Frizzell, Jiahong Dong, M Howard, Matalon · 1995 · PubMed
90. Inhibition of Chronic Airway Inflammation and Remodeling by Galectin-3 Gene Therapy in a Murine Model
    Esther López, Victoria del Pozo, Teresa Miguel, Beatriz Sastre, Carmen Seoane, Esther Civantos, Elena Llanes, ML Baeza, Pilar Palomino, Blanca Cárdaba et al. · 2006 · The Journal of Immunology
91. Pulmonary Targeting of Adeno-associated Viral Vectors by Next-generation Sequencing-guided Screening of Random Capsid Displayed Peptide Libraries
    Jakob Körbelin, Timo Sieber, Stefan Michelfelder, Lars Peter Lunding, Elmar Spies, Agnes Hunger, Malik Alawi, Kleopatra Rapti, Daniela Indenbirken, Oliver Josef Müller et al. · 2016 · Molecular Therapy
92. Anti-Tumor Immunity Induced by in Vivo Adenovirus Vector-Mediated Expression of CD40 Ligand in Tumor Cells
    Toshiaki Kikuchi, Ronald G. Crystal · 1999 · Human Gene Therapy
93. Synergistic inhibition of human lung cancer cell growth by adenovirus-mediated wild-type p53 gene transfer in combination with docetaxel and radiation therapeutics in vitro and in vivo.
    M Nishizaki, R.E. Meyn, Lawrence B. Levy, Edward Neely Atkinson, R. Allen White, J A Roth, Lin Ji · 2001 · PubMed
94. Adenoviral-Mediated p53 Gene Transfer to Non-small Cell Lung Cancer Through Endobronchial Injection
    David Weill, Michael J. Mack, Jack A. Roth, Stephen G. Swisher, Scott Proksch, James Merritt, John J. Nemunaitis · 2000 · CHEST Journal
95. Humoral and cellular immune responses of nonhuman primates to long-term repeated lung exposure to Ad2/CFTR-2.
    JM Kaplan, J A St George, Pennington Se, Lynne D. KEYES, R. Paul Johnson, Samuel C. Wadsworth, Smith Ae · 1996 · PubMed
96. Long-term therapeutic levels of human alpha-1 antitrypsin in plasma after hydrodynamic injection of nonviral DNA
    Salvador Francisco Aliño, Antonio Crespo, Francisco Dası́ · 2003 · Gene Therapy
97. Efficiency of Cationic Lipid-Mediated Transfection of Polarized and Differentiated Airway Epithelial Cells In Vitro and In Vivo
    Canwen Jiang, Sean P. O'Connor, Shaona L. Fang, Kathryn X. Wang, John Marshall, Jennifer L. Williams, B. Wilburn, Yann Echelard, Seng H. Cheng · 1998 · Human Gene Therapy
98. Interleukin-10 Delivery via Mesenchymal Stem Cells: A Novel Gene Therapy Approach to Prevent Lung Ischemia–Reperfusion Injury
    Eddie W. Manning, Si M. Pham, Sen Li, Roberto I. Vázquez-Padrón, James M. Mathew, Phillip Ruiz, Shashikumar K. Salgar · 2010 · Human Gene Therapy
99. In vivo human carboxylesterase cDNA gene transfer to activate the prodrug CPT-11 for local treatment of solid tumors.
    A Kojima, Neil R. Hackett, Akihiko Ohwada, Ronald G. Crystal · 1998 · Journal of Clinical Investigation
100. The pallid mouse. A model of genetic alpha 1-antitrypsin deficiency.
     Piero A. Martorana, T Brand, Concetta Gardi, Paul van Even, M. M. De Santi, Paola Calzoni, Paola Marcolongo, Giuseppe Lungarella · 1993 · PubMed
101. Allergen‐induced murine upper airway inflammation: local and systemic changes in murine experimental allergic rhinitis
     Hiroko Saito, Karen J. Howie, Jennifer N. Wattie, Avram Denburg, Russ Ellis, Mark D. Inman, Judah A. Denburg · 2001 · Immunology
102. Phase II trial with ISIS 5132 in patients with small-cell (SCLC) and non-small cell (NSCLC) lung cancer. A European Organization for Research and Treatment of Cancer (EORTC) Early Clinical Studies Group report
     Bruno P. Coudert, Alan Anthoney, Walter Fiedler, Jean‐Pierre Droz, Veronique C Dieras, Markus Borner, John F. Smyth, R. Morant, M.J de Vries, M. Roelvink et al. · 2001 · European Journal of Cancer
103. Impaired Ability of Cftr Knockout Mice to Control Lung Infection with Pseudomonas aeruginosa
     Diane R. Gosselin, Mary M. Stevenson, Elizabeth Asenath Cowley, Uta Griesenbach D, David H. Eidelman, Marie Boulé, Mifong Tam, Geraldine M. Kent, Emil Skamene, Lap‐Chee Tsui et al. · 1998 · American Journal of Respiratory and Critical Care Medicine
104. Identification and characterization of Sulfolobus solfataricus D -gluconate dehydratase: a key enzyme in the non-phosphorylated Entner–Doudoroff pathway
     Seonghun Kim, Sun Bok Lee · 2005 · Biochemical Journal
105. Partial protection against H5N1 influenza in mice with a single dose of a chimpanzee adenovirus vector expressing nucleoprotein
     Sylvain Roy, G KOBINGER, Judy M. Lin, Joanita M. Figueredo, Roberto Calcedo, Darwyn Kobasa, James M. Wilson · 2007 · Vaccine
106. Systemic and Local Interferon gamma Gene Delivery to the Lungs for Treatment of Allergen-Induced Airway Hyperresponsiveness in Mice
     STEVEN W. DOW, Jürgen Schwarze, Timothy D. Heath, Terry A. Potter, Erwin W. Gelfand · 1999 · Human Gene Therapy
107. Adenoviral Vectors for Gene Replacement Therapy
     Huibi Cao, David R. Koehler, Jim Hu · 2004 · Viral Immunology
108. Comparison between intratracheal and intravenous administration of liposome–DNA complexes for cystic fibrosis lung gene therapy
     Uta Griesenbach D, Arcadio Chonn, R Cassady, Vicky Hannam, CA Ackerley, Martin Post, A. Keith Tanswell, K. Olek, Hugh M O'Brodovich, LC Tsui · 1998 · Gene Therapy
109. Multicenter Phase I Study of Repeated Intratumoral Delivery of Adenoviral p53 in Patients With Advanced Non–Small-Cell Lung Cancer
     Toshiyoshi Fujiwara, Noriaki Tanaka, Susumu Kanazawa, Shoichiro Ohtani, Yasuo Saijo, Toshihiro Nukiwa, Kunihiko Yoshimura, Tetsuo Satō, Yoshikatsu Eto, Sunil Chada et al. · 2006 · Journal of Clinical Oncology
110. Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia
     David R. Koehler, Umadevi S. Sajjan, Yu‐Hua Chow, Bernard G. Martin, Geraldine M. Kent, A. Keith Tanswell, Colin McKerlie, J. Forstner, Jim Hu · 2003 · Proceedings of the National Academy of Sciences
111. A novel cationic lipid with intrinsic antitumor activity to facilitate gene therapy of TRAIL DNA
     Cong Luo, Lei Miao, Yi D. Zhao, Sara Musetti, Yuhua Wang, Kai Shi, Leaf Huang · 2016 · Biomaterials
112. Synergistic effects of co-administration of suicide gene expressing mesenchymal stem cells and prodrug-encapsulated liposome on aggressive lung melanoma metastases in mice.
     Tian-Yuan Zhang, Bing Huang, Hai-Bin Wu, Jia-He Wu, Li-Ming Li, Yanxuan Li, Yu-Lan Hu, Min Han, You-Qing Shen, Y. Tabata et al. · 2015 · Journal of Controlled Release
113. Transfer of the CFTR Gene to the Lung of Nonhuman Primates with E1-Deleted, E2a-Defective Recombinant Adenoviruses: A Preclinical Toxicology Study
     Mitchell J. Goldman, Leslie A. Litzky, John F. Engelhardt, James M. Wilson · 1995 · Human Gene Therapy
114. CFTR, bicarbonate, and the pathophysiology of cystic fibrosis
     Drucy Borowitz · 2015 · Pediatric Pulmonology
115. Electroporation-mediated Gene Transfer of the Na + ,K + -ATPase Rescues Endotoxin-induced Lung Injury
     Gökhan M. Mutlu, David Machado-Aranda, James E. Norton, Amy Bellmeyer, Daniela Urich, Rui Zhou, David A. Dean · 2007 · American Journal of Respiratory and Critical Care Medicine
116. GOLGA2/GM130, cis-Golgi Matrix Protein, is a Novel Target of Anticancer Gene Therapy
     Seung-Hee Chang, Seong‐Ho Hong, Hu‐Lin Jiang, Arash Minai‐Tehrani, Kyeong‐Nam Yu, Jae‐Ho Lee, Ji‐Eun Kim, Jiyoung Shin, Bitna Kang, Sung Jin Park et al. · 2012 · Molecular Therapy
117. Plague: A Review of its History and Potential as a Biological Weapon
     B. Lee Ligon · 2006 · Seminars in Pediatric Infectious Diseases
118. Analysis of Risk Factors for Local Delivery of Low- and Intermediate-Dose Adenovirus Gene Transfer Vectors to Individuals with a Spectrum of Comorbid Conditions
     Ronald G. Crystal, Ben‐Gary Harvey, Juan Pablo Wisnivesky, Kelley A. O'Donoghue, Karen W Chu, Jaman M. Maroni, Jolene C. Muscat, Allison L. Pippo, Connie E. Wright, Robert J. Kaner et al. · 2002 · Human Gene Therapy
119. Reduced inflammation and improved airway expression using Helper-Dependent adenoviral vectors with a k18 promoter
     Gabriele Toietta, David R. Koehler, Milton J. Finegold, Brendan Lee, Jim Hu, Arthur L. Beaudet · 2003 · Molecular Therapy
120. Production of viral vectors for gene therapy applications
     Naxin Wu, Mohammad M. Ataai · 2000 · Current Opinion in Biotechnology
121. Pseudotyped Lentivirus Vectors Derived from Simian Immunodeficiency Virus SIVagm with Envelope Glycoproteins from Paramyxovirus
     Masanori Kobayashi, Akihiro Iida, Yasuji Ueda, Mamoru Hasegawa · 2003 · Journal of Virology
122. Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno‐associated virus (rAAV1) vector
     Yuanqing Lu, Young‐Kook Choi, Martha Campbell‐Thompson, Chengwen Li, Qiushi Tang, James M. Crawford, Terence R. Flotte, Sihong Song · 2006 · The Journal of Gene Medicine
123. Intratracheal Gene Delivery of SERCA2a Ameliorates Chronic Post-Capillary Pulmonary Hypertension
     Jaume Agüero, Kiyotake Ishikawa, Lahouaria Hadri, Carlos G. Santos‐Gallego, Kenneth Michael Fish, Erik Kohlbrenner, Nadjib Hammoudi, Changwon Kho, Ahyoung Lee, Borja Ibáñez et al. · 2016 · Journal of the American College of Cardiology
124. WT1 gene silencing by aerosol delivery of PEI–RNAi complexes inhibits B16-F10 lung metastases growth
     Diana Elisa Zamora-Ávila, Pablo Zapata‐Benavides, Moisés Ármides Franco-Molina, Santiago Saavedra-Alonso, Laura M Trejo-Avila, Diana Reséndez‐Pérez, José L. Méndez-Vázquez, J Isaias-Badillo, Cristina Rodrı́guez-Padilla · 2009 · Cancer Gene Therapy
125. Transbronchial administration of adenoviral-mediated interleukin-10 gene to the donor improves function in a pig lung transplant model
     Saulo Martins, Marc E. de Perrot, Yoichi Imai, Masaomi Yamane, Syed Mohiuddin Quadri, Lorne Segall, André Dutly, Shoji Sakiyama, Adriana Chaparro, Beverly L. Davidson et al. · 2004 · Gene Therapy
126. Food Allergy Animal Models
     Ricki M. Helm · 2002 · Annals of the New York Academy of Sciences
127. rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice
     Vidović, Dragana, Carlon, Marianne S., da Cunha, Mélanie F., Dekkers, Johanna F., Hollenhorst, Monika I., Bijvelds, Marcel J. C., Ramalho, Anabela S., Van den Haute, Chris, Ferrante, Marc, Baekelandt, Veerle et al. · 2016 · American Journal of Respiratory and Critical Care Medicine
128. Safety of Adenovirus-Mediated Transfer of the Human Cystic Fibrosis Transmembrane Conductance Regulator cDNA to the Lungs of Nonhuman Primates
     Robert William Wilmott, Raouf Samy Amin, Carlos Ramírez Pérez, Susan E. Wert, G.L. Keller, Gregory P. Boivin, Raphael Hirsch, Jaime de Inocencio Arocena, Patrick Y. Lu, Shirley F. Reising et al. · 1996 · Human Gene Therapy
129. Adenovirus-mediated transfer of the 1-cys peroxiredoxin gene to mouse lung protects against hyperoxic injury
     Yan Wang, Yefim Manevich, Sheldon I. Feinstein, Aron B. Fisher · 2004 · American Journal of Physiology-Lung Cellular and Molecular Physiology
130. Intrapleural Administration of AAV9 Improves Neural and Cardiorespiratory Function in Pompe Disease
     Darin J. Falk, Cathryn S. Mah, Meghan S. Soustek, Kun‐Ze Lee, Mai K. ElMallah, Denise A Cloutier, David Dwight Fuller, Barry J. Byrne · 2013 · Molecular Therapy
131. GENE THERAPY FOR MALIGNANT PLEURAL MESOTHELIOMA
     Daniel H. Sterman, Larry R. Kaiser, Steven Μ. Albelda · 1998 · Hematology/Oncology Clinics of North America
132. Polyethylenimine-mediated gene delivery to the lung and therapeutic applications
     Massimo Conese · 2008 · Drug Design Development and Therapy
133. Aerosol delivery of PEI–p53 complexes inhibits B16-F10 lung metastases through regulation of angiogenesis
     Ajay Kumar Gautam, Charles L. Densmore, Sara Melton, Eva Golunski, J. Clifford Waldrep · 2002 · Cancer Gene Therapy
134. Small Interfering RNA against Transcription Factor STAT6 Inhibits Allergic Airway Inflammation and Hyperreactivity in Mice
     Yasemin Darcan, Holger Meinicke, Gabriele Fels, Olga Hegend, Annekathrin Haberland, Anja Andrea Kühl, Christoph Loddenkemper, Martin Witzenrath, S Kube, Wolfgang Henke et al. · 2009 · The Journal of Immunology
135. Administration of antisense phosphorothioate oligonucleotide to the p65 subunit of NF-κB inhibits established asthmatic reaction in mice
     Il‐Whan Choi, Dae‐Ki Kim, Hyun‐Mi Ko, Hern-Ku Lee · 2004 · International Immunopharmacology
136. Lentiviral-mediated GATA-3 RNAi decreases allergic airway inflammation and hyperresponsiveness
     Lee, Chen-Chen, Huang, Hsin-Ying, Chiang, Bor-Luen · 2008 · Molecular Therapy
137. Effective Treatment of Early Endobronchial Cancer With Regional Administration of Liposome-p53 Complexes
     Y. Zou, G. Zong, Y.-H. Ling, M. M. Hao, Guillermina Lozano, Waun Ki Hong, Roman Perez-Soler · 1998 · JNCI Journal of the National Cancer Institute
138. Role of E4 in Eliciting CD4 T-Cell and B-Cell Responses to Adenovirus Vectors Delivered to Murine and Nonhuman Primate Lungs
     Narendra B. Chirmule, Joseph V. Hughes, Guangping Gao, Steven E. Raper, James M. Wilson · 1998 · Journal of Virology
139. Current Status of Gene Therapy for Inherited Lung Diseases
     Ryan R. Driskell, John F. Engelhardt · 2003 · Annual Review of Physiology
140. Functional Characterization of a Recombinant Adeno- Associated Virus 5-Pseudotyped Cystic Fibrosis Transmembrane Conductance Regulator Vector
     Jeffrey R. Sirninger, Christian R. Müller, Sofia A. Braag, Qiushi Tang, Hungwen Yue, Carol J. Detrisac, Thomas W. Ferkol, William B. Guggino, Terence R. Flotte · 2004 · Human Gene Therapy
141. Immunological hurdles to lung gene therapy
     Stefano Ferrari, Uta Griesenbach D, Duncan M Geddes, Eric W.F.W. Alton · 2003 · Clinical & Experimental Immunology
142. Phase I Trial of Sequential Administration of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non-Small-Cell Lung Cancer
     John J. Nemunaitis, Thomas P. Meyers, Neil N. Senzer, Casey C. Cunningham, Howard West, Eric Vallières, Stephen Patrick Anthony, Svetislava J. Vukelja, Barry S. Berman, Heather Tully et al. · 2006 · Molecular Therapy
143. Oral administration of an adenovirus vector encoding both an avian influenza A hemagglutinin and a TLR3 ligand induces antigen specific granzyme B and IFN-γ T cell responses in humans
     Wendy Peters, Jennifer R. Brandl, Jonathan D. Lindbloom, Carlos Martínez, Ciaran D. Scallan, George R. Trager, Debora W. Tingley, Martin L. Kabongo, Sean N. Tucker · 2013 · Vaccine
144. Growth suppression of established human osteosarcoma lung metastases in mice by aerosol gene therapy with PEI– p53 complexes
     Charles L. Densmore, Eugenie S. Kleinerman, Ajay Kumar Gautam, Shu-Fang Jia, Bo Xu, Laura L. Worth, J. Clifford Waldrep, Y K Fung, Anne Tang, Vernon Knight · 2001 · Cancer Gene Therapy
145. Cationic lipid:bacterial DNA complexes elicit adaptive cellular immunity in murine intraperitoneal tumor models.
     M Lanuti, Samantha Rudginsky, Seth Daniel Force, E.S. Lambright, William Siders, Michael Y. Chang, K M Amin, Larry R. Kaiser, Ronald K. Scheule, Steven Μ. Albelda · 2000 · PubMed
146. Functional Evidence of CFTR Gene Transfer in Nasal Epithelium of Cystic Fibrosis Mice in Vivo Following Luminal Application of DNA Complexes Targeted to the Serpin-Enzyme Complex Receptor
     Assem G. Ziady, Thomas J. Kelley, Erin L. Milliken, Thomas W. Ferkol, Pamela B. Davis · 2002 · Molecular Therapy
147. Gene and cell therapy for cystic fibrosis: From bench to bedside
     Massimo Conese, Fiorentina Ascenzioni, Alan Boyd, Charles C Coutelle, Ida De Fino, Stefaan C. De Smedt, Joanna Rejman, Joseph Rosenecker, Dirk Schindelhauer, Bob J. Scholte · 2011 · Journal of Cystic Fibrosis
148. Single‐dose lentiviral gene transfer for lifetime airway gene expression
     Alice G. Stocker, Karlea L. Kremer, Rachel M. Koldej, Darren S. Miller, Donald S. Anson, David Parsons · 2009 · The Journal of Gene Medicine
149. Principles of Molecular Medicine
     Marschall S. Runge, Cam Patterson · 2006 · Humana Press eBooks
150. Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter
     David R. Koehler, Helena Frndova, Kitty Leung, Emily Louca, Donna J Palmer, Philip Ng, Colin McKerlie, Peter G.F. Cox, Allan L. Coates, Jim Hu · 2005 · The Journal of Gene Medicine
151. Vaccinia as a vector for gene delivery
     Z. Sheng Guo, David L. Bartlett · 2004 · Expert Opinion on Biological Therapy
152. TPI ASM8 reduces eosinophil progenitors in sputum after allergen challenge
     H. Imaoka, H. Campbell, Irene Babirad, R. M. Watson, M. Mistry, Roma Sehmi, Gail M. Gauvreau · 2011 · Clinical & Experimental Allergy
153. Untitled work
     2003 · PubMed
154. Pulmonary Gene Delivery Using Polymeric Nonviral Vectors
     Olivia M. Merkel, Mengyao Zheng, Heiko Debus, Thomas Kissel · 2011 · Bioconjugate Chemistry
155. Lumacaftor and ivacaftor in the management of patients with cystic fibrosis: current evidence and future prospects
     Kelly N. Kuk, Jennifer L. Taylor‐Cousar · 2015 · Therapeutic Advances in Respiratory Disease
156. Antivector and antitransgene host responses in gene therapy.
     Neil R. Hackett, Stephen M. Kaminsky, Dolan Sondhi, Ronald G. Crystal · 2000 · PubMed
157. Tularemia Pneumonia
     Lora D. Thomas, William Schaffner · 2010 · Infectious Disease Clinics of North America
158. Gene Therapy with Helper-Dependent Adenoviral Vectors: Current Advances and Future Perspectives
     Francesco Vetrini, Philip Ng · 2010 · Viruses
159. Combination wt-p53 and MicroRNA-125b Transfection in a Genetically Engineered Lung Cancer Model Using Dual CD44/EGFR-targeting Nanoparticles
     Meghna Talekar, Malav Suchin Trivedi, Parin Shah, Qijun Ouyang, Adwait Oka, Srujan Kumar Gandham, Mansoor M. Amiji · 2015 · Molecular Therapy
160. Sendai virus-mediated CFTR gene transfer to the airway epithelium
     Ferrari, S, Griesenbach, U, Iida, A, Farley, R, Wright, A M, Zhu, J, Munkonge, F M, Smith, S N, You, J, Ban, H et al. · 2007 · Gene Therapy
161. Protective Immunity Evoked Against Anthrax Lethal Toxin After a Single Intramuscular Administration of an Adenovirus-Based Vaccine Encoding Humanized Protective Antigen
     Yadi Tan, Neil R. Hackett, Julie L. Boyer, Ronald G. Crystal · 2003 · Human Gene Therapy
162. Enhancing rAAV vector expression in the lung
     Isabel Virella‐Lowell, Benjamin D. Zusman, Kevin D. Foust, Scott Loiler, Thomas J. Conlon, Sihong Song, Kye A. Chesnut, Thomas W. Ferkol, Terence R. Flotte · 2005 · The Journal of Gene Medicine
163. Cytokine Gene Therapy or Infusion as Treatment for Solid Human Cancer
     Bruce W.S. Robinson, Sutapa Mukherjee, Andrew Davidson, Susan Morey, Arthur William Musk, Ian A. Ramshaw, David W. Smith, Richard Lake, Thomas Haenel, Michael J. Garlepp et al. · 1998 · Journal of Immunotherapy
164. AAVrh.10-mediated genetic delivery of bevacizumab to the pleura to provide local anti-VEGF to suppress growth of metastatic lung tumors
     Masaki Watanabe, Julie L. Boyer, Ronald G. Crystal · 2010 · Gene Therapy
165. Airway wall remodeling in asthma: From the epithelial layer to the adventitia
     Ynuk Bossé, Peter D. Paré, Chun Yong Seow · 2008 · Current Allergy and Asthma Reports
166. Protective Immunity toPseudomonas aeruginosaInduced with a Capsid-Modified Adenovirus ExpressingP. aeruginosaOprF
     Stefan Worgall, Anja Krause, Jianping Qiu, Ju Joh, Neil R. Hackett, Ronald G. Crystal · 2007 · Journal of Virology
167. Effects of overexpression of IL-10, IL-12, TGF-β and IL-4 on allergen induced change in bronchial responsiveness
     Chi‐Ling Fu, Yi-Ling Ye, Yueh‐Lun Lee, Bor‐Luen Chiang · 2006 · Respiratory Research
168. Inhibition of Experimental Lung Metastasis by Aerosol Delivery of PEI–p53 Complexes
     Ajay Kumar Gautam, Charles L. Densmore, J. Clifford Waldrep · 2000 · Molecular Therapy
169. CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo
     Lynda S. Ostedgaard, Joseph Zabner, Daniel W. Vermeer, Tatiana Rokhlina, Philip H. Karp, Arlene A. Stecenko, Christoph O. Randak, Michael J. Welsh · 2002 · Proceedings of the National Academy of Sciences
170. In Vivo Transtracheal Adenovirus-Mediated Transfer of Human Interleukin-10 Gene to Donor Lungs Ameliorates Ischemia-Reperfusion Injury and Improves Early Posttransplant Graft Function in the Rat
     Stefan Fischer, Mingyao Liu, Alexandra A. MacLean, Marc E. de Perrot, Michael Y. Ho, Jonathan A. Cardella, Xiaoming Zhang, Xiao-Hui Bai, Michiharu Suga, Yumiko Imai et al. · 2001 · Human Gene Therapy
171. Intranasal IFN-γ gene transfer protects BALB/c mice against respiratory syncytial virus infection
     Mukesh Kumar · 1999 · Vaccine
172. Efficient hepatic delivery and expression from a recombinant adeno-associated virus 8 pseudotyped alpha1-antitrypsin vector.
     T. Conlon, Travis L Cossette, Kirsten E. Erger, Young-Kook Choi, T. Clarke, Marda Scott-Jorgensen, Si-Hong Song, M. Campbell-Thompson, J. Crawford, T. Flotte · 2005 · Molecular Therapy
173. Animal Models of Malignant Mesothelioma
     Agnes B. Kane · 2006 · Inhalation Toxicology
174. Knocking Down Cav1 Calcium Channels Implicated in Th2 Cell Activation Prevents Experimental Asthma
     Marilena Djata Cabral, Pierre-Emmanuel Paulet, Virginie Robert, Bruno Duarte Gomes, Marie-Laure Renoud, Magali Savignac, Catherine Leclerc, Marc Moreau, David Lair, Marie Langelot et al. · 2010 · American Journal of Respiratory and Critical Care Medicine
175. Preclinical Evaluation of a Recombinant Adeno-Associated Virus Vector Expressing Human Alpha-1 Antitrypsin Made Using a Recombinant Herpes Simplex Virus Production Method
     Jeffrey David Chulay, Guo-jie Ye, Darby L. Thomas, David R. Knop, Janet M. Benson, Julie A. Hutt, Gensheng Wang, Margaret R. Humphries, Terence R. Flotte · 2010 · Human Gene Therapy
176. Development of cationic liposome formulations for intratracheal gene therapy of early lung cancer
     Yiyu Zou, Gang Zong, Yi‐He Ling, Roman Perez-Soler · 2000 · Cancer Gene Therapy
177. Animal models of bronchial asthma
     Istvan Szelenyi · 2000 · Inflammation Research
178. Intrapleural administration of a serotype 5 adeno-associated virus coding for α1-antitrypsin mediates persistent, high lung and serum levels of α1-antitrypsin
     Bishnu P. De, Adriana Heguy, Philip L. Leopold, Nabil Wasif, Robert J. Korst, Neil R. Hackett, Ronald G. Crystal · 2004 · Molecular Therapy
179. Eradication of osteosarcoma lung metastases following intranasal interleukin-12 gene therapy using a nonviral polyethylenimine vector
     Shu-Fang Jia, Laura L. Worth, Charles L. Densmore, Bo Xu, Zhichao Zhou, Eugenie S. Kleinerman · 2002 · Cancer Gene Therapy
180. Emerging therapies for food allergy
     Corinne Allison Keet, Robert A. Wood · 2014 · Journal of Clinical Investigation
181. Dual Reporter Comparative Indexing of rAAV Pseudotyped Vectors in Chimpanzee Airway
     Terence R. Flotte, Anne C. Fischer, Jason E. Goetzmann, Christian Mueller, Liudmila Cebotaru, Ziying Yan, Lili Wang, James M. Wilson, William B. Guggino, John F. Engelhardt · 2009 · Molecular Therapy
182. Aerosol Delivery of Glucosylated Polyethylenimine/Phosphatase and Tensin Homologue Deleted on Chromosome 10 Complex Suppresses Akt Downstream Pathways in the Lung of K- ras Null Mice
     Hyun Woo Kim, In‐Kyu Park, Chong Su Cho, Kee Ho Lee, George R. Beck, Nancy H. Colburn, Myung‐Haing Cho · 2004 · Cancer Research
183. Gene therapy of experimental malignant mesothelioma using adenovirus vectors encoding the HSVtk gene
     M.C. Esandi, GD van Someren, A J P E Vincent, DW van Bekkum, D. Valerio, Abraham Bout, J.L. Noteboom · 1997 · Gene Therapy
184. Urocanic acid-modified chitosan-mediated PTEN delivery via aerosol suppressed lung tumorigenesis in K-rasLA1 mice
     H Jin, Xu Cx, HW Kim, Y-S Chung, J-Y Shin, S-H Chang, S-J Park, E-S. Lee, S-K Hwang, J-T Kwon et al. · 2008 · Cancer Gene Therapy
185. Expression of a Truncated Cystic Fibrosis Transmembrane Conductance Regulator with an AAV5-pseudotyped Vector in Primates
     Anne C. Fischer, Carolina I Smith, Liudmila Cebotaru, Xuemei Zhang, Frederic Barton Askin, Jerry Wright, Sandra E. Guggino, Robert J. Adams, Terence R. Flotte, William B. Guggino · 2007 · Molecular Therapy
186. Immuno-gene therapy with interferon-β before surgical debulking delays recurrence and improves survival in a murine model of malignant mesothelioma
     Robert J. Kruklitis, Sunil Kumar Singhal, Peter A. DeLong, Veena Kapoor, Daniel H. Sterman, Larry R. Kaiser, Steven Μ. Albelda · 2004 · Journal of Thoracic and Cardiovascular Surgery
187. Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV
     Skaricic, Davor, Traube, Chani, De, Bishnu, Joh, Ju, Boyer, Julie, Crystal, Ronald G., Worgall, Stefan · 2008 · Virology
188. Respiratory syncytial virus infection in Fischer 344 rats is attenuated by short interfering RNA against the RSV-NS1 gene.
     Xiaoyuan Kong, Weidong Zhang, Richard F. Lockey, Alexander Auais, Giovanni Piedimonte, Shyam S. Mohapatra · 2007 · Genetic Vaccines and Therapy
189. Gene Therapy for Pulmonary Diseases
     Martin R.J. Kolb, Gail E. M. Martin, Maria Fe C. Medina, Kjetil Ask, Jack Gauldie · 2006 · CHEST Journal
190. α1‐antitrypsin deficiency and liver disease
     P. Birrer, Noel Gerard McElvaney, L. M. Chang‐Stroman, Ronald G. Crystal · 1991 · Journal of Inherited Metabolic Disease
191. Suppression of Lung Tumor Growth and Metastasis in Mice by Adeno-Associated Virus-Mediated Expression of Vasostatin
     Ke Xia Cai, Lai Ying Tse, Carly Leung, Paul K.H. Tam, Ruian Xu, Mai Har Sham · 2008 · Clinical Cancer Research
192. Lentivirus-mediated gene transfer to the respiratory epithelium: a promising approach to gene therapy of cystic fibrosis
     Elena Copreni, Marianna Penzo, Salvatore Carrabino, Massimo Conese · 2004 · Gene Therapy
193. Induction of Protective Immunity to Anthrax Lethal Toxin with a Nonhuman Primate Adenovirus-Based Vaccine in the Presence of Preexisting Anti-Human Adenovirus Immunity
     Masahiko Hashimoto, Julie L. Boyer, Neil R. Hackett, James M. Wilson, Ronald G. Crystal · 2005 · Infection and Immunity
194. Intrapleural Administration of an AAVrh.10 Vector Coding for Human α1-Antitrypsin for the Treatment of α1-Antitrypsin Deficiency
     Marı́a J. Chiuchiolo, Stephen M. Kaminsky, Dolan Sondhi, Neil R. Hackett, Jonathan B. Rosenberg, Esther Z. Frenk, Yihharn Hwang, Benjamin G. Van de Graaf, Julie A. Hutt, Gensheng Wang et al. · 2013 · Human Gene Therapy Clinical Development
195. Inhibition of Acidic Mammalian Chitinase by RNA Interference Suppresses Ovalbumin-Sensitized Allergic Asthma
     Ching‐Jen Yang, Yu‐Kuo Liu, Chao‐Lin Liu, Chia‐Ning Shen, Ming‐Ling Kuo, Chien-Chang Su, Ching‐Ping Tseng, Tzu‐Chen Yen, Chia‐Rui Shen · 2009 · Human Gene Therapy
196. Recombinant AAV Serotype and Capsid Mutant Comparison for Pulmonary Gene Transfer of α-1-Antitrypsin Using Invasive and Noninvasive Delivery
     Rejean Liqun Wang, Thomas McLaughlin, Travis L. Cossette, Qiushi Tang, Kevin D. Foust, Martha Campbell‐Thompson, Ashley T. Martino, Pedro E. Cruz, Scott Loiler, Christian Mueller et al. · 2008 · Molecular Therapy
197. Enhanced tumor suppression by adenoviral PTEN gene therapy combined with cisplatin chemotherapy in small-cell lung cancer
     DE-CHUN LI, Yao Zhang, Yu Xie, J Xiang, Yao Zhu, Jianhua Yang · 2013 · Cancer Gene Therapy
198. Asthma and allergy in alpha-1 antitrypsin deficiency
     Edward Eden, Charlie Strange, Brian Holladay, Lianqi Xie · 2006 · Respiratory Medicine
199. Current and future treatment options for cystic fibrosis lung disease: latest evidence and clinical implications
     Claire L. Edmondson, Jane Carolyn Davies · 2016 · Therapeutic Advances in Chronic Disease
200. Aerosol Delivery of Lipid:DNA Complexes to Lungs of Rhesus Monkeys
     Ruth J. McDonald, Denny Liggitt, Lisa M. Roche, Hung T. Nguyen, Rodney Pearlman, Otto G. Raabe, Lee B. Bussey, Cornelia M. Gorman · 1998 · Pharmaceutical Research