The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Isothiocyanate from Broccoli, Sulforaphane, and Its Properties
Open accessAbstract
Sulforaphane is an isothiocyanate occurring in stored form as glucoraphanin in cruciferous vegetables such as cabbage, cauliflower, and kale, and at high levels in broccoli especially in broccoli sprouts. Glucoraphanin requires the plant enzyme myrosinase for converting it into sulforaphane. Sulforaphane is metabolized through mercapturic acid pathway, being conjugated with glutathione and undergoes further biotransformation, yielding metabolites. Sulforaphane is extensively investigated and is in the interest in medicine for its health benefits. It has been shown that sulforaphane may protect against various types of cancer, may also decrease the risk of cardiovascular disease, and help in autism and osteoporosis. Our review offers a short summary of interesting properties of sulforaphane. Both the in vitro and in vivo methods/models and clinical studies are mentioned.
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Cites
The chemical diversity and distribution of glucosinolates and isothiocyanates among plants
Fahey, J. W., Zalcmann, A. T., & Talalay, P. (2001) · Phytochemistry · doi:10.1016/s0031-9422(00)00316-2 · Cited by 2,964
Neuroglial activation and neuroinflammation in the brain of patients with autism
Vargas, D. L., Nascimbene, C., Krishnan, C., Zimmerman, A. W., & Pardo, C. A. (2005) · Annals of Neurology · doi:10.1002/ana.20315 · Cited by 2,149
Zhang, Y., Talalay, P., Cho, C. G., & Posner, G. H. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.6.2399 · Cited by 1,682
Fahey, J. W., Zhang, Y., & Talalay, P. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.19.10367 · Cited by 1,376
James, S. J., Cutler, P., Melnyk, S., Jernigan, S., Janak, L., Gaylor, D. W., & Neubrander, J. A. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/80.6.1611 · Cited by 955
Cytochromes P450 and metabolism of xenobiotics
Anzenbacher, P., & Anzenbacherová, E. (2001) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000897 · Cited by 889
Self-citationLown, K. S., Bailey, D. G., Fontana, R. J., Janardan, S. K., Adair, C. H., Fortlage, L. A., Brown, M. B., Guo, W., & Watkins, P. B. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119439 · Cited by 624
Glucosinolates and isothiocyanates in health and disease
Dinkova-Kostova, A. T., & Kostov, R. V. (2012) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2012.04.003 · Cited by 605
Interaction of citrus juices with felodipine and nifedipine
Bailey, D., Spence, J., Munoz, C., & Arnold, J. M. O. (1991) · The Lancet · doi:10.1016/0140-6736(91)90872-m · Cited by 596
Antioxidant Functions of Sulforaphane: a Potent Inducer of Phase II Detoxication Enzymes
Fahey, J. W., & Talalay, P. (1999) · Food and Chemical Toxicology · doi:10.1016/s0278-6915(99)00082-4 · Cited by 482
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Tossetta, G., & Marzioni, D. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106365 · Cited by 115
Metadata
- Authors
- Vanduchova, A., Anzenbacher, P., & Anzenbacherova, E.
- Venue
- Journal of Medicinal Food
- Publisher
- SAGE Publications
- Published
- 2019-02
- Volume
- 22
- Issue
- 2
- Pages
- 121-126
- ISSN
- 1096-620X (ISSN-L)
- 1557-7600
- OpenAlex
- W2899111175
- Cited by
- 322
- References
- 45
- FWCI
- 5.73
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Vanduchova, A., Anzenbacher, P., & Anzenbacherova, E. (2019). Isothiocyanate from Broccoli, Sulforaphane, and Its Properties. Journal of Medicinal Food. https://doi.org/10.1089/jmf.2018.0024
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
