Cited by 34Thyroid Disorders and TreatmentsThyroid and Parathyroid SurgeryThyroid Cancer Diagnosis and Treatment

Unusual malabsorption of levothyroxine

Jauk, B., Mikosch, P., Gallowitsch, H.J., Kresnik, E., Molnar, M., Gomez, I., Lind, P.·2000·Thyroid

Abstract

We report a 50-year-old woman, with overt hypothyroidism undergoing thyrotropin (TSH)-stimulating hormone suppressive levothyroxine (LT4) treatment after subtotal thyroidectomy. At her first visit to our department, the laboratory results revealed a borderline low free thyroxine (FT4) level accompanied by a clearly elevated TSH level. Both parameters did not significantly change during therapy with an oral dose of 500 microg of LT4. Investigations revealed malabsorption of oral administrated LT4. Thyroid serum hormone levels only became normal during parenteral therapy with LT4.

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Crossref · 10.1089/thy.2000.10.93

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  • Unusual administration routes, including intravenous (IV) injection and IM injection, can also decrease unsuppressed TSH levels in patients with digestive tract disorders.

    “Unusual administration routes, including intravenous (IV) injection and IM injection, can also decrease unsuppressed TSH levels in patients with digestive tract disorders (55, 58, 68, 69).”

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References 10 · Cited by 34

Authors
Jauk, B., Mikosch, P., Gallowitsch, H. J., Kresnik, E., Molnar, M., Gomez, I., & Lind, P.
Affiliations
Klinikum Klagenfurt (AT)
Venue
Thyroid
Published
2000-01
Volume
10
Issue
1
Pages
93-95
ISSN
  • 1050-7256 (ISSN-L)
  • 1557-9077
OpenAlex
W2062750791
Cited by
34
References
10
Citations by year
2026: 1 · 2023: 3 · 2022: 2 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 4 · 2016: 1 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 2
FWCI
1.21
Type
journal article
Language
en
Open access
closed
Locations
  • Thyroid (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
  • Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
Keywords
overt hypothyroidism, subtotal thyroidectomy, free thyroxine, thyroid-stimulating hormone, drug absorption
MeSH terms
Administration, Oral, Carcinoma, Papillary, Female, Humans, Hypothyroidism, Infusions, Parenteral, Malabsorption Syndromes, Middle Aged, Thyroid Gland, Thyroid Neoplasms, Thyroidectomy, Thyrotropin, Thyroxine, Triiodothyronine

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