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The Principles of Life
Abstract
What is life? What are the essential differences between the living and non-living systems? The exact scientific answers to these ancient questions are indispensable preconditions for the understanding of the origins of life, for the artificial synthesis of living systems, but also for some important social problems, such as the beginning and the end of the human life. Based on the author's theory of fluid (chemical) automata, this book proves that all living systems are basically program-controlled, self-reproducing fluid automata, and that such automata behave as living systems. The simplest such construction — the chemoton — behaves as living, and all living systems have chemoton-type organization. This means that the chemoton model is the minimum model of life. The technical details have been published elsewhere: in this volume the logical train of thought is presented in a clear and easily understandable manner. The first part gives a general view of the idea; the second shows its application to the biogenesis; and the third gives the background of the theory in the natural philosophy of sciences. The author's chemical perspective captures the fundamentally cyclic organization of the living state, offers a fresh approach to the ancient problem of life criteria, and articulates a philosophy of the units of life applicable to genetics, chemistry, evolutionary biology, and exact theoretical biology. New notes throughout the text bring this legacy into dialogue with current thought in biology and philosophy.
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“It is worth noting that the SCM was the first model to explicitly assume all three subsystems of cellular organization and thus life, as defined by the Chemoton model [100,101,102]: it deals with the competition of different information carrying templates, while assuming an unspecified metabolism and a boundary subsystem that encloses the composition.”
From Ecology and Evolution in the RNA World Dynamics and Stability of Prebiotic Replicator Systems (2017) · cites this paper as [101]
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A vesicle bioreactor as a step toward an artificial cell assembly
Noireaux, V., & Libchaber, A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408236101 · Cited by 1,152
Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism
Patel, B. H., Percivalle, C., Ritson, D. J., Duffy, C. D., & Sutherland, J. D. (2015) · Nature Chemistry · doi:10.1038/nchem.2202 · Cited by 949
Prebiotic Systems Chemistry: New Perspectives for the Origins of Life
Ruiz-Mirazo, K., Briones, C., & de la Escosura, A. (2014) · Chemical Reviews · doi:10.1021/cr2004844 · Cited by 930
Autopoiesis, Adaptivity, Teleology, Agency
Di Paolo, E. A. (2005) · Phenomenology and the Cognitive Sciences · doi:10.1007/s11097-005-9002-y · Cited by 806
Kurihara, K., Tamura, M., Shohda, K.-I., Toyota, T., Suzuki, K., & Sugawara, T. (2011) · Nature Chemistry · doi:10.1038/nchem.1127 · Cited by 559
Metadata
- Authors
- Ganti, T.
- Venue
- Oxford University Press eBooks
- Publisher
- Oxford University Press
- Published
- 2003-09-18
- OpenAlex
- W1548526721
- Cited by
- 490
- References
- 0
- Citations by year
- 2026: 12 · 2025: 16 · 2024: 17 · 2023: 17 · 2022: 17 · 2021: 27 · 2020: 15 · 2019: 38 · 2018: 16 · 2017: 22 · 2016: 13 · 2015: 30 · 2014: 42 · 2013: 30 · 2012: 21
- FWCI
- 7.09
- Type
- book
- Language
- en
- Open access
- closed
- Locations
- Oxford University Press eBooks (publishedVersion)
- Topics
- Physical Sciences › Physics and Astronomy › Astronomy and Astrophysics › Origins and Evolution of Life
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy of Biology and Scientific Explanation
- Physical Sciences › Computer Science › Computational Theory and Mathematics › Cellular Automata and Applications
- Keywords
- origin of life, chemoton, self-replication, biogenesis, philosophy of biology
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- The paper
- Ganti, T. (2003). The Principles of Life. Oxford University Press eBooks. https://doi.org/10.1093/acprof%3Aoso/9780198507260.001.0001