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Magnitude of the host nutritional responses to infection
Open accessAbstract
This review describes the scope, complexity, and magnitude of host nutritional responses throughout the course of an infectious process. These responses include prominent changes in nitrogen and protein metabolism, altered rates of carbohydrate and lipid production and utilization, and changes in mineral, electrolyte, trace element, and vitamin metabolism. It is postulated that these responses develop in a relatively predictable sequence which is influenced by the adequacy of host antimicrobial defense mechanisms, the severity and duration of illness, and specific localization of an infectious process within the body. In addition to hormonal regulatory effects, the metabolic and nutritional responses of the host are also influenced by biologically active substances released when host cells participate in phagocytic activity and local inflammatory responses.
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Cites
Cartwright, G. E., Lauritsen, M. A., Jones, P. J., Merrill, I. M., & Wintrobe, M. M. (1946) · Journal of Clinical Investigation · doi:10.1172/jci101690 · Cited by 150
Cited by
Trade‐offs in evolutionary immunology: just what is the cost of immunity?
Lochmiller, R. L., & Deerenberg, C. (2000) · Oikos · doi:10.1034/j.1600-0706.2000.880110.x · Cited by 2,110
Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones
Besedovsky, H., del Rey, A., Sorkin, E., & Dinarello, C. A. (1986) · Science · doi:10.1126/science.3014662 · Cited by 1,519
Horsburgh, M. J., Clements, M. O., Crossley, H., Ingham, E., & Foster, S. J. (2001) · Infection and Immunity · doi:10.1128/iai.69.6.3744-3754.2001 · Cited by 365
Horsburgh, M. J., Ingham, E., & Foster, S. J. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.2.468-475.2001 · Cited by 316
Muehlenbein, M. P., Hirschtick, J. L., Bonner, J. Z., & Swartz, A. M. (2010) · American Journal of Human Biology · doi:10.1002/ajhb.21045 · Cited by 178
Metadata
- Authors
- Beisel, W.
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1977-08
- Volume
- 30
- Issue
- 8
- Pages
- 1236-1247
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W1911402207
- Cited by
- 259
- References
- 1
- FWCI
- 5.01
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Beisel, W. (1977). Magnitude of the host nutritional responses to infection. The American Journal of Clinical Nutrition. https://doi.org/10.1093/ajcn/30.8.1236
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.