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Cited by 2,096

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Estimating the Relative Risk in Cohort Studies and Clinical Trials of Common Outcomes

McNutt, L.-A.·2003·American Journal of Epidemiology

Abstract

Logistic regression yields an adjusted odds ratio that approximates the adjusted relative risk when disease incidence is rare (<10%), while adjusting for potential confounders. For more common outcomes, the odds ratio always overstates the relative risk, sometimes dramatically. The purpose of this paper is to discuss the incorrect application of a proposed method to estimate an adjusted relative risk from an adjusted odds ratio, which has quickly gained popularity in medical and public health research, and to describe alternative statistical methods for estimating an adjusted relative risk when the outcome is common. Hypothetical data are used to illustrate statistical methods with readily accessible computer software.

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Metadata

Authors
McNutt, L.-A.
Venue
American Journal of Epidemiology
Published
2003-05-15
Volume
157
Issue
10
Pages
940-943
ISSN
0002-9262 (ISSN-L)
OpenAlex
W2153941399
Cited by
2,096
References
13
FWCI
25.75
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Estimating the Relative Risk in Cohort Studies and Clinical Trials of Common Outcomes. https://app.cochat.ai/papers/10.1093/aje/kwg074
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McNutt, L.-A. (2003). Estimating the Relative Risk in Cohort Studies and Clinical Trials of Common Outcomes. American Journal of Epidemiology. https://doi.org/10.1093/aje/kwg074

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.