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Cited by 331

The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

Explaining the Decline in Coronary Heart Disease Mortality in Finland between 1982 and 1997

Laatikainen, Tiina, Critchley, Julia, Vartiainen, Erkki, Salomaa, Veikko, Ketonen, Matti, Capewell, Simon·2005·American Journal of Epidemiology

Abstract

In Finland since the 1980s, coronary heart disease mortality has declined more than might be predicted by risk factor reductions alone. The aim of this study was to assess how much of the decline could be attributed to improved treatments and risk factor reductions. The authors used the cell-based IMPACT mortality model to synthesize effectiveness of treatments and risk factor reductions with data on treatments administered to patients and trends in cardiovascular risk factors in the population. Cardiovascular risk factors were measured in random samples of patients in 1982 (n=8,501) and 1997 (n=4,500). Mortality and treatment data were obtained from the National Causes of Death Register, Hospital Discharge Register, social insurance data, and medical records. Estimated and observed changes in coronary heart disease mortality were used as main outcome measures. Between 1982 and 1997, coronary heart disease mortality rates declined by 63%, with 373 fewer deaths in 1997 than expected from baseline mortality rates in 1982. Improved treatments explained approximately 23% of the mortality reduction, and risk factors explained some 53-72% of the reduction. These findings highlight the value of a comprehensive strategy that promotes primary prevention programs and actively supports secondary prevention. It also emphasizes the importance of maximizing population coverage of effective treatments.

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Metadata

Authors
Laatikainen, T., Critchley, J., Vartiainen, E., Salomaa, V., Ketonen, M., & Capewell, S.
Venue
American Journal of Epidemiology
Published
2005-09-08
Volume
162
Issue
8
Pages
764-773
ISSN
  • 0002-9262 (ISSN-L)
  • 1476-6256
OpenAlex
W2169631376
Cited by
331
References
48
FWCI
12.87
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Explaining the Decline in Coronary Heart Disease Mortality in Finland between 1982 and 1997. https://app.cochat.ai/papers/10.1093/aje/kwi274
The paper
Laatikainen, T., Critchley, J., Vartiainen, E., Salomaa, V., Ketonen, M., & Capewell, S. (2005). Explaining the Decline in Coronary Heart Disease Mortality in Finland between 1982 and 1997. American Journal of Epidemiology. https://doi.org/10.1093/aje/kwi274

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.