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Cited by 264

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Agreement Between 35 Published Frailty Scores in the General Population

Open access
Aguayo, Gloria A., Donneau, Anne-Françoise, Vaillant, Michel T., Schritz, Anna, Franco, Oscar H., Stranges, Saverio, Malisoux, Laurent, Guillaume, Michèle, Witte, Daniel R.·2017·American Journal of Epidemiology

Abstract

In elderly populations, frailty is associated with higher mortality risk. Although many frailty scores (FS) have been proposed, no single score is considered the gold standard. We aimed to evaluate the agreement between a wide range of FS in the English Longitudinal Study of Ageing (ELSA). Through a literature search, we identified 35 FS that could be calculated in ELSA wave 2 (2004-2005). We examined agreement between each frailty score and the mean of 35 FS, using a modified Bland-Altman model and Cohen's kappa (κ). Missing data were imputed. Data from 5,377 participants (ages ≥60 years) were analyzed (44.7% men, 55.3% women). FS showed widely differing degrees of agreement with the mean of all scores and between each pair of scores. Frailty classification also showed a very wide range of agreement (Cohen's κ = 0.10-0.83). Agreement was highest among "accumulation of deficits"-type FS, while accuracy was highest for multidimensional FS. There is marked heterogeneity in the degree to which various FS estimate frailty and in the identification of particular individuals as frail. Different FS are based on different concepts of frailty, and most pairs cannot be assumed to be interchangeable. Research results based on different FS cannot be compared or pooled.

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Metadata

Authors
Aguayo, G. A., Donneau, A.-F., Vaillant, M. T., Schritz, A., Franco, O. H., Stranges, S., Malisoux, L., Guillaume, M., & Witte, D. R.
Venue
American Journal of Epidemiology
Published
2017-06-15
Volume
186
Issue
4
Pages
420-434
ISSN
  • 0002-9262 (ISSN-L)
  • 1476-6256
OpenAlex
W2625596992
Cited by
264
References
57
FWCI
12.76
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Agreement Between 35 Published Frailty Scores in the General Population. https://app.cochat.ai/papers/10.1093/aje/kwx061
The paper
Aguayo, G. A., Donneau, A.-F., Vaillant, M. T., Schritz, A., Franco, O. H., Stranges, S., Malisoux, L., Guillaume, M., & Witte, D. R. (2017). Agreement Between 35 Published Frailty Scores in the General Population. American Journal of Epidemiology. https://doi.org/10.1093/aje/kwx061

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