Cardiometabolic Health Disparities in Native Hawaiians and Other Pacific Islanders
Open accessAbstract
Elimination of health disparities in the United States is a national health priority. Cardiovascular disease, diabetes, and obesity are key features of what is now referred to as the "cardiometabolic syndrome," which disproportionately affects racial/ethnic minority populations, including Native Hawaiians and other Pacific Islanders (NHOPI). Few studies have adequately characterized the cardiometabolic syndrome in high-risk populations such as NHOPI. The authors systematically assessed the existing literature on cardiometabolic disorders among NHOPI to understand the best approaches to eliminating cardiometabolic health disparities in this population. Articles were identified from database searches performed in PubMed and MEDLINE from January 1998 to December 2008; 43 studies were included in the review. There is growing confirmatory evidence that NHOPI are one of the highest-risk populations for cardiometabolic diseases in the United States. Most studies found increased prevalences of diabetes, obesity, and cardiovascular risk factors among NHOPI. The few experimental intervention studies found positive results. Methodological issues included small sample sizes, sample bias, inappropriate racial/ethnic aggregation of NHOPI with Asians, and a limited number of intervention studies. Significant gaps remain in the understanding of cardiometabolic health disparities among NHOPI in the United States. More experimental intervention studies are needed to examine promising approaches to reversing the rising tide of cardiometabolic health disparities in NHOPI.
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Emerging research suggests that some Asian subgroups, and Pacific Islanders, may be at higher risk for CVD and poorer outcomes than NHW, and that there are important differences among API subgroups.
“Emerging research suggests that some Asian subgroups, and Pacific Islanders, may be at higher risk for CVD and poorer outcomes than NHW, and that there are important differences among API subgroups [4-8].”
From Prevalence of cardiovascular disease among Asian, Pacific Islander and multi-race populations in Hawai’i and California (2023) · cites this paper as [5]
The Results (Cardiovascular disease; page not supplied) report more hypertension and high cholesterol among NHOPI women than among whites, as well as differences in cardiac treatment. The Introduction reports higher cardiovascular mortality among Native Hawaiians than among Japanese, supporting differences between subgroups. This paper does not establish that Asian subgroups have higher CVD risk or poorer outcomes than non-Hispanic whites, nor does it directly compare Pacific Islanders’ CVD outcomes with that group. (LLM, conf=0.84)
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- Authors
- Mau, M. K., Sinclair, K., Saito, E. P., Baumhofer, K. N., & Kaholokula, J. K.
- Affiliations
- University of Hawaiʻi at Mānoa (US)
- Venue
- Epidemiologic Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-06-16
- Volume
- 31
- Issue
- 1
- Pages
- 113-129
- ISSN
- 0193-936X (ISSN-L)
- 1478-6729
- PMC
- PMC2893232
- OpenAlex
- W2167361004
- Cited by
- 253
- References
- 3
- Citations by year
- 2026: 10 · 2025: 15 · 2024: 13 · 2023: 24 · 2022: 26 · 2021: 24 · 2020: 15 · 2019: 20 · 2018: 11 · 2017: 11 · 2016: 15 · 2015: 11 · 2014: 16 · 2013: 14 · 2012: 11
- FWCI
- 1.62
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Epidemiologic Reviews (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- University Libraries (University of Maryland) (submittedVersion)
- HighWire Press Open Archive (submittedVersion)
- Digital Repository at the University of Maryland (University of Maryland College Park)
- Funders
- National Institutes of Health (5r24md001660-11)
- National Heart, Lung, and Blood Institute (U01HL079163)
- National Institute on Minority Health and Health Disparities (S21MD000228, P20MD000173, R24 MD-001660)
- Topics
- Health Sciences › Health Professions › General Health Professions › Indigenous Health and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Keywords
- Native Hawaiians and other Pacific Islanders, cardiometabolic syndrome, diabetes prevalence, obesity prevalence, cardiovascular risk factors, minority health, health interventions
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Cardiovascular Diseases, Diabetes Mellitus, Type 2, Hawaii, Humans, Middle Aged, Obesity, Pacific Islands, Metabolic Syndrome, Minority Health, Health Status Disparities, Healthcare Disparities, Young Adult
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