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The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Comparative genome assembly

Open access
Pop, M.·2004·Briefings in Bioinformatics

Abstract

One of the most complex and computationally intensive tasks of genome sequence analysis is genome assembly. Even today, few centres have the resources, in both software and hardware, to assemble a genome from the thousands or millions of individual sequences generated in a whole-genome shotgun sequencing project. With the rapid growth in the number of sequenced genomes has come an increase in the number of organisms for which two or more closely related species have been sequenced. This has created the possibility of building a comparative genome assembly algorithm, which can assemble a newly sequenced genome by mapping it onto a reference genome. We describe here a novel algorithm for comparative genome assembly that can accurately assemble a typical bacterial genome in less than four minutes on a standard desktop computer. The software is available as part of the open-source AMOS project.

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Metadata

Authors
Pop, M.
Venue
Briefings in Bioinformatics
Published
2004-01-01
Volume
5
Issue
3
Pages
237-248
ISSN
  • 1467-5463 (ISSN-L)
  • 1477-4054
OpenAlex
W1841715584
Cited by
232
References
5
FWCI
2.41
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Comparative genome assembly. https://app.cochat.ai/papers/10.1093/bib/5.3.237
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Pop, M. (2004). Comparative genome assembly. Briefings in Bioinformatics. https://doi.org/10.1093/bib/5.3.237

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