A broken promise: microbiome differential abundance methods do not control the false discovery rate
Hawinkel, Stijn, Mattiello, Federico, Bijnens, Luc, Thas, Olivier·2019·Briefings in Bioinformatics
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- Inferring absolute counts from proportions by constraining multivariate normal distributionsJeffrey R. Hage, Devin C. Koestler, Brock C. Christensen · 2026 · npj Systems Biology and Applications
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- Additional file 2 of A comprehensive evaluation of microbial differential abundance analysis methods: current status and potential solutionsYang, Lu, Chen, Jun · 2022 · Figshare
- Additional file 8 of mbImpute: an accurate and robust imputation method for microbiome dataRuochen Jiang, Li, Wei Vivian, Jingyi Jessica Li · 2021 · Figshare
- Additional file 3 of A realistic benchmark for differential abundance testing and confounder adjustment in human microbiome studiesJakob Wirbel, Morgan Essex, Forslund, Sofia Kirke, Zeller, Georg · 2024 · Figshare
- Additional file 4 of A realistic benchmark for differential abundance testing and confounder adjustment in human microbiome studiesJakob Wirbel, Morgan Essex, Forslund, Sofia Kirke, Zeller, Georg · 2024 · Figshare
- Additional file 2 of A realistic benchmark for differential abundance testing and confounder adjustment in human microbiome studiesJakob Wirbel, Morgan Essex, Forslund, Sofia Kirke, Zeller, Georg · 2024 · Figshare
- Additional file 1 of Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolboxJakob Wirbel, Konrad Zych, Morgan Essex, Nicolai Karcher, Ece Kartal, Guillem Salazar, Peer Bork, Shinichi Sunagawa, Zeller, Georg · 2021 · Figshare
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- Additional file 1 of mbImpute: an accurate and robust imputation method for microbiome dataRuochen Jiang, Li, Wei Vivian, Li, Jingyi Jessica · 2021 · Figshare
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- Additional file 1 of Relative abundance data can misrepresent heritability of the microbiomeMarjolein Bruijning, Julien F. Ayroles, Lucas P. Henry, Britt Louise Koskella, Kyle Meyer, Charlotte Jessica E. Metcalf · 2023 · Figshare
- Additional file 3 of LinDA: linear models for differential abundance analysis of microbiome compositional dataZhou, Huijuan, Kejun He, Chen, Jun, Zhang, Xianyang · 2022 · Figshare
- Additional file 1 of A realistic benchmark for differential abundance testing and confounder adjustment in human microbiome studiesJakob Wirbel, Morgan Essex, Forslund, Sofia Kirke, Zeller, Georg · 2024 · Figshare
- Additional file 10 of Comparison study of differential abundance testing methods using two large Parkinson disease gut microbiome datasets derived from 16S amplicon sequencingWallen, Zachary D. · 2021 · Figshare
- Additional file 1 of Randomized quantile residuals for diagnosing zero-inflated generalized linear mixed models with applications to microbiome count dataWei Guo Bai, Dong, Mei, Longhai Li, Cindy Xin Feng, Xu, Wei · 2021 · Figshare
- Additional file 2 of LinDA: linear models for differential abundance analysis of microbiome compositional dataZhou, Huijuan, Kejun He, Chen, Jun, Zhang, Xianyang · 2022 · Figshare
- Additional file 2 of Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolboxJakob Wirbel, Konrad Zych, Morgan Essex, Nicolai Karcher, Ece Kartal, Guillem Salazar, Peer Bork, Shinichi Sunagawa, Zeller, Georg · 2021 · Figshare
- Additional file 1 of Clipper: p-value-free FDR control on high-throughput data from two conditionsXinzhou Ge, Chen, Yiling Elaine, Song, Dongyuan, MeiLu McDermott, Kyla Woyshner, Antigoni Manousopoulou, Ning Wang, Li, Wei, Wang, Leo D., Jingyi Jessica Li · 2021 · Figshare
- Additional file 1 of ProgPerm: Progressive permutation for a dynamic representation of the robustness of microbiome discoveriesZhang, Liangliang, Yushu Shi, Do, Kim-Anh, Christine B. Peterson, Jenq, Robert R. · 2021 · Figshare
- Additional file 11 of Comparison study of differential abundance testing methods using two large Parkinson disease gut microbiome datasets derived from 16S amplicon sequencingWallen, Zachary D. · 2021 · Figshare
- Additional file 1 of Accommodating multiple potential normalizations in microbiome associations studiesHoseung Song, Ling, Wodan, Zhao, Ni, Anna Plantinga, Courtney Ann Broedlow, Nichole R. Klatt, Tiffany Hensley‐McBain, Wu, Michael C. · 2023 · Figshare
- Additional file 1 of Powerful and robust non-parametric association testing for microbiome data via a zero-inflated quantile approach (ZINQ)Ling, Wodan, Zhao, Ni, Anna Plantinga, Lenore J. Launer, Anthony A. Fodor, Meyer, Katie A., Wu, Michael C. · 2021 · Figshare
- Additional file 1 of PhyloMed: a phylogeny-based test of mediation effect in microbiomeQilin Hong, Chen, Guanhua, Tang, Zheng-Zheng · 2023 · Figshare
- Additional file 3 of Clipper: p-value-free FDR control on high-throughput data from two conditionsXinzhou Ge, Chen, Yiling Elaine, Song, Dongyuan, MeiLu McDermott, Kyla Woyshner, Antigoni Manousopoulou, Ning Wang, Li, Wei, Wang, Leo D., Jingyi Jessica Li · 2021 · Figshare
- Additional file 3 of Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolboxJakob Wirbel, Konrad Zych, Morgan Essex, Nicolai Karcher, Ece Kartal, Guillem Salazar, Peer Bork, Shinichi Sunagawa, Zeller, Georg · 2021 · Figshare
- Additional file 2 of PhyloMed: a phylogeny-based test of mediation effect in microbiomeQilin Hong, Chen, Guanhua, Tang, Zheng-Zheng · 2023 · Figshare
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