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BioMercator: integrating genetic maps and QTL towards discovery of candidate genes

Open access
Arcade, Anne, Labourdette, Aymeric, Falque, Matthieu, Mangin, Brigitte, Chardon, Fabien, Charcosset, Alain, Joets, Johann·2004·Bioinformatics

Abstract

Summary: Breeding programs face the challenge of integrating information from genomics and from quantitative trait loci (QTL) analysis in order to identify genomic sequences controlling the variation of important traits. Despite the development of integrative databases, building a consensus map of genes, QTL and other loci gathered from multiple maps remains a manual and tedious task. Nevertheless, this is a critical step to reveal co-locations between genes and QTL. Another important matter is to determine whether QTL linked to same traits or related ones is detected in independent experiments and located in the same region, and represents a single locus or not. Statistical tools such as meta-analysis can be used to answer this question. BioMercator has been developed to automate map compilation and QTL meta-analysis, and to visualize co-locations between genes and QTL through a graphical interface. Availability: Available upon request (http://moulon/~bioinfo/BioMercator/). Free of charge for academic use.

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Crossref · 10.1093/bioinformatics/bth230

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Metadata

Authors
Arcade, A., Labourdette, A., Falque, M., Mangin, B., Chardon, F., Charcosset, A., & Joets, J.
Venue
Bioinformatics
Published
2004-04-01
Volume
20
Issue
14
Pages
2324-2326
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2142178963
Cited by
490
References
1
FWCI
4.21
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: BioMercator: integrating genetic maps and QTL towards discovery of candidate genes. https://app.cochat.ai/papers/10.1093/bioinformatics/bth230
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Arcade, A., Labourdette, A., Falque, M., Mangin, B., Chardon, F., Charcosset, A., & Joets, J. (2004). BioMercator: integrating genetic maps and QTL towards discovery of candidate genes. Bioinformatics. https://doi.org/10.1093/bioinformatics/bth230

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