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Cited by 290

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

GlycoBase and autoGU: tools for HPLC-based glycan analysis

Open access
Campbell, Matthew P., Royle, Louise, Radcliffe, Catherine M., Dwek, Raymond A., Rudd, Pauline M.·2008·Bioinformatics

Abstract

Summary: The development of robust high-performance liquid chromatography (HPLC) technologies continues to improve the detailed analysis and sequencing of glycan structures released from glycoproteins. Here, we present a database (GlycoBase) and analytical tool (autoGU) to assist the interpretation and assignment of HPLC-glycan profiles. GlycoBase is a relational database which contains the HPLC elution positions for over 350 2-AB labelled N-glycan structures together with predicted products of exoglycosidase digestions. AutoGU assigns provisional structures to each integrated HPLC peak and, when used in combination with exoglycosidase digestions, progressively assigns each structure automatically based on the footprint data. These tools are potentially very promising and facilitate basic research as well as the quantitative high-throughput analysis of low concentrations of glycans released from glycoproteins. Availability: http://glycobase.ucd.ie Contact: matthew.campbell@nibrt.ie

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Metadata

Authors
Campbell, M. P., Royle, L., Radcliffe, C. M., Dwek, R. A., & Rudd, P. M.
Venue
Bioinformatics
Published
2008-03-14
Volume
24
Issue
9
Pages
1214-1216
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W18344517
Cited by
290
References
11
FWCI
7.32
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: GlycoBase and autoGU: tools for HPLC-based glycan analysis. https://app.cochat.ai/papers/10.1093/bioinformatics/btn090
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Campbell, M. P., Royle, L., Radcliffe, C. M., Dwek, R. A., & Rudd, P. M. (2008). GlycoBase and autoGU: tools for HPLC-based glycan analysis. Bioinformatics. https://doi.org/10.1093/bioinformatics/btn090

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