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ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

Yu, Guangchuang, Wang, Li-Gen, He, Qing-Yu·2015·Bioinformatics

Abstract

Summary: ChIPseeker is an R package for annotating ChIP-seq data analysis. It supports annotating ChIP peaks and provides functions to visualize ChIP peaks coverage over chromosomes and profiles of peaks binding to TSS regions. Comparison of ChIP peak profiles and annotation are also supported. Moreover, it supports evaluating significant overlap among ChIP-seq datasets. Currently, ChIPseeker contains 15 000 bed file information from GEO database. These datasets can be downloaded and compare with user’s own data to explore significant overlap datasets for inferring co-regulation or transcription factor complex for further investigation. Availability and implementation: ChIPseeker is released under Artistic-2.0 License. The source code and documents are freely available through Bioconductor (http://www.bioconductor.org/packages/release/bioc/html/ChIPseeker.html). Contact: guangchuangyu@gmail.com or tqyhe@jnu.edu.cn Supplementary information: Supplementary data are available at Bioinformatics online.

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Research works printed but not linked: 8

  1. Gentleman, 2004, Bioconductor: open software development for computational biology and bioinformatics, Genome Biol., 5, R80, 10.1186/gb-2004-5-10-r80 · DOI · Paper page
  2. Huang, 2013, PAVIS: a tool for peak annotation and visualization, Bioinformatics, 29, 3097, 10.1093/bioinformatics/btt520 · DOI
  3. Lawrence, 2013, Software for computing and annotating genomic ranges, PLoS Comput. Biol., 9, e1003118, 10.1371/journal.pcbi.1003118 · DOI · Paper page
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Metadata

Authors
Yu, G., Wang, L.-G., & He, Q.-Y.
Venue
Bioinformatics
Published
2015-03-11
Volume
31
Issue
14
Pages
2382-2383
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2170830174
Cited by
4,362
References
1
FWCI
21.74
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization. https://app.cochat.ai/papers/10.1093/bioinformatics/btv145
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Yu, G., Wang, L.-G., & He, Q.-Y. (2015). ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization. Bioinformatics. https://doi.org/10.1093/bioinformatics/btv145

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