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Pavian: interactive analysis of metagenomics data for microbiome studies and pathogen identification

Open access
Breitwieser, Florian P, Salzberg, Steven L·2020·Bioinformatics

Abstract

Summary: Pavian is a web application for exploring classification results from metagenomics experiments. With Pavian, researchers can analyze, visualize and transform results from various classifiers—such as Kraken, Centrifuge and MethaPhlAn—using interactive data tables, heatmaps and Sankey flow diagrams. An interactive alignment coverage viewer can help in the validation of matches to a particular genome, which can be crucial when using metagenomics experiments for pathogen detection. Availability and implementation: Pavian is implemented in the R language as a modular Shiny web app and is freely available under GPL-3 from http://github.com/fbreitwieser/pavian.

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Research works printed but not linked: 6

  1. Bostock, 2011, D³ data-driven documents, IEEE Trans. Vis. Comput. Graph, 17, 2301, 10.1109/TVCG.2011.185 · DOI · Paper page
  2. Breitwieser, 2018, KrakenUniq: confident and fast metagenomics classification using unique k-mer counts, Genome Biol, 19, 198, 10.1186/s13059-018-1568-0 · DOI · Paper page
  3. Breitwieser, 2017, A review of methods and databases for metagenomic classification and assembly, Brief. Bioinform
  4. McMurdie, 2015, Shiny-phyloseq: web application for interactive microbiome analysis with provenance tracking, Bioinformatics, 31, 282, 10.1093/bioinformatics/btu616 · DOI · Paper page
  5. Salzberg, 2016, Next-generation sequencing in neuropathologic diagnosis of infections of the nervous system, Neurol. Neuroimmunol. Neuroinflamm, 3, e251, 10.1212/NXI.0000000000000251 · doi:10.1212/nxi.0000000000000251
  6. Wagner, 2018, Metaviz: interactive statistical and visual analysis of metagenomic data, Nucleic Acids Res, 46, 2777, 10.1093/nar/gky136 · DOI

Cited by

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Metadata

Authors
Breitwieser, F. P., & Salzberg, S. L.
Venue
Bioinformatics
Published
2019-09-25
Volume
36
Issue
4
Pages
1303-1304
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2977180444
Cited by
483
References
5
FWCI
10.38
Type
journal article
Language
en
Open access
bronze
Funders
  • National Institutes of Health (R35-GM130151, R01-HG006677)
  • U. S. Army Research Office (W911NF-14-1-0490)

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CoChat. (2026). Citation check: Pavian: interactive analysis of metagenomics data for microbiome studies and pathogen identification. https://app.cochat.ai/papers/10.1093/bioinformatics/btz715
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Breitwieser, F. P., & Salzberg, S. L. (2020). Pavian: interactive analysis of metagenomics data for microbiome studies and pathogen identification. Bioinformatics. https://doi.org/10.1093/bioinformatics/btz715

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