The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Joint frailty models for recurring events and death using maximum penalized likelihood estimation: application on cancer events
Open accessAbstract
The observation of repeated events for subjects in cohort studies could be terminated by loss to follow-up, end of study, or a major failure event such as death. In this context, the major failure event could be correlated with recurrent events, and the usual assumption of noninformative censoring of the recurrent event process by death, required by most statistical analyses, can be violated. Recently, joint modeling for 2 survival processes has received considerable attention because it makes it possible to study the joint evolution over time of 2 processes and gives unbiased and efficient parameters. The most commonly used estimation procedure in the joint models for survival events is the expectation maximization algorithm. We show how maximum penalized likelihood estimation can be applied to nonparametric estimation of the continuous hazard functions in a general joint frailty model with right censoring and delayed entry. The simulation study demonstrates that this semiparametric approach yields satisfactory results in this complex setting. As an illustration, such an approach is applied to a prospective cohort with recurrent events of follicular lymphomas, jointly modeled with death.
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“In addition, to account for informative censoring due to cardiovascular death, we calculated the hazard ratio for total nonfatal events using a joint frailty model (52).”
From Effects of Icosapent Ethyl on Total Ischemic Events (2019) · cites this paper as [52]
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Cites
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The Statistical Analysis of Failure Time Data
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Follicular lymphoma international prognostic index
Solal-Céligny, P. (2006) · Current Treatment Options in Oncology · doi:10.1007/s11864-006-0036-3 · Cited by 1,339
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Transcatheter Mitral-Valve Repair in Patients with Heart Failure
Stone, G. W., Lindenfeld, J., Abraham, W. T., Kar, S., Lim, D. S., Mishell, J. M., Whisenant, B., Grayburn, P. A., Rinaldi, M., Kapadia, S. R., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1806640 · Cited by 3,017
Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation
Stone, G. W., Abraham, W. T., Lindenfeld, J. M., Kar, S., Grayburn, P. A., Lim, D. S., Mishell, J. M., Whisenant, B. K., Rinaldi, M., Kapadia, S. R., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2300213 · Cited by 376
Zsebo, K., Yaroshinsky, A., Rudy, J. J., Wagner, K., Greenberg, B., Jessup, M., & Hajjar, R. J. (2014) · Circulation Research · doi:10.1161/circresaha.113.302421 · Cited by 315
Heart Failure With Recovered Ejection Fraction
Basuray, A., French, B. C., Ky, B., Vorovich, E., Olt, C. K., Sweitzer, N. K., Cappola, T. P., & Fang, J. C.-T. (2014) · Circulation · doi:10.1161/circulationaha.113.006855 · Cited by 315
Effects of Icosapent Ethyl on Total Ischemic Events
Bhatt, D. L., Steg, P. G., Miller, M., Brinton, E. A., Jacobson, T. A., Ketchum, S. B., Doyle, R. T., Juliano, R. A., Jiao, L., Granowitz, C., et al. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2019.02.032 · Cited by 259
Metadata
- Authors
- Rondeau, V., Mathoulin-Pelissier, S., Jacqmin-Gadda, H., Brouste, V., & Soubeyran, P.
- Affiliations
- Inserm (FR)
- Institut Bergonié (FR)
- Corresponding author
- Rondeau, V.
- Venue
- Biostatistics
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-12-06
- Volume
- 8
- Issue
- 4
- Pages
- 708-721
- ISSN
- 1465-4644 (ISSN-L)
- 1468-4357
- OpenAlex
- W2121046269
- Cited by
- 211
- References
- 29
- Citations by year
- 2026: 11 · 2025: 13 · 2024: 9 · 2023: 9 · 2022: 12 · 2021: 20 · 2020: 18 · 2019: 28 · 2018: 16 · 2017: 10 · 2016: 10 · 2015: 5 · 2014: 14 · 2013: 7 · 2012: 9
- FWCI
- 2.20
- Type
- journal article
- Language
- en
- Open access
- green
- shs.hal.science
- Licence
- other-oa
- Locations
- Biostatistics (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- HAL (submittedVersion)
- Topics
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Distribution Estimation and Applications
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Inference
- Keywords
- joint frailty model, recurrent events, death, right censoring, delayed entry, follicular lymphoma, loss to follow-up
- MeSH terms
- Biometry, Humans, Lymphoma, Follicular, Models, Biological, Neoplasms, Recurrence, Models, Statistical, Likelihood Functions
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