The DOI matches its Crossref record.
PROGRESSIVE CENTRIPETAL DEGENERATION OF AXONS IN SMALL FIBRE DIABETIC POLYNEUROPATHY: A CLINICAL AND PATHOLOGICAL STUDY
Abstract
A clinicopathological study is presented of 5 patients with a pseudosyringomyelic dissociation of sensory loss and severe autonomic disturbances related to diabetic polyneuropathy. Sensory loss which followed a pattern that suggested a length-related degeneration of fibres was associated with spontaneous pains in 3 patients. Plantar ulcers and neurogenic arthropathies were also present in 3 patients. The pathological changes in sural nerve biopsies included a severe loss of unmyelinated and small myelinated axons which appeared to be involved earlier than larger myelinated fibres. Distal degeneration of single fibres with subsequent axonal sprouting from the proximal axon was demonstrated in all patients. This severe axonal neuropathy was associated with primary and secondary segmental demyelination. Our observations are consistent with a progressive centripetal degeneration of axons in predominantly sensory diabetic polyneuropathy.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy
Sloan, G., Selvarajah, D., & Tesfaye, S. (2021) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00496-z · Cited by 534
The natural history of acute painful neuropathy in diabetes mellitus.
Archer, A. G., Watkins, P. J., Thomas, P. K., Sharma, A. K., & Payan, J. (1983) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.46.6.491 · Cited by 342
Treatment-induced diabetic neuropathy: A reversible painful autonomic neuropathy
Gibbons, C. H., & Freeman, R. (2010) · Annals of Neurology · doi:10.1002/ana.21952 · Cited by 213
Acute painful diabetic neuropathy precipitated by strict glycaemic control
Llewelyn, J. G., Thomas, P. K., Fonseca, V., King, R. H. M., & Dandona, P. (1986) · Acta Neuropathologica · doi:10.1007/bf00685978 · Cited by 121
Prospective evaluation of somatic and autonomic small fibers in selected autonomic neuropathies
Singer, W., Spies, J. M., McArthur, J., Low, J., Griffin, J. W., Nickander, K. K., Gordon, V., & Low, P. A. (2004) · Neurology · doi:10.1212/01.wnl.0000110313.39239.82 · Cited by 105
Metadata
- Authors
- SAID, G., SLAMA, G., & SELVA, J.
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 1983
- Volume
- 106
- Issue
- 4
- Pages
- 791-807
- ISSN
- 0006-8950 (ISSN-L)
- 1460-2156
- OpenAlex
- W1969618497
- Cited by
- 251
- References
- 0
- FWCI
- 7.02
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: PROGRESSIVE CENTRIPETAL DEGENERATION OF AXONS IN SMALL FIBRE DIABETIC POLYNEUROPATHY: A CLINICAL AND PATHOLOGICAL STUDY. https://app.cochat.ai/papers/10.1093/brain/106.4.791
- The paper
- SAID, G., SLAMA, G., & SELVA, J. (1983). PROGRESSIVE CENTRIPETAL DEGENERATION OF AXONS IN SMALL FIBRE DIABETIC POLYNEUROPATHY: A CLINICAL AND PATHOLOGICAL STUDY. Brain. https://doi.org/10.1093/brain/106.4.791
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
