Cited by 69Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsNeurology and Historical Studies

Alzheimer’s disease in the 100 years since Alzheimer’s death

Ryan, Natalie S., Rossor, Martin N., Fox, Nick C.·2015·Brain

Abstract

The last 100 years have seen major changes in concepts of the nature of Alzheimer’s disease, its prevalence and whom it affects. Ryan et al. discuss some of the factors that have contributed to this evolution, leading to contemporary views of this disorder.

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Crossref · 10.1093/brain/awv316

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1 of 1 references verified0 citation errors · 0 not checkable

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  • The presence of extracellular amyloid plaques and intracellular neurofibrillary tangles is required for diagnosis of Alzheimer's disease.

    “As first observed over 100 years ago [25], the presence of extracellular amyloid plaques and intracellular neurofibrillary tangles is required for diagnosis.”

    From The neuropathological diagnosis of Alzheimer's disease (2019) · cites this paper as [25]

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Authors
Ryan, N. S., Rossor, M. N., & Fox, N. C.
Affiliations
UCL Queen Square Institute of Neurology (GB)
Venue
Brain
Published
2015-11-04
Volume
138
Issue
12
Pages
3816-3821
ISSN
  • 0006-8950 (ISSN-L)
  • 1460-2156
OpenAlex
W2104977898
Cited by
69
References
1
Citations by year
2026: 4 · 2025: 8 · 2024: 6 · 2023: 5 · 2022: 9 · 2021: 8 · 2020: 10 · 2019: 6 · 2018: 7 · 2017: 2 · 2016: 3 · 2015: 1
FWCI
3.52
Type
journal article
Language
en
Open access
closed
Locations
  • Brain (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • HighWire Press Open Archive (submittedVersion)
Funders
National Institute for Health and Care Research (NF-SI-0512-10033, NF-SI-0513-10134, NF-SI-0508-10123)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Life Sciences › Neuroscience › Neurology › Neurology and Historical Studies
Keywords
Alzheimer's disease, history of Alzheimer's disease, illness beliefs, prevalence, affected populations, history of neurology
MeSH terms
Alzheimer Disease, Humans, History, 20th Century, History, 21st Century

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