The DOI matches its Crossref record.
Urinary bladder carcinogenicity of dimethylarsinic acid in male F344 rats
Open accessAbstract
The present study was conducted to determine the carcinogenicity of dimethylarsinic acid (DMA) administered to male F344 rats in a 2 year bioassay. A total of 144 rats (10 weeks old at the start) were divided into four groups of 36 rats each. Groups 1-4 received DMA (purity 100%) at concentrations of 200, 50, 12.5 and 0 p.p.m. in the drinking water, respectively, for 104 weeks. From weeks 97 to 104, urinary bladder tumors were observed in 12 of 31, eight of 31 and none of 33 in groups 1-3, respectively. No bladder tumors were observed in group 4. The present study demonstrated that long-term p. o. administration of DMA induced urinary bladder carcinomas in male F344 rats. Therefore, the results indicate that DMA is carcinogenic for the rat urinary bladder, which may be related to the human carcinogenicity of arsenicals.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Arsenic Exposure and Toxicology: A Historical Perspective
Hughes, M. F., Beck, B. D., Chen, Y., Lewis, A. S., & Thomas, D. J. (2011) · Toxicological Sciences · doi:10.1093/toxsci/kfr184 · Cited by 1,312
Mechanism of arsenic carcinogenesis: an integrated approach
Rossman, T. G. (2003) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/j.mrfmmm.2003.07.009 · Cited by 559
Methylated Arsenic Species in Rice: Geographical Variation, Origin, and Uptake Mechanisms
Zhao, F.-J., Zhu, Y.-G., & Meharg, A. A. (2013) · Environmental Science & Technology · doi:10.1021/es304295n · Cited by 353
Arsenic in the aetiology of cancer
Tapio, S., & Grosche, B. (2006) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2006.02.001 · Cited by 334
Metabolism of arsenic and its toxicological relevance
Watanabe, T., & Hirano, S. (2013) · Archives of Toxicology · doi:10.1007/s00204-012-0904-5 · Cited by 324
Metadata
- Authors
- Wei, M., Wanibuchi, H., Yamamoto, S., Li, W., & Fukushima, S.
- Venue
- Carcinogenesis
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-09
- Volume
- 20
- Issue
- 9
- Pages
- 1873-1876
- ISSN
- 0143-3334 (ISSN-L)
- 1460-2180
- OpenAlex
- W2038673475
- Cited by
- 190
- References
- 0
- FWCI
- 17.48
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Urinary bladder carcinogenicity of dimethylarsinic acid in male F344 rats. https://app.cochat.ai/papers/10.1093/carcin/20.9.1873
- The paper
- Wei, M., Wanibuchi, H., Yamamoto, S., Li, W., & Fukushima, S. (1999). Urinary bladder carcinogenicity of dimethylarsinic acid in male F344 rats. Carcinogenesis. https://doi.org/10.1093/carcin/20.9.1873
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
